Advancing schizophrenia drug discovery: optimizing rodent models to bridge the translational gap J Pratt, C Winchester, N Dawson, B Morris Nature reviews Drug discovery 11 (7), 560-579, 2012 | 201 | 2012 |
Subanaesthetic ketamine treatment alters prefrontal cortex connectivity with thalamus and ascending subcortical systems N Dawson, BJ Morris, JA Pratt Schizophrenia bulletin 39 (2), 366-377, 2013 | 106 | 2013 |
Glutamatergic regulation of cognition and functional brain connectivity: insights from pharmacological, genetic and translational schizophrenia research MR Dauvermann, G Lee, N Dawson British journal of pharmacology 174 (19), 3136-3160, 2017 | 85 | 2017 |
Sustained NMDA receptor hypofunction induces compromised neural systems integration and schizophrenia-like alterations in functional brain networks N Dawson, X Xiao, M McDonald, DJ Higham, BJ Morris, JA Pratt Cerebral cortex 24 (2), 452-464, 2014 | 67 | 2014 |
Modafinil reverses phencyclidine-induced deficits in cognitive flexibility, cerebral metabolism, and functional brain connectivity N Dawson, RJ Thompson, A McVie, DM Thomson, BJ Morris, JA Pratt Schizophrenia bulletin 38 (3), 457-474, 2012 | 59 | 2012 |
Alternating Hemiplegia of Childhood-Related Neural and Behavioural Phenotypes in Na+, K+-ATPase α3 Missense Mutant Mice GS Kirshenbaum, N Dawson, JGL Mullins, TH Johnston, MJ Drinkhill, ... PLOS ONE 8 (3), e60141, 2013 | 50 | 2013 |
Altered functional brain network connectivity and glutamate system function in transgenic mice expressing truncated Disrupted-in-Schizophrenia 1 N Dawson, M Kurihara, DM Thomson, CL Winchester, A McVie, JR Hedde, ... Translational psychiatry 5 (5), e569-e569, 2015 | 47 | 2015 |
Chronic, intermittent treatment with a cannabinoid receptor agonist impairs recognition memory and brain network functional connectivity FM Mouro, JA Ribeiro, AM Sebastião, N Dawson Journal of neurochemistry 147 (1), 71-83, 2018 | 39 | 2018 |
Subanesthetic ketamine treatment promotes abnormal interactions between neural subsystems and alters the properties of functional brain networks N Dawson, M McDonald, DJ Higham, BJ Morris, JA Pratt Neuropsychopharmacology 39 (7), 1786-1798, 2014 | 37 | 2014 |
Thalamo-cortical communication, glutamatergic neurotransmission and neural oscillations: A unique window into the origins of ScZ? J Pratt, N Dawson, BJ Morris, T Grent, F Roux, PJ Uhlhaas Schizophrenia research 180, 4-12, 2017 | 32 | 2017 |
Exploring metabolic pathway disruption in the subchronic phencyclidine model of schizophrenia with the Generalized Singular Value Decomposition X Xiao, N Dawson, L MacIntyre, BJ Morris, JA Pratt, DG Watson, ... BMC Systems Biology 5, 1-20, 2011 | 32 | 2011 |
16p11 duplication disrupts hippocampal-orbitofrontal-amygdala connectivity, revealing a neural circuit endophenotype for schizophrenia GC Bristow, DM Thomson, RL Openshaw, EJ Mitchell, JA Pratt, N Dawson, ... Cell reports 31 (3), 2020 | 31 | 2020 |
Functional brain connectivity phenotypes for schizophrenia drug discovery N Dawson, BJ Morris, JA Pratt Journal of psychopharmacology 29 (2), 169-177, 2015 | 22 | 2015 |
Sex influences the effect of a lifelong increase in serotonin transporter function on cerebral metabolism N Dawson, L Ferrington, HJ Olverman, AJ Harmar, PAT Kelly Journal of neuroscience research 87 (10), 2375-2385, 2009 | 19 | 2009 |
Cerebral metabolic responses to 5-HT2A/C receptor activation in mice with genetically modified serotonin transporter (SERT) expression N Dawson, L Ferrington, KP Lesch, PAT Kelly European Neuropsychopharmacology 21 (1), 117-128, 2011 | 18 | 2011 |
Deconstructing schizophrenia: advances in preclinical models for biomarker identification JA Pratt, B Morris, N Dawson Biomarkers in Psychiatry, 295-323, 2018 | 17 | 2018 |
Ketamine restores thalamic-prefrontal cortex functional connectivity in a mouse model of neurodevelopmental disorder-associated 2p16. 3 deletion R B Hughes, J Whittingham-Dowd, RE Simmons, SJ Clapcote, ... Cerebral Cortex 30 (4), 2358-2371, 2020 | 16 | 2020 |
Novel analysis for improved validity in semi-quantitative 2-deoxyglucose autoradiographic imaging N Dawson, L Ferrington, HJ Olverman, PAT Kelly Journal of neuroscience methods 175 (1), 25-35, 2008 | 16 | 2008 |
Sustained NMDA receptor hypofunction impairs brain-derived neurotropic factor signalling in the PFC, but not in the hippocampus, and disturbs PFC-dependent cognition in mice SR Tanqueiro, FM Mouro, CB Ferreira, CF Freitas, J Fonseca-Gomes, ... Journal of Psychopharmacology 35 (6), 730-743, 2021 | 15 | 2021 |
Drug-responsive autism phenotypes in the 16p11. 2 deletion mouse model: a central role for gene-environment interactions EJ Mitchell, DM Thomson, RL Openshaw, GC Bristow, N Dawson, JA Pratt, ... Scientific Reports 10 (1), 12303, 2020 | 13 | 2020 |