| Flow-cytometric isolation of human antibodies from a nonimmune Saccharomyces cerevisiae surface display library MJ Feldhaus, RW Siegel, LK Opresko, JR Coleman, JMW Feldhaus, ... Nature biotechnology 21 (2), 163-170, 2003 | 676 | 2003 |
| Prions DW Colby, SB Prusiner Cold Spring Harbor perspectives in biology 3 (1), a006833, 2011 | 631 | 2011 |
| Small-molecule aggregates inhibit amyloid polymerization BY Feng, BH Toyama, H Wille, DW Colby, SR Collins, BCH May, ... Nature chemical biology 4 (3), 197-199, 2008 | 312 | 2008 |
| Natural and synthetic prion structure from X-ray fiber diffraction H Wille, W Bian, M McDonald, A Kendall, DW Colby, L Bloch, J Ollesch, ... Proceedings of the National Academy of Sciences 106 (40), 16990-16995, 2009 | 276 | 2009 |
| Prion detection by an amyloid seeding assay DW Colby, Q Zhang, S Wang, D Groth, G Legname, D Riesner, ... Proceedings of the National Academy of Sciences 104 (52), 20914-20919, 2007 | 275 | 2007 |
| Design and construction of diverse mammalian prion strains DW Colby, K Giles, G Legname, H Wille, IV Baskakov, SJ DeArmond, ... Proceedings of the National Academy of Sciences 106 (48), 20417-20422, 2009 | 252 | 2009 |
| Inert and seed-competent tau monomers suggest structural origins of aggregation H Mirbaha, D Chen, OA Morazova, KM Ruff, AM Sharma, X Liu, ... Elife 7, e36584, 2018 | 243 | 2018 |
| Potent inhibition of huntingtin aggregation and cytotoxicity by a disulfide bond-free single-domain intracellular antibody DW Colby, YJ Chu, JP Cassady, M Duennwald, H Zazulak, JM Webster, ... Proceedings of the National Academy of Sciences 101 (51), 17616-17621, 2004 | 236 | 2004 |
| Engineering antibody affinity by yeast surface display DW Colby, BA Kellogg, CP Graff, YA Yeung, JS Swers, KD Wittrup Methods in enzymology 388, 348-358, 2004 | 208 | 2004 |
| Protease-sensitive synthetic prions DW Colby, R Wain, IV Baskakov, G Legname, CG Palmer, HOB Nguyen, ... PLoS pathogens 6 (1), e1000736, 2010 | 198 | 2010 |
| Development of a human light chain variable domain (VL) intracellular antibody specific for the amino terminus of huntingtin via yeast surface display DW Colby, P Garg, T Holden, G Chao, JM Webster, A Messer, VM Ingram, ... Journal of molecular biology 342 (3), 901-912, 2004 | 137 | 2004 |
| De novo generation of prion strains DW Colby, SB Prusiner Nature Reviews Microbiology 9 (11), 771-777, 2011 | 110 | 2011 |
| Comparative study of naturally occurring huntingtin fragments in Drosophila points to exon 1 as the most pathogenic species in Huntington's disease BA Barbaro, T Lukacsovich, N Agrawal, J Burke, DJ Bornemann, ... Human molecular genetics 24 (4), 913-925, 2015 | 105 | 2015 |
| Conformational features of tau fibrils from Alzheimer’s disease brain are faithfully propagated by unmodified recombinant protein OA Morozova, ZM March, AS Robinson, DW Colby Biochemistry 52 (40), 6960-6967, 2013 | 99 | 2013 |
| Stochastic kinetics of intracellular huntingtin aggregate formation DW Colby, JP Cassady, GC Lin, VM Ingram, KD Wittrup Nature Chemical Biology 2 (6), 319-323, 2006 | 81 | 2006 |
| The N-terminus of the prion protein is a toxic effector regulated by the C-terminus B Wu, AJ McDonald, K Markham, CB Rich, KP McHugh, J Tatzelt, ... Elife 6, e23473, 2017 | 75 | 2017 |
| Conformation-dependent epitopes recognized by prion protein antibodies probed using mutational scanning and deep sequencing KM Doolan, DW Colby Journal of molecular biology 427 (2), 328-340, 2015 | 61 | 2015 |
| Convergent replication of mouse synthetic prion strains S Ghaemmaghami, DW Colby, HOB Nguyen, S Hayashi, A Oehler, ... The American journal of pathology 182 (3), 866-874, 2013 | 41 | 2013 |
| Protein misfolding detected early in pathogenesis of transgenic mouse model of Huntington disease using amyloid seeding assay S Gupta, DW Colby Journal of Biological Chemistry 287 (13), 9982-9989, 2012 | 41 | 2012 |
| Designing well-defined photopolymerized synthetic matrices for three-dimensional culture and differentiation of induced pluripotent stem cells EM Ovadia, DW Colby, AM Kloxin Biomaterials science 6 (6), 1358-1370, 2018 | 39 | 2018 |
