| Cancer stem cells: targeting the roots of cancer, seeds of metastasis, and sources of therapy resistance V Adorno-Cruz, G Kibria, X Liu, M Doherty, DJ Junk, D Guan, C Hubert, ... Cancer research 75 (6), 924-929, 2015 | 250 | 2015 |
| Diet-induced circadian enhancer remodeling synchronizes opposing hepatic lipid metabolic processes D Guan, Y Xiong, PC Borck, C Jang, PT Doulias, R Papazyan, B Fang, ... Cell 174 (4), 831-842. e12, 2018 | 160 | 2018 |
| The hepatocyte clock and feeding control chronophysiology of multiple liver cell types D Guan, Y Xiong, TM Trinh, Y Xiao, W Hu, C Jiang, P Dierickx, C Jang, ... Science 369 (6509), 1388-1394, 2020 | 113 | 2020 |
| The function, regulation and therapeutic implications of the tumor suppressor protein, PML D Guan, HY Kao Cell & bioscience 5, 1-14, 2015 | 99 | 2015 |
| Interconnections between circadian clocks and metabolism D Guan, MA Lazar The Journal of clinical investigation 131 (15), 2021 | 84 | 2021 |
| The epigenetic regulator UHRF1 promotes ubiquitination-mediated degradation of the tumor-suppressor protein promyelocytic leukemia protein D Guan, D Factor, Y Liu, Z Wang, HY Kao Oncogene 32 (33), 3819-3828, 2013 | 78 | 2013 |
| The hepatic circadian clock fine-tunes the lipogenic response to feeding through RORα/γ Y Zhang, R Papazyan, M Damle, B Fang, J Jager, D Feng, LC Peed, ... Genes & Development 31 (12), 1202-1211, 2017 | 70 | 2017 |
| HSP70 protein promotes survival of C6 and U87 glioma cells by inhibition of ATF5 degradation G Li, Y Xu, D Guan, Z Liu, DX Liu Journal of Biological Chemistry 286 (23), 20251-20259, 2011 | 70 | 2011 |
| HNF6 and Rev-erbα integrate hepatic lipid metabolism by overlapping and distinct transcriptional mechanisms Y Zhang, B Fang, M Damle, D Guan, Z Li, YH Kim, M Gannon, MA Lazar Genes & development 30 (14), 1636-1644, 2016 | 62 | 2016 |
| Deacetylation of the tumor suppressor protein PML regulates hydrogen peroxide-induced cell death D Guan, JH Lim, L Peng, Y Liu, M Lam, E Seto, HY Kao Cell death & disease 5 (7), e1340-e1340, 2014 | 44 | 2014 |
| N‐acetyl cysteine and penicillamine induce apoptosis via the ER stress response‐signaling pathway D Guan, Y Xu, M Yang, H Wang, X Wang, Z Shen Molecular Carcinogenesis: Published in cooperation with the University of …, 2010 | 41 | 2010 |
| Translational control of PML contributes to TNFα-induced apoptosis of MCF7 breast cancer cells and decreased angiogenesis in HUVECs KS Hsu, BJ Guan, X Cheng, D Guan, M Lam, M Hatzoglou, HY Kao Cell Death & Differentiation 23 (3), 469-483, 2016 | 37 | 2016 |
| Dual regulation of Stat1 and Stat3 by the tumor suppressor protein PML contributes to interferon α-mediated inhibition of angiogenesis KS Hsu, X Zhao, X Cheng, D Guan, GH Mahabeleshwar, Y Liu, E Borden, ... Journal of Biological Chemistry 292 (24), 10048-10060, 2017 | 36 | 2017 |
| N‐glycosylation of ATF6β is essential for its proteolytic cleavage and transcriptional repressor function to ATF6α D Guan, H Wang, VE Li, Y Xu, M Yang, Z Shen Journal of cellular biochemistry 108 (4), 825-831, 2009 | 34 | 2009 |
| Identification of a novel LXXLL motif in α-actinin 4-spliced isoform that is critical for its interaction with estrogen receptor α and co-activators S Khurana, S Chakraborty, X Zhao, Y Liu, D Guan, M Lam, W Huang, ... Journal of Biological Chemistry 287 (42), 35418-35429, 2012 | 32 | 2012 |
| Patient adipose stem cell-derived adipocytes reveal genetic variation that predicts antidiabetic drug response W Hu, C Jiang, D Guan, P Dierickx, R Zhang, A Moscati, GN Nadkarni, ... Cell Stem Cell 24 (2), 299-308. e6, 2019 | 30 | 2019 |
| Involvement of the role of Chk1 in lithium‐induced G2/M phase cell cycle arrest in hepatocellular carcinoma cells XM Wang, J Li, XC Feng, Q Wang, DY Guan, ZH Shen Journal of cellular biochemistry 104 (4), 1181-1191, 2008 | 27 | 2008 |
| Isoform-specific functions of PPARγ in gene regulation and metabolism W Hu, C Jiang, M Kim, Y Xiao, HJ Richter, D Guan, K Zhu, BM Krusen, ... Genes & Development 36 (5-6), 300-312, 2022 | 21 | 2022 |
| Nighttime light exposure enhances Rev-erbα-targeting microRNAs and contributes to hepatic steatosis PC Borck, TM Batista, JF Vettorazzi, GM Soares, C Lubaczeuski, D Guan, ... Metabolism 85, 250-258, 2018 | 21 | 2018 |
| Individual-specific functional epigenomics reveals genetic determinants of adverse metabolic effects of glucocorticoids W Hu, C Jiang, M Kim, W Yang, K Zhu, D Guan, W Lv, Y Xiao, JR Wilson, ... Cell metabolism 33 (8), 1592-1609. e7, 2021 | 18 | 2021 |
Xiaoming WangDuke University在 duke.edu 的电子邮件经过验证
Xiaoming WangDuke University在 duke.edu 的电子邮件经过验证
Zhenghe WangDepartment of Genetics, Case Western Reserve University在 case.edu 的电子邮件经过验证