Ferroptosis: a regulated cell death nexus linking metabolism, redox biology, and disease BR Stockwell, JPF Angeli, H Bayir, AI Bush, M Conrad, SJ Dixon, S Fulda, ... Cell 171 (2), 273-285, 2017 | 4940 | 2017 |
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice JP Friedmann Angeli, M Schneider, B Proneth, YY Tyurina, VA Tyurin, ... Nature cell biology 16 (12), 1180-1191, 2014 | 2698 | 2014 |
ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition S Doll, B Proneth, YY Tyurina, E Panzilius, S Kobayashi, I Ingold, M Irmler, ... Nature chemical biology 13 (1), 91-98, 2017 | 2509 | 2017 |
FSP1 is a glutathione-independent ferroptosis suppressor S Doll, FP Freitas, R Shah, M Aldrovandi, MC da Silva, I Ingold, ... Nature 575 (7784), 693-698, 2019 | 1961 | 2019 |
Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis VE Kagan, G Mao, F Qu, JPF Angeli, S Doll, CS Croix, HH Dar, B Liu, ... Nature chemical biology 13 (1), 81-90, 2017 | 1922 | 2017 |
Selenium utilization by GPX4 is required to prevent hydroperoxide-induced ferroptosis I Ingold, C Berndt, S Schmitt, S Doll, G Poschmann, K Buday, A Roveri, ... Cell 172 (3), 409-422. e21, 2018 | 1100 | 2018 |
Ferroptosis at the crossroads of cancer-acquired drug resistance and immune evasion JP Friedmann Angeli, DV Krysko, M Conrad Nature Reviews Cancer 19 (7), 405-414, 2019 | 866 | 2019 |
On the mechanism of cytoprotection by ferrostatin-1 and liproxstatin-1 and the role of lipid peroxidation in ferroptotic cell death O Zilka, R Shah, B Li, JP Friedmann Angeli, M Griesser, M Conrad, ... ACS central science 3 (3), 232-243, 2017 | 712 | 2017 |
Regulated necrosis: disease relevance and therapeutic opportunities M Conrad, JPF Angeli, P Vandenabeele, BR Stockwell Nature reviews Drug discovery 15 (5), 348-366, 2016 | 626 | 2016 |
Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma B Hassannia, B Wiernicki, I Ingold, F Qu, S Van Herck, YY Tyurina, ... The Journal of clinical investigation 128 (8), 3341-3355, 2018 | 488 | 2018 |
Ferroptosis inhibition: mechanisms and opportunities JPF Angeli, R Shah, DA Pratt, M Conrad Trends in pharmacological sciences 38 (5), 489-498, 2017 | 466 | 2017 |
β-Glucans in promoting health: Prevention against mutation and cancer MS Mantovani, MF Bellini, JPF Angeli, RJ Oliveira, AF Silva, LR Ribeiro Mutation Research/Reviews in Mutation Research 658 (3), 154-161, 2008 | 370 | 2008 |
Identification and successful negotiation of a metabolic checkpoint in direct neuronal reprogramming S Gascón, E Murenu, G Masserdotti, F Ortega, GL Russo, D Petrik, ... Cell stem cell 18 (3), 396-409, 2016 | 348 | 2016 |
Genotoxic, mutagenic and cytotoxic effects of the commercial dye CI Disperse Blue 291 in the human hepatic cell line HepG2 MS Tsuboy, JPF Angeli, MS Mantovani, S Knasmüller, GA Umbuzeiro, ... Toxicology in vitro 21 (8), 1650-1655, 2007 | 237 | 2007 |
Glutathione peroxidase 4 (Gpx4) and ferroptosis: what's so special about it? M Conrad, JP Friedmann Angeli Molecular & cellular oncology 2 (3), e995047, 2015 | 168 | 2015 |
Quantitative profiling of protein carbonylations in ferroptosis by an aniline-derived probe Y Chen, Y Liu, T Lan, W Qin, Y Zhu, K Qin, J Gao, H Wang, X Hou, ... Journal of the American Chemical Society 140 (13), 4712-4720, 2018 | 161 | 2018 |
The azo dyes Disperse Red 1 and Disperse Orange 1 increase the micronuclei frequencies in human lymphocytes and in HepG2 cells FMD Chequer, JPF Angeli, ERA Ferraz, MS Tsuboy, JC Marcarini, ... Mutation Research/Genetic Toxicology and Environmental Mutagenesis 676 (1-2 …, 2009 | 161 | 2009 |
Selenium and GPX4, a vital symbiosis JPF Angeli, M Conrad Free Radical Biology and Medicine 127, 153-159, 2018 | 149 | 2018 |
Activation of glutathione peroxidase 4 as a novel anti-inflammatory strategy C Li, X Deng, X Xie, Y Liu, JP Friedmann Angeli, L Lai Frontiers in pharmacology 9, 385435, 2018 | 130 | 2018 |
Hydropersulfides inhibit lipid peroxidation and ferroptosis by scavenging radicals U Barayeu, D Schilling, M Eid, TN Xavier da Silva, L Schlicker, N Mitreska, ... Nature chemical biology 19 (1), 28-37, 2023 | 105 | 2023 |