Gut microbiota and intestinal FXR mediate the clinical benefits of metformin L Sun, C Xie, G Wang, Y Wu, Q Wu, X Wang, J Liu, Y Deng, J Xia, B Chen, ... Nature medicine 24 (12), 1919-1929, 2018 | 791 | 2018 |
Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease C Jiang, C Xie, F Li, L Zhang, RG Nichols, KW Krausz, J Cai, Y Qi, ... The Journal of clinical investigation 125 (1), 386-402, 2015 | 673 | 2015 |
Intermittent fasting promotes white adipose browning and decreases obesity by shaping the gut microbiota G Li, C Xie, S Lu, RG Nichols, Y Tian, L Li, D Patel, Y Ma, CN Brocker, ... Cell metabolism 26 (4), 672-685. e4, 2017 | 657 | 2017 |
Intestine farnesoid X receptor agonist and the gut microbiota activate G‐protein bile acid receptor‐1 signaling to improve metabolism P Pathak, C Xie, RG Nichols, JM Ferrell, S Boehme, KW Krausz, ... Hepatology 68 (4), 1574-1588, 2018 | 445 | 2018 |
Persistent organic pollutants modify gut microbiota–host metabolic homeostasis in mice through aryl hydrocarbon receptor activation L Zhang, RG Nichols, J Correll, IA Murray, N Tanaka, PB Smith, ... Environmental health perspectives 123 (7), 679-688, 2015 | 302 | 2015 |
The microbiome modulating activity of bile acids Y Tian, W Gui, I Koo, PB Smith, EL Allman, RG Nichols, B Rimal, J Cai, ... Gut microbes 11 (4), 979-996, 2020 | 150 | 2020 |
The relationship between the gut microbiome and host gene expression: a review RG Nichols, ER Davenport Human genetics 140 (5), 747-760, 2021 | 127 | 2021 |
Farnesoid X receptor signaling shapes the gut microbiota and controls hepatic lipid metabolism L Zhang, C Xie, RG Nichols, SHJ Chan, C Jiang, R Hao, PB Smith, J Cai, ... MSystems 1 (5), 10.1128/msystems. 00070-16, 2016 | 99 | 2016 |
Metabolomics reveals that aryl hydrocarbon receptor activation by environmental chemicals induces systemic metabolic dysfunction in mice L Zhang, E Hatzakis, RG Nichols, R Hao, J Correll, PB Smith, CR Chiaro, ... Environmental science & technology 49 (13), 8067-8077, 2015 | 94 | 2015 |
Berberine directly affects the gut microbiota to promote intestinal farnesoid X receptor activation Y Tian, J Cai, W Gui, RG Nichols, I Koo, J Zhang, M Anitha, AD Patterson Drug Metabolism and Disposition 47 (2), 86-93, 2019 | 88 | 2019 |
Dietary broccoli impacts microbial community structure and attenuates chemically induced colitis in mice in an Ah receptor dependent manner TD Hubbard, IA Murray, RG Nichols, K Cassel, M Podolsky, G Kuzu, ... Journal of functional foods 37, 685-698, 2017 | 81 | 2017 |
Interplay between the host, the human microbiome, and drug metabolism RG Nichols, JM Peters, AD Patterson Human genomics 13, 1-10, 2019 | 74 | 2019 |
Expression of the aryl hydrocarbon receptor contributes to the establishment of intestinal microbial community structure in mice IA Murray, RG Nichols, L Zhang, AD Patterson, GH Perdew Scientific Reports 6 (1), 33969, 2016 | 73 | 2016 |
Vitamin A deficiency in mice alters host and gut microbial metabolism leading to altered energy homeostasis Y Tian, RG Nichols, J Cai, AD Patterson, MT Cantorna The Journal of nutritional biochemistry 54, 28-34, 2018 | 64 | 2018 |
Modulation of colon cancer by nutmeg F Li, XW Yang, KW Krausz, RG Nichols, W Xu, AD Patterson, FJ Gonzalez Journal of proteome research 14 (4), 1937-1946, 2015 | 52 | 2015 |
Vitamin D regulates the microbiota to control the numbers of RORγt/FoxP3+ regulatory T cells in the colon MT Cantorna, YD Lin, J Arora, S Bora, Y Tian, RG Nichols, AD Patterson Frontiers in immunology 10, 1772, 2019 | 50 | 2019 |
Perfluorooctane sulfonate alters gut microbiota-host metabolic homeostasis in mice L Zhang, B Rimal, RG Nichols, Y Tian, PB Smith, E Hatzakis, SC Chang, ... Toxicology 431, 152365, 2020 | 49 | 2020 |
Prebiotic effects of white button mushroom (Agaricus bisporus) feeding on succinate and intestinal gluconeogenesis in C57BL/6 mice Y Tian, RG Nichols, P Roy, W Gui, PB Smith, J Zhang, Y Lin, V Weaver, ... Journal of Functional Foods 45, 223-232, 2018 | 38 | 2018 |
The aryl hydrocarbon receptor as a moderator of host-microbiota communication L Zhang, RG Nichols, AD Patterson Current Opinion in Toxicology 2, 30-35, 2017 | 34 | 2017 |
Metabolic impact of persistent organic pollutants on gut microbiota Y Tian, W Gui, B Rimal, I Koo, PB Smith, RG Nichols, J Cai, Q Liu, ... Gut Microbes 12 (1), 1848209, 2020 | 29 | 2020 |