The emerging role of cell-free DNA as a molecular marker for cancer management AJ Bronkhorst, V Ungerer, S Holdenrieder Biomolecular detection and quantification 17, 100087, 2019 | 499 | 2019 |
The diverse origins of circulating cell‐free DNA in the human body: a critical re‐evaluation of the literature J Aucamp, AJ Bronkhorst, CPS Badenhorst, PJ Pretorius Biological Reviews 93 (3), 1649-1683, 2018 | 313 | 2018 |
Characterization of the cell-free DNA released by cultured cancer cells AJ Bronkhorst, JF Wentzel, J Aucamp, E Van Dyk, L Du Plessis, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (1), 157-165, 2016 | 204 | 2016 |
Cell-free DNA: preanalytical variables AJ Bronkhorst, J Aucamp, PJ Pretorius Clinica Chimica Acta 450, 243-253, 2015 | 187 | 2015 |
Putative origins of cell-free DNA in humans: a review of active and passive nucleic acid release mechanisms S Grabuschnig, AJ Bronkhorst, S Holdenrieder, I Rosales Rodriguez, ... International journal of molecular sciences 21 (21), 8062, 2020 | 168 | 2020 |
Harmonizing cell-free DNA collection and processing practices through evidence-based guidance SR Greytak, KB Engel, S Parpart-Li, M Murtaza, AJ Bronkhorst, MD Pertile, ... Clinical Cancer Research 26 (13), 3104-3109, 2020 | 97 | 2020 |
Preanalytical variables that affect the outcome of cell-free DNA measurements V Ungerer, AJ Bronkhorst, S Holdenrieder Critical Reviews in Clinical Laboratory Sciences 57 (7), 484-507, 2020 | 64 | 2020 |
Towards systematic nomenclature for cell-free DNA AJ Bronkhorst, V Ungerer, F Diehl, P Anker, Y Dor, M Fleischhacker, ... Human genetics 140, 565-578, 2021 | 62 | 2021 |
Exposure to high levels of fumarate and succinate leads to apoptotic cytotoxicity and altered global DNA methylation profiles in vitro JF Wentzel, A Lewies, AJ Bronkhorst, E Van Dyk, LH Du Plessis, ... Biochimie 135, 28-34, 2017 | 60 | 2017 |
Kinetic analysis, size profiling, and bioenergetic association of DNA released by selected cell lines in vitro J Aucamp, AJ Bronkhorst, DL Peters, HC Van Dyk, ... Cellular and Molecular Life Sciences 74, 2689-2707, 2017 | 50 | 2017 |
Early detection of cancer using circulating tumor DNA: biological, physiological and analytical considerations AJ Bronkhorst, V Ungerer, S Holdenrieder Critical reviews in clinical laboratory sciences 57 (4), 253-269, 2020 | 44 | 2020 |
Comparison of methods for the isolation of cell-free DNA from cell culture supernatant AJ Bronkhorst, V Ungerer, S Holdenrieder Tumor Biology 42 (4), 1010428320916314, 2020 | 43 | 2020 |
Sequence analysis of cell-free DNA derived from cultured human bone osteosarcoma (143B) cells AJ Bronkhorst, JF Wentzel, V Ungerer, DL Peters, J Aucamp, ... Tumor Biology 40 (9), 1010428318801190, 2018 | 42 | 2018 |
A historical and evolutionary perspective on the biological significance of circulating DNA and extracellular vesicles J Aucamp, AJ Bronkhorst, CPS Badenhorst, PJ Pretorius Cellular and Molecular Life Sciences 73, 4355-4381, 2016 | 42 | 2016 |
New perspectives on the importance of cell-free DNA biology AJ Bronkhorst, V Ungerer, A Oberhofer, S Gabriel, E Polatoglou, ... Diagnostics 12 (9), 2147, 2022 | 39 | 2022 |
Serial profiling of cell-free DNA and nucleosome histone modifications in cell cultures V Ungerer, AJ Bronkhorst, P Van den Ackerveken, M Herzog, ... Scientific reports 11 (1), 9460, 2021 | 38 | 2021 |
Comparison of methods for the quantification of cell-free DNA isolated from cell culture supernatant AJ Bronkhorst, V Ungerer, S Holdenrieder Tumor Biology 41 (8), 1010428319866369, 2019 | 34 | 2019 |
Histone modifications in stem cell development and their clinical implications M Völker-Albert, A Bronkhorst, S Holdenrieder, A Imhof Stem Cell Reports 15 (6), 1196-1205, 2020 | 28 | 2020 |
Tracing the origin of cell-Free DNA molecules through tissue-Specific epigenetic signatures A Oberhofer, AJ Bronkhorst, C Uhlig, V Ungerer, S Holdenrieder Diagnostics 12 (8), 1834, 2022 | 27 | 2022 |
The clinical utility of droplet digital PCR for profiling circulating tumor DNA in breast cancer patients U Gezer, AJ Bronkhorst, S Holdenrieder Diagnostics 12 (12), 3042, 2022 | 25 | 2022 |