Signaling through ShcA is required for transforming growth factor β-and Neu/ErbB-2-induced breast cancer cell motility and invasion JJ Northey, J Chmielecki, E Ngan, C Russo, MG Annis, WJ Muller, ... Molecular and cellular biology 28 (10), 3162-3176, 2008 | 98 | 2008 |
Genetic and pharmacologic inhibition of eIF4E reduces breast cancer cell migration, invasion, and metastasis F Pettersson, SV Del Rincon, A Emond, B Huor, E Ngan, J Ng, ... Cancer research 75 (6), 1102-1112, 2015 | 88 | 2015 |
LPP is a Src substrate required for invadopodia formation and efficient breast cancer lung metastasis E Ngan, K Stoletov, HW Smith, J Common, WJ Muller, JD Lewis, ... Nature communications 8 (1), 15059, 2017 | 75 | 2017 |
A complex containing LPP and α-actinin mediates TGFβ-induced migration and invasion of ErbB2-expressing breast cancer cells E Ngan, JJ Northey, CM Brown, J Ursini-Siegel, PM Siegel J Cell Sci 126 (9), 1981-1991, 2013 | 58 | 2013 |
Distinct phosphotyrosine-dependent functions of the ShcA adaptor protein are required for transforming growth factor β (TGFβ)-induced breast cancer cell migration, invasion … JJ Northey, Z Dong, E Ngan, A Kaplan, WR Hardy, T Pawson, PM Siegel Journal of Biological Chemistry 288 (7), 5210-5222, 2013 | 32 | 2013 |
Distinct Phosphotyrosine-dependent Functions of the ShcA Adaptor Protein Are Required for Transforming Growth Factor β (TGFβ)-induced Breast Cancer Cell Migration, Invasion … JJ Northey, Z Dong, E Ngan, A Kaplan, WR Hardy, T Pawson, PM Siegel Journal of Biological Chemistry 288 (7), 5210-5222, 2013 | 32 | 2013 |
Emerging roles for LPP in metastatic cancer progression E Ngan, A Kiepas, CM Brown, PM Siegel Journal of cell communication and signaling 12, 143-156, 2018 | 31 | 2018 |
Real-World Study to Assess Patterns of Treatment Practices and Clinical Outcomes in Metastatic Colorectal Cancer Patients with RAS Wild-Type Left-Sided … DJ Boyne, E Ngan, C Carbonell, RJ Wani, C Cirone Morris, DJ Martinez, ... Current Oncology 30 (9), 8220-8232, 2023 | 2 | 2023 |
Real-World Safety and Effectiveness of a bevacizumab biosimilar (ABP 215) in Metastatic Colorectal Cancer Patients in Canada WY Cheung, S Samimi, K Ma, G Knight, S Kassam, B Colwell, A Beaudoin, ... Clinical Colorectal Cancer, 2023 | 1 | 2023 |
Real-world safety and effectiveness of MVASI in metastatic colorectal cancer patients in Canada. WY Cheung, S Samimi, K Ma, GJ Knight, SN Kassam, B Colwell, ... Journal of Clinical Oncology 41 (16_suppl), e15555-e15555, 2023 | | 2023 |
Real-world use of biologics and its association with outcomes in RAS wild-type (WT) left-sided metastatic colorectal cancer (mCRC) in Canada. WY Cheung, DJ Boyne, DR Brenner, D Martinez, RJ Wani, E Ngan Journal of Clinical Oncology 41 (4_suppl), 56-56, 2023 | | 2023 |
P-28 Real-world observational study of MVASI in metastatic colorectal cancer patients in Canada: Baseline patient characteristics W Cheung, S Samimi, S Kassam, B Colwell, P Meyer, G Knight, K Ma, ... Annals of Oncology 33, S257, 2022 | | 2022 |
LPP Promotes Breast Cancer Metastasis and is Required for Invadopodia formation E Ngan, K Stoletov, Z Dong, J Common, JD Lewis, PM Siegel Defining the pro-metastatic functions of LPP in breast cancer, 119, 2016 | | 2016 |
Src-mediated Phosphorylation of Distinct Tyrosine Residues within LPP is Critical for Breast Cancer Invasion E Ngan, HW Smith, WJ Muller, PM Siegel Defining the pro-metastatic functions of LPP in breast cancer, 168, 2016 | | 2016 |
Defining the pro-metastatic functions of LPP in breast cancer E Ngan McGill University (Canada), 2016 | | 2016 |
LPP promotes ErbB2 overexpressing breast cancer cell migration, invasion and metastasis E Ngan, PM Siegel Cancer Research 74 (19_Supplement), 2093-2093, 2014 | | 2014 |
TGF-beta induced epithelial-to-mesenchymal transition is attenuated when the MNK/eIF4E pathway is functionally impaired. SV del Rincon, B Huor, E Ngan, L Petruccelli, P Siegel, WH Miller Cancer Research 73 (8 Supplement), 288-288, 2013 | | 2013 |
Distinct phospho-tyrosine dependent functions of ShcA are required for TGFβ-induced breast cancer cell migration, invasion and metastasis JJ Northey, Z Dong, E Ngan, A Kaplan, WR Hardy, T Pawson, PM Siegel Journal of Biological Chemistry, jbc. M112. 424804, 2012 | | 2012 |
Breast cancer cells that undergo an Epithelial-to-Mesenchymal transition co-opt LPP, a regulator of mesenchymal cell migration and invasion. E Ngan, JJ Northey, J Ursini-Siegel, PM Siegel CANCER RESEARCH 72, 2012 | | 2012 |
Abstract P1-05-22: Breast cancer cells that undergo an Epithelial-to-Mesenchymal transition co-opt LPP, a regulator of mesenchymal cell migration and invasion. E Ngan, JJ Northey, J Ursini-Siegel, PM Siegel Cancer Research 72 (24_Supplement), P1-05-22-P1-05-22, 2012 | | 2012 |