Long-lasting antinociceptive effects of green light in acute and chronic pain in rats MM Ibrahim, A Patwardhan, KB Gilbraith, A Moutal, X Yang, LA Chew, ... Pain 158 (2), 347-360, 2017 | 104 | 2017 |
CRISPR/Cas9 editing of Nf1 gene identifies CRMP2 as a therapeutic target in neurofibromatosis type 1-related pain that is reversed by (S)-Lacosamide A Moutal, X Yang, W Li, KB Gilbraith, S Luo, S Cai, L François-Moutal, ... Pain 158 (12), 2301-2319, 2017 | 77 | 2017 |
(S)-lacosamide inhibition of CRMP2 phosphorylation reduces postoperative and neuropathic pain behaviors through distinct classes of sensory neurons identified by constellation … A Moutal, LA Chew, X Yang, Y Wang, SK Yeon, E Telemi, S Meroueh, ... Pain 157 (7), 1448-1463, 2016 | 63 | 2016 |
(S)-Lacosamide Binding to Collapsin Response Mediator Protein 2 (CRMP2) Regulates CaV2.2 Activity by Subverting Its Phosphorylation by Cdk5 A Moutal, L François-Moutal, S Perez-Miller, K Cottier, LA Chew, SK Yeon, ... Molecular neurobiology 53, 1959-1976, 2016 | 60 | 2016 |
Dissecting the role of the CRMP2–neurofibromin complex on pain behaviors A Moutal, Y Wang, X Yang, Y Ji, S Luo, A Dorame, SS Bellampalli, ... Pain 158 (11), 2203-2221, 2017 | 59 | 2017 |
Betulinic acid, derived from the desert lavender Hyptis emoryi, attenuates paclitaxel-, HIV-, and nerve injury–associated peripheral sensory neuropathy via block of N-and T … SS Bellampalli, Y Ji, A Moutal, S Cai, EMK Wijeratne, MA Gandini, J Yu, ... Pain 160 (1), 117-135, 2019 | 56 | 2019 |
CRMP2 and voltage-gated ion channels: potential roles in neuropathic pain LA Chew, R Khanna Neuronal Signaling 2 (1), NS20170220, 2018 | 44 | 2018 |
Targeting the CaVα–CaVβ interaction yields an antagonist of the N-type CaV2. 2 channel with broad antinociceptive efficacy R Khanna, J Yu, X Yang, A Moutal, A Chefdeville, V Gokhale, Z Shuja, ... Pain 160 (7), 1644-1661, 2019 | 38 | 2019 |
Studies on CRMP2 SUMOylation–deficient transgenic mice identify sex-specific Nav1. 7 regulation in the pathogenesis of chronic neuropathic pain A Moutal, S Cai, J Yu, HJ Stratton, A Chefdeville, K Gomez, D Ran, ... Pain 161 (11), 2629-2651, 2020 | 34 | 2020 |
Sustained relief of ongoing experimental neuropathic pain by a CRMP2 peptide aptamer with low abuse potential JY Xie, LA Chew, X Yang, Y Wang, C Qu, Y Wang, LM Federici, SD Fitz, ... Pain 157 (9), 2124-2140, 2016 | 33 | 2016 |
Mining the Nav1. 7 interactome: Opportunities for chronic pain therapeutics LA Chew, SS Bellampalli, ET Dustrude, R Khanna Biochemical pharmacology 163, 9-20, 2019 | 32 | 2019 |
Selective targeting of NaV1. 7 via inhibition of the CRMP2-Ubc9 interaction reduces pain in rodents S Cai, A Moutal, J Yu, LA Chew, J Isensee, R Chawla, K Gomez, S Luo, ... Science Translational Medicine 13 (619), eabh1314, 2021 | 26 | 2021 |
Development and characterization of an injury-free model of functional pain in rats by exposure to red light R Khanna, A Patwardhan, X Yang, W Li, S Cai, Y Ji, LA Chew, A Dorame, ... The journal of pain 20 (11), 1293-1306, 2019 | 22 | 2019 |
Chemotherapy can induce weight normalization of morbidly obese mice despite undiminished ingestion of high fat diet CE Myers, DB Hoelzinger, TN Truong, LA Chew, A Myles, L Chaudhuri, ... Oncotarget 8 (3), 5426, 2017 | 17 | 2017 |
Tetramethylpyrazine reduces epileptogenesis progression in electrical kindling models by modulating hippocampal excitatory neurotransmission Y Jin, S Cai, Y Jiang, K Zhong, C Wen, Y Ruan, LA Chew, R Khanna, Z Xu, ... ACS Chemical Neuroscience 10 (12), 4854-4863, 2019 | 16 | 2019 |
Conotoxin contulakin-G engages a neurotensin receptor 2/R-type calcium channel (Cav2. 3) pathway to mediate spinal antinociception L Martin, M Ibrahim, K Gomez, J Yu, S Cai, LA Chew, SS Bellampalli, ... Pain 163 (9), 1751-1762, 2022 | 13 | 2022 |
Robust cone-mediated signaling persists late into rod photoreceptor degeneration ML Scalabrino, M Thapa, LA Chew, E Zhang, J Xu, AP Sampath, J Chen, ... Elife 11, e80271, 2022 | 8 | 2022 |
Gene-agnostic approaches to treating inherited retinal degenerations LA Chew, A Iannaccone Frontiers in Cell and Developmental Biology 11, 1177838, 2023 | 4 | 2023 |
Microglia at Sites of Atrophy Restrict the Progression of Retinal Degeneration via Galectin-3 and Trem2 Interactions C Yu, EM Lad, R Mathew, S Littleton, Y Chen, K Schlepckow, S Degan, ... bioRxiv, 2023 | 3 | 2023 |
AAV gene augmentation of truncated complement factor h differentially rescues ocular complement dysregulation in a mouse model D Grigsby, M Klingeborn, U Kelly, LA Chew, A Asokan, G Devlin, S Smith, ... Investigative Ophthalmology & Visual Science 64 (10), 25-25, 2023 | 3 | 2023 |