Insights into the activation mechanism of class I HDAC complexes by inositol phosphates PJ Watson, CJ Millard, AM Riley, NS Robertson, LC Wright, HY Godage, ... Nature communications 7, 11262, 2016 | 222 | 2016 |
Histone deacetylase (HDAC) 1 and 2 complexes regulate both histone acetylation and crotonylation in vivo RDW Kelly, A Chandru, PJ Watson, Y Song, M Blades, NS Robertson, ... Scientific reports 8 (1), 14690, 2018 | 113 | 2018 |
Peptide Scanning for Studying Structure‐Activity Relationships in Drug Discovery AG Jamieson, N Boutard, D Sabatino, WD Lubell Chemical biology & drug design 81 (1), 148-165, 2013 | 105 | 2013 |
Positional scanning for peptide secondary structure by systematic solid-phase synthesis of amino lactam peptides AG Jamieson, N Boutard, K Beauregard, MS Bodas, H Ong, C Quiniou, ... Journal of the American Chemical Society 131 (22), 7917-7927, 2009 | 84 | 2009 |
Ether-directed, stereoselective aza-claisen rearrangements: synthesis of the piperidine alkaloid, α-conhydrine AG Jamieson, A Sutherland Organic letters 9 (8), 1609-1611, 2007 | 74 | 2007 |
Stereoselective β-hydroxy-α-amino acid synthesis via an ether-directed, palladium-catalysed aza-Claisen rearrangement KN Fanning, AG Jamieson, A Sutherland Organic & biomolecular chemistry 3 (20), 3749-3756, 2005 | 72 | 2005 |
A heme-binding domain controls regulation of ATP-dependent potassium channels MJ Burton, SM Kapetanaki, T Chernova, AG Jamieson, P Dorlet, ... Proceedings of the National Academy of Sciences 113 (14), 3785-3790, 2016 | 69 | 2016 |
Validation of the protein kinase PfCLK3 as a multi-stage cross species malarial drug target M Alam, A Sanchez-Azqueta, O Janha, E Flannery, A Mahindra, ... bioRxiv, 404459, 2018 | 66 | 2018 |
Insights into the recruitment of class IIa histone deacetylases (HDACs) to the SMRT/NCoR transcriptional repression complex GM Hudson, P Watson, L Fairall, A Jamieson, JWR Schwabe Journal of Biological Chemistry, jbc. M115. 661058, 2015 | 64 | 2015 |
A highly stereoselective ether directed palladium catalysed aza-Claisen rearrangement AG Jamieson, A Sutherland Organic & biomolecular chemistry 3 (5), 735-736, 2005 | 49 | 2005 |
Scope and limitations of ether-directed, metal-catalysed aza-Claisen rearrangements; improved stereoselectivity using non-coordinating solvents AG Jamieson, A Sutherland Organic & biomolecular chemistry 4 (15), 2932-2937, 2006 | 44 | 2006 |
The first enantioselective synthesis of the amino acid,(2S, 3S, 4R)-γ-hydroxyisoleucine using a palladium (II) catalysed 3, 3-sigmatropic rearrangement AG Jamieson, A Sutherland, CL Willis Organic & biomolecular chemistry 2 (6), 808-809, 2004 | 38 | 2004 |
Palladium (II)-catalysed rearrangement reactions KN Fanning, AG Jamieson, A Sutherland Current Organic Chemistry 10 (9), 1007-1020, 2006 | 37 | 2006 |
Regulation of protein–protein interactions using stapled peptides A Jamieson, NS Robertson | 36* | 2018 |
Ether-directed palladium (II)-catalysed aza-Claisen rearrangements: studies on the origin of the directing effect AG Jamieson, A Sutherland Tetrahedron 63 (10), 2123-2131, 2007 | 35 | 2007 |
Structure–Activity Analysis of the Growth Hormone Secretagogue GHRP‐6 by α‐and β‐Amino γ‐Lactam Positional Scanning N Boutard, AG Jamieson, H Ong, WD Lubell Chemical biology & drug design 75 (1), 40-50, 2010 | 34 | 2010 |
Solid-Phase Synthesis of Oxetane Modified Peptides JD Beadle, A Knuhtsen, A Hoose, P Raubo, AG Jamieson, M Shipman Organic letters 19 (12), 3303-3306, 2017 | 32 | 2017 |
A 1, 3-phenyl-linked hydantoin oligomer scaffold as a β-strand mimetic AG Jamieson, D Russell, AD Hamilton Chemical Communications 48 (31), 3709-3711, 2012 | 31 | 2012 |
A TPX2 proteomimetic has enhanced affinity for Aurora-A due to hydrocarbon stapling of a helix YK Rennie, PJ McIntyre, T Akindele, R Bayliss, AG Jamieson ACS chemical biology 11 (12), 3383-3390, 2016 | 30 | 2016 |
Robust asymmetric synthesis of unnatural alkenyl amino acids for conformationally constrained α-helix peptides B Aillard, NS Robertson, AR Baldwin, S Robins, AG Jamieson Organic & biomolecular chemistry 12 (43), 8775-8782, 2014 | 29 | 2014 |