Structural basis of omalizumab therapy and omalizumab-mediated IgE exchange LF Pennington, S Tarchevskaya, D Brigger, K Sathiyamoorthy, ... Nature communications 7 (1), 11610, 2016 | 110 | 2016 |
Accuracy of serological testing for SARS‐CoV‐2 antibodies: first results of a large mixed‐method evaluation study D Brigger, MP Horn, LF Pennington, AE Powell, D Siegrist, B Weber, ... Allergy 76 (3), 853-865, 2021 | 38 | 2021 |
H-IPSE is a pathogen-secreted host nucleus-infiltrating protein (infiltrin) expressed exclusively by the Schistosoma haematobium egg stage LF Pennington, A Alouffi, EC Mbanefo, D Ray, DM Heery, TS Jardetzky, ... Infection and Immunity 85 (12), 10.1128/iai. 00301-17, 2017 | 37 | 2017 |
Structure-guided design of ultrapotent disruptive IgE inhibitors to rapidly terminate acute allergic reactions LF Pennington, P Gasser, D Brigger, P Guntern, A Eggel, TS Jardetzky Journal of Allergy and Clinical Immunology 148 (4), 1049-1060, 2021 | 29 | 2021 |
The soluble isoform of human Fcɛ RI is an endogenous inhibitor of IgE‐mediated mast cell responses S Moñino‐Romero, L Erkert, K Schmidthaler, SC Diesner, BF Sallis, ... Allergy 74 (2), 236-245, 2019 | 25 | 2019 |
Therapeutic exploitation of IPSE, a urogenital parasite-derived host modulatory protein, for chemotherapy-induced hemorrhagic cystitis EC Mbanefo, L Le, LF Pennington, JI Odegaard, TS Jardetzky, A Alouffi, ... The FASEB Journal 32 (8), 4408, 2018 | 22 | 2018 |
A new mouse model for female genital schistosomiasis ML Richardson, CL Fu, LF Pennington, JD Honeycutt, JL Odegaard, ... PLoS Neglected Tropical Diseases 8 (5), e2825, 2014 | 19 | 2014 |
IPSE, a urogenital parasite-derived immunomodulatory protein, ameliorates ifosfamide-induced hemorrhagic cystitis through downregulation of pro-inflammatory pathways EC Mbanefo, L Le, R Zee, N Banskota, K Ishida, LF Pennington, ... Scientific Reports 9 (1), 1586, 2019 | 17 | 2019 |
IPSE, an abundant egg-secreted protein of the carcinogenic helminth Schistosoma haematobium, promotes proliferation of bladder cancer cells and angiogenesis EC Mbanefo, CT Agbo, Y Zhao, OK Lamanna, KH Thai, SE Karinshak, ... Infectious Agents and Cancer 15, 1-10, 2020 | 15 | 2020 |
Immune response to parasitic infections LF Pennington, MH Hsieh Bentham ebooks 2, 93-124, 2014 | 9 | 2014 |
IPSE, a parasite-derived host immunomodulatory protein, is a potential therapeutic for hemorrhagic cystitis RS Zee, EC Mbanefo, LH Le, LF Pennington, JI Odegaard, TS Jardetzky, ... American Journal of Physiology-Renal Physiology 316 (6), F1133-F1140, 2019 | 8 | 2019 |
Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex LF Pennington, P Gasser, S Kleinboelting, C Zhang, G Skiniotis, A Eggel, ... Nature Communications 12 (1), 7069, 2021 | 7 | 2021 |
IPSE, a urogenital parasite-derived immunomodulatory molecule, suppresses bladder pathogenesis and anti-microbial peptide gene expression in bacterial urinary tract infection EC Mbanefo, L Le, LF Pennington, YJ Hsieh, JI Odegaard, K Lapira, ... Parasites & Vectors 13, 1-11, 2020 | 4 | 2020 |
SLAP deficiency decreases dsDNA autoantibody production LK Peterson, LF Pennington, LA Shaw, M Brown, EC Treacy, SF Friend, ... Clinical Immunology 150 (2), 201-209, 2014 | 4 | 2014 |
Sex-specific differences in immune response to SARS-CoV-2 vaccination vanish with age. D Brigger, PM Guntern, HR Jonsdottir, LF Pennington, B Weber, ... Allergy 78 (6), 1683-1686, 2023 | 3 | 2023 |
Structural basis of omalizumab therapy and omalizumab-mediated IgE exchange. Nat Commun. 2016; 7: 11610 LF Pennington, S Tarchevskaya, D Brigger, K Sathiyamoorthy, ... | 3 | |
IPSE, a parasite-derived, host Immunomodulatory Infiltrin protein, alleviates Resiniferatoxin-induced bladder pain K Ishida, EC Mbanefo, L Le, O Lamanna, LF Pennington, JC Finkel, ... Molecular Pain 16, 1744806920970099, 2020 | 2 | 2020 |
The immunobiology of urogenital schistosomiasis LF Pennington, MH Hsieh Immunity to Helminths and Novel Therapeutic Approaches 2, 93-124, 2014 | 2 | 2014 |
Omalizumab resistant IgE variants and their use in anti-IgE therapy TS Jardetzky, L Pennington US Patent App. 15/759,188, 2018 | 1 | 2018 |
Therapeutic monoclonal antibodies in allergy: Targeting IgE, cytokine, and alarmin pathways A Eggel, LF Pennington, TS Jardetzky Immunological reviews, 2024 | | 2024 |