Synergistic and low adverse effect cancer immunotherapy by immunogenic chemotherapy and locally expressed PD-L1 trap W Song, L Shen, Y Wang, Q Liu, TJ Goodwin, J Li, O Dorosheva, T Liu, ... Nature communications 9 (1), 2237, 2018 | 357 | 2018 |
Quercetin remodels the tumor microenvironment to improve the permeation, retention, and antitumor effects of nanoparticles K Hu, L Miao, TJ Goodwin, J Li, Q Liu, L Huang ACS nano 11 (5), 4916-4925, 2017 | 245 | 2017 |
Hepatoma-intrinsic CCRK inhibition diminishes myeloid-derived suppressor cell immunosuppression and enhances immune-checkpoint blockade efficacy J Zhou, M Liu, H Sun, Y Feng, L Xu, AWH Chan, JH Tong, J Wong, ... Gut 67 (5), 931-944, 2018 | 181 | 2018 |
Facile fabrication of tumor redox‐sensitive nanoassemblies of small‐molecule oleate prodrug as potent chemotherapeutic nanomedicine C Luo, J Sun, B Sun, D Liu, L Miao, TJ Goodwin, L Huang, Z He Small 12 (46), 6353-6362, 2016 | 155 | 2016 |
Transient and local expression of chemokine and immune checkpoint traps to treat pancreatic cancer L Miao, J Li, Q Liu, R Feng, M Das, CM Lin, TJ Goodwin, O Dorosheva, ... ACS nano 11 (9), 8690-8706, 2017 | 128 | 2017 |
Local blockade of interleukin 10 and CXC motif chemokine ligand 12 with nano-delivery promotes antitumor response in murine cancers L Shen, J Li, Q Liu, W Song, X Zhang, K Tiruthani, H Hu, M Das, ... ACS nano 12 (10), 9830-9841, 2018 | 119 | 2018 |
Local and transient gene expression primes the liver to resist cancer metastasis T Goodwin, Y Zhou, S Musetti, R Liu, L Huang Science Translational Medicine 8 (364), 364ra153, 2016 | 81 | 2016 |
Nanoparticle delivery of RIG-I agonist enables effective and safe adjuvant therapy in pancreatic cancer M Das, L Shen, Q Liu, TJ Goodwin, L Huang Molecular Therapy 27 (3), 507-517, 2019 | 79 | 2019 |
Investigation of phosphorylated adjuvants co-encapsulated with a model cancer peptide antigen for the treatment of colorectal cancer and liver metastasis TJ Goodwin, L Huang Vaccine 35 (19), 2550-2557, 2017 | 71 | 2017 |
Liver specific gene immunotherapies resolve immune suppressive ectopic lymphoid structures of liver metastases and prolong survival TJ Goodwin, L Shen, M Hu, J Li, R Feng, O Dorosheva, R Liu, L Huang Biomaterials 141, 260-271, 2017 | 54 | 2017 |
Nonviral vectors: we have come a long way T Goodwin, L Huang Advances in genetics 88, 1-12, 2014 | 46 | 2014 |
A circle RNA regulatory axis promotes lung squamous metastasis via CDR1-mediated regulation of Golgi trafficking EB Harrison, A Porrello, BM Bowman, AR Belanger, G Yacovone, ... Cancer research 80 (22), 4972-4985, 2020 | 26 | 2020 |
Targeting the hepatitis B cccDNA with a sequence-specific ARCUS nuclease to eliminate hepatitis B virus in vivo CL Gorsuch, P Nemec, M Yu, S Xu, D Han, J Smith, J Lape, N van Buuren, ... Molecular Therapy 30 (9), 2909-2922, 2022 | 21 | 2022 |
Glycoconjugated site-selective DNA-methylating agent targeting glucose transporters on glioma cells MK Buchanan, CN Needham, NE Neill, MC White, CB Kelly, ... Biochemistry 56 (2), 421-440, 2017 | 15 | 2017 |
On the article" Findings questioning the involvement of Sigma-1 receptor in the uptake of anisamide-decorated particles"[J. Control. Release 224 (2016) 229-238]: Letter to the … TJ Goodwin, L Huang Journal of controlled release: official journal of the Controlled Release …, 2016 | 13 | 2016 |
Nonviral Vectors for Gene Therapy: Lipid-and Polymer-based Gene Transfer L Huang, D Liu, E Wagner Academic Press, 2014 | 8 | 2014 |
HDAC8 inhibition modulates liver tumor microenvironment: Rationale for combined epigenetic and immunotherapy AS Cheng, Y Feng, J Zhou, W Yang, H Sun, Z Chen, T Goodwin, R Liu, ... The Journal of Immunology 198 (1_Supplement), 76.26-76.26, 2017 | 6 | 2017 |
A Gene Editing Approach to Eliminate Hepatitis B Virus Using ARCUS Meganucleases C Gorsuch, M Yu, S Xu, J Lape, T Goodwin, N Leatherbury, J Smith, ... MOLECULAR THERAPY 28 (4), 457-458, 2020 | 2 | 2020 |
Methods and Compositions for Reducing Metastases L Huang, T Goodwin, R Liu, L Miao US Patent App. 15/763,065, 2019 | 1 | 2019 |
Methods and compositions for reducing metastases L Huang, T GOODWIN, R Liu, L Miao | 1 | 2017 |