Semi-rational approaches to engineering enzyme activity: combining the benefits of directed evolution and rational design RA Chica, N Doucet, JN Pelletier Current opinion in biotechnology 16 (4), 378-384, 2005 | 732 | 2005 |
Oligomerization domain-directed reassembly of active dihydrofolate reductase from rationally designed fragments JN Pelletier, FX Campbell-Valois, SW Michnick Proceedings of the National Academy of Sciences 95 (21), 12141-12146, 1998 | 507 | 1998 |
Expanding the organic toolbox: a guide to integrating biocatalysis in synthesis CM Clouthier, JN Pelletier Chemical Society Reviews 41 (4), 1585-1605, 2012 | 414 | 2012 |
An in vivo library-versus-library selection of optimized protein–protein interactions JN Pelletier, KM Arndt, A Plückthun, SW Michnick Nature biotechnology 17 (7), 683-690, 1999 | 265 | 1999 |
[14] Detection of protein-protein interactions by protein fragment complementation strategies SW Michnick, I Remy, FX Campbell-Valois, A Vallée-Bélisle, JN Pelletier Methods in enzymology 328, 208-230, 2000 | 183 | 2000 |
Protein motions promote catalysis A Tousignant, JN Pelletier Chemistry & biology 11 (8), 1037-1042, 2004 | 159 | 2004 |
Miniature multi-channel SPR instrument for methotrexate monitoring in clinical samples SS Zhao, N Bukar, JL Toulouse, D Pelechacz, R Robitaille, JN Pelletier, ... Biosensors and Bioelectronics 64, 664-670, 2015 | 155 | 2015 |
A heterodimeric coiled-coil peptide pair selected in vivo from a designed library-versus-library ensemble KM Arndt, JN Pelletier, KM MuÈller, T Alber, SW Michnick, A PluÈckthun Journal of molecular biology 295 (3), 627-639, 2000 | 151 | 2000 |
SPR biosensing in crude serum using ultralow fouling binary patterned peptide SAM OR Bolduc, JN Pelletier, JF Masson Analytical Chemistry 82 (9), 3699-3706, 2010 | 128 | 2010 |
Cinnamoyl inhibitors of tissue transglutaminase C Pardin, JN Pelletier, WD Lubell, JW Keillor The Journal of organic chemistry 73 (15), 5766-5775, 2008 | 128 | 2008 |
Protein fragment complementation assays for the detection of biological or drug interactions SWW Michnick, JN Pelletier, I Remy US Patent 6,270,964, 2001 | 124 | 2001 |
Comparison of in vivo selection and rational design of heterodimeric coiled coils KM Arndt, JN Pelletier, KM Müller, A Plückthun, T Alber Structure 10 (9), 1235-1248, 2002 | 117 | 2002 |
Identification and characterization of an inborn error of metabolism caused by dihydrofolate reductase deficiency S Banka, HJ Blom, J Walter, M Aziz, J Urquhart, CM Clouthier, GI Rice, ... The American Journal of Human Genetics 88 (2), 216-225, 2011 | 114 | 2011 |
Biotechnological applications of transglutaminases NM Rachel, JN Pelletier Biomolecules 3 (4), 870-888, 2013 | 111 | 2013 |
In vitro selection for catalytic activity with ribosome display P Amstutz, JN Pelletier, A Guggisberg, L Jermutus, S Cesaro-Tadic, ... Journal of the American Chemical Society 124 (32), 9396-9403, 2002 | 109 | 2002 |
Computational tools for enzyme improvement: why everyone can–and should–use them MC Ebert, JN Pelletier Current Opinion in Chemical Biology 37, 89-96, 2017 | 105 | 2017 |
Microbial transglutaminase displays broad acyl-acceptor substrate specificity MT Gundersen, JW Keillor, JN Pelletier Applied microbiology and biotechnology 98, 219-230, 2014 | 93 | 2014 |
A rapid and quantitative serum test for SARS-CoV-2 antibodies with portable surface plasmon resonance sensing A Djaileb, B Charron, MH Jodaylami, V Thibault, J Coutu, K Stevenson, ... | 78 | 2020 |
Protein fragment complementation assays for the detection of biological or drug interactions SWW Michnick, JN Pelletier, I Remy US Patent 6,428,951, 2002 | 76 | 2002 |
Peptide self-assembled monolayers for label-free and unamplified surface plasmon resonance biosensing in crude cell lysate OR Bolduc, CM Clouthier, JN Pelletier, JF Masson Analytical chemistry 81 (16), 6779-6788, 2009 | 73 | 2009 |