Cysteine-aminoethylation-assisted chemical ubiquitination of recombinant histones GC Chu, M Pan, J Li, S Liu, C Zuo, ZB Tong, JS Bai, Q Gong, H Ai, J Fan, ... Journal of the American Chemical Society 141 (8), 3654-3663, 2019 | 86 | 2019 |
H2B Lys34 ubiquitination induces nucleosome distortion to stimulate Dot1L activity H Ai, M Sun, A Liu, Z Sun, T Liu, L Cao, L Liang, Q Qu, Z Li, Z Deng, ... Nature Chemical Biology 18 (9), 972-980, 2022 | 59 | 2022 |
Chemical synthesis of post-translationally modified H2AX reveals redundancy in interplay between histone phosphorylation, ubiquitination, and methylation on the binding of … H Ai, GC Chu, Q Gong, ZB Tong, Z Deng, X Liu, F Yang, Z Xu, JB Li, ... Journal of the American Chemical Society 144 (40), 18329-18337, 2022 | 35 | 2022 |
Synthetic E2-Ub-nucleosome conjugates for studying nucleosome ubiquitination H Ai, Z Tong, Z Deng, J Tian, L Zhang, M Sun, Y Du, Z Xu, Q Shi, L Liang, ... Chem 9 (5), 1221-1240, 2023 | 28 | 2023 |
Thioester‐Assisted Sortase‐A‐Mediated Ligation C Zuo, R Ding, X Wu, Y Wang, GC Chu, LJ Liang, H Ai, ZB Tong, J Mao, ... Angewandte Chemie 134 (28), e202201887, 2022 | 27 | 2022 |
The mechanism of chromatin remodeler SMARCAD1/Fun30 in response to DNA damage ZB Tong, HS Ai, JB Li Frontiers in Cell and Developmental Biology 8, 560098, 2020 | 10 | 2020 |
Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes MPLL Zebin Tong, Huasong Ai, Ziyu Xu, Kezhang He, Guo-Chao Chu, Qiang Shi ... Nature Structural&Molecular Biology, 2024 | 9 | 2024 |
Mechanistic insights into nucleosomal H2B monoubiquitylation mediated by yeast Bre1-Rad6 and its human homolog RNF20/RNF40-hRAD6A Z Deng, H Ai, M Sun, Z Tong, Y Du, Q Qu, L Zhang, Z Xu, S Tao, Q Shi, ... Molecular Cell 83 (17), 3080-3094. e14, 2023 | 9 | 2023 |
Structural visualization of HECT-E3 Ufd4 accepting and transferring ubiquitin to form K29/K48-branched polyubiquitination on N-degron J Mao, H Ai, X Wu, Q Zheng, H Cai, L Liang, Z Tong, M Pan, L Liu BioRxiv, 2023.05. 23.542033, 2023 | 8 | 2023 |
The expedient, CAET-assisted synthesis of dual-monoubiquitinated histone H3 enables evaluation of its interaction with DNMT1 Z Li, Z Tong, Q Gong, H Ai, S Peng, C Chen, GC Chu, JB Li Chemical Science 14 (21), 5681-5688, 2023 | 3 | 2023 |
Structural and mechanistic basis for nucleosomal H2AK119 deubiquitination by single-subunit deubiquitinase USP16 H Ai, Z He, Z Deng, GC Chu, Q Shi, Z Tong, JB Li, M Pan, L Liu Nature Structural & Molecular Biology, 1-11, 2024 | 1 | 2024 |
Capturing Snapshots of Nucleosomal H2A K13/K15 Ubiquitination Mediated by the Monomeric E3 Ligase RNF168 H Ai, Z Tong, Z Deng, Q Shi, S Tao, J Liang, M Sun, X Wei, Q Zheng, ... bioRxiv, 2024.01. 02.573964, 2024 | 1 | 2024 |
Sequential release of interacting proteins and Ub-modifying enzymes by disulfide heterotypic ubiquitin reagents H Cai, X Wu, J Mao, Z Tong, D Yan, Y Weng, Q Zheng Bioorganic Chemistry 145, 107186, 2024 | | 2024 |
Promotion of RNF168-Mediated Nucleosomal H2A Ubiquitylation by Structurally-defined K63-Polyubiquitylated Linker Histone H1 Q Shi, Z Deng, L Zhang, Z Tong, JB Li, GC Chu, H Ai, L Liu bioRxiv, 2024.07. 22.604500, 2024 | | 2024 |
Synovial 1 Sarcoma X Breakpoint Protein Uses a Cryptic Groove to Selectively Recognize H2AK119Ub Nucleosomes Z Tong, H Ai, Z Xu, K He, G Chu, Q Shi, Z Deng, Q Xue, M Sun, Y Du, ... bioRxiv, 2023.07. 08.548231, 2023 | | 2023 |