Serum deprivation inhibits the transcriptional co-activator YAP and cell growth via phosphorylation of the 130-kDa isoform of Angiomotin by the LATS1/2 protein kinases JJ Adler, DE Johnson, BL Heller, LR Bringman, WP Ranahan, ... Proceedings of the National Academy of Sciences 110 (43), 17368-17373, 2013 | 164 | 2013 |
Primary cilia signaling mediates intraocular pressure sensation N Luo, MD Conwell, X Chen, CI Kettenhofen, CJ Westlake, LB Cantor, ... Proceedings of the National Academy of Sciences 111 (35), 12871-12876, 2014 | 129 | 2014 |
Inositol 1, 3, 4-trisphosphate 5/6-kinase associates with the COP9 signalosome by binding to CSN1 Y Sun, MP Wilson, PW Majerus Journal of Biological Chemistry 277 (48), 45759-45764, 2002 | 125 | 2002 |
Elevated vascular endothelial growth factor levels in Coats disease: rapid response to pegaptanib sodium Y Sun, A Jain, DM Moshfeghi Graefe's Archive for Clinical and Experimental Ophthalmology 245, 1387-1388, 2007 | 120 | 2007 |
OCRL localizes to the primary cilium: a new role for cilia in Lowe syndrome N Luo, CC West, CA Murga-Zamalloa, L Sun, RM Anderson, CD Wells, ... Human molecular genetics 21 (15), 3333-3344, 2012 | 119 | 2012 |
Inositol 1, 3, 4-trisphosphate 5/6-kinase is a protein kinase that phosphorylates the transcription factors c-Jun and ATF-2 MP Wilson, Y Sun, L Cao, PW Majerus Journal of Biological Chemistry 276 (44), 40998-41004, 2001 | 91 | 2001 |
Review of ocular manifestations of Joubert syndrome SF Wang, TJ Kowal, K Ning, EB Koo, AY Wu, VB Mahajan, Y Sun Genes 9 (12), 605, 2018 | 76 | 2018 |
Chloroquine promotes apoptosis in melanoma cells by inhibiting BH3 domain–mediated PUMA degradation AJ Lakhter, RP Sahu, Y Sun, WK Kaufmann, EJ Androphy, JB Travers, ... Journal of Investigative Dermatology 133 (9), 2247-2254, 2013 | 74 | 2013 |
Drug delivery to the anterior segment of the eye: A review of current and future treatment strategies M Mofidfar, B Abdi, S Ahadian, E Mostafavi, TA Desai, F Abbasi, Y Sun, ... International journal of pharmaceutics 607, 120924, 2021 | 70 | 2021 |
Functional analysis of the p53 pathway in response to ionizing radiation in uveal melanoma Y Sun, BN Tran, LA Worley, RB Delston, JW Harbour Investigative ophthalmology & visual science 46 (5), 1561-1564, 2005 | 61 | 2005 |
Silicone oil-induced ocular hypertension and glaucomatous neurodegeneration in mouse J Zhang, L Li, H Huang, F Fang, HC Webber, P Zhuang, L Liu, R Dalal, ... Elife 8, e45881, 2019 | 59 | 2019 |
Loss of OCRL increases ciliary PI(4,5)P2 in Lowe oculocerebrorenal syndrome PP Prosseda, N Luo, B Wang, JA Alvarado, Y Hu, Y Sun Journal of cell science 130 (20), 3447-3454, 2017 | 58 | 2017 |
Neuroprotection by eIF2α-CHOP inhibition and XBP-1 activation in EAE/optic neuritiss H Huang, L Miao, F Liang, X Liu, L Xu, X Teng, Q Wang, WH Ridder, ... Cell death & disease 8 (7), e2936-e2936, 2017 | 57 | 2017 |
Mouse γ-synuclein promoter-mediated gene expression and editing in mammalian retinal ganglion cells Q Wang, P Zhuang, H Huang, L Li, L Liu, HC Webber, R Dalal, L Siew, ... Journal of Neuroscience 40 (20), 3896-3914, 2020 | 56 | 2020 |
p38 phosphorylates Rb on Ser567 by a novel, cell cycle-independent mechanism that triggers Rb–Hdm2 interaction and apoptosis RB Delston, KA Matatall, Y Sun, MD Onken, JW Harbour Oncogene 30 (5), 588-599, 2011 | 53 | 2011 |
AKT-dependent and-independent pathways mediate PTEN deletion-induced CNS axon regeneration H Huang, L Miao, L Yang, F Liang, Q Wang, P Zhuang, Y Sun, Y Hu Cell death & disease 10 (3), 203, 2019 | 50 | 2019 |
Compensatory role of inositol 5-phosphatase INPP5B to OCRL in primary cilia formation in oculocerebrorenal syndrome of Lowe N Luo, A Kumar, M Conwell, RN Weinreb, R Anderson, Y Sun PLoS One 8 (6), e66727, 2013 | 50 | 2013 |
Evidence of a role of inositol polyphosphate 5-phosphatase INPP5E in cilia formation in zebrafish N Luo, J Lu, Y Sun Vision research 75, 98-107, 2012 | 47 | 2012 |
Longitudinal morphological and functional assessment of RGC neurodegeneration after optic nerve crush in mouse L Li, H Huang, F Fang, L Liu, Y Sun, Y Hu Frontiers in cellular neuroscience 14, 109, 2020 | 44 | 2020 |
Proteomic analysis of the human retina reveals region-specific susceptibilities to metabolic-and oxidative stress-related diseases G Velez, DA Machlab, PH Tang, Y Sun, SH Tsang, AG Bassuk, ... PLoS One 13 (2), e0193250, 2018 | 44 | 2018 |