Investigation of the adrenergic and opioid binding affinities, metabolic stability, plasma protein binding properties, and functional effects of selected indole-based kratom … S Obeng, SH Kamble, ME Reeves, LF Restrepo, A Patel, M Behnke, ... Journal of medicinal chemistry 63 (1), 433-439, 2019 | 113 | 2019 |
Metabolite profiling and identification of enzymes responsible for the metabolism of mitragynine, the major alkaloid of Mitragyna speciosa (kratom) SH Kamble, A Sharma, TI King, F León, CR McCurdy, BA Avery Xenobiotica, 2019 | 98 | 2019 |
Simultaneous quantification of ten key Kratom alkaloids in Mitragyna speciosa leaf extracts and commercial products by ultra‐performance liquid chromatography … A Sharma, SH Kamble, F León, NJY Chear, TI King, EC Berthold, ... Drug testing and analysis 11 (8), 1162-1171, 2019 | 83 | 2019 |
Exploration of cytochrome P450 inhibition mediated drug-drug interaction potential of kratom alkaloids SH Kamble, A Sharma, TI King, EC Berthold, F León, PKL Meyer, ... Toxicology letters 319, 148-154, 2020 | 52 | 2020 |
Metabolism of a kratom alkaloid metabolite in human plasma increases its opioid potency and efficacy SH Kamble, F León, TI King, EC Berthold, C Lopera-Londoño, ... ACS pharmacology & translational science 3 (6), 1063-1068, 2020 | 49 | 2020 |
Activity of Mitragyna speciosa (“Kratom”) Alkaloids at Serotonin Receptors F León, S Obeng, M Mottinelli, Y Chen, TI King, EC Berthold, SH Kamble, ... Journal of medicinal chemistry 64 (18), 13510-13523, 2021 | 47 | 2021 |
Pharmacokinetics of eleven kratom alkaloids following an oral dose of either traditional or commercial kratom products in rats SH Kamble, EC Berthold, TI King, SR Raju Kanumuri, R Popa, JR Herting, ... Journal of natural products 84 (4), 1104-1112, 2021 | 41 | 2021 |
Pharmacokinetics and safety of mitragynine in beagle dogs EA Maxwell, TI King, SH Kamble, KSR Raju, EC Berthold, F León, ... Planta medica 86 (17), 1278-1285, 2020 | 23 | 2020 |
The lack of contribution of 7-hydroxymitragynine to the antinociceptive effects of mitragynine in mice: a pharmacokinetic and pharmacodynamic study EC Berthold, SH Kamble, KS Raju, MA Kuntz, AS Senetra, M Mottinelli, ... Drug Metabolism and Disposition 50 (2), 158-167, 2022 | 19 | 2022 |
In vitro antioxidant and anti-glycation activity of resveratrol and its novel triester with trolox S Intagliata, A Spadaro, M Lorenti, A Panico, EA Siciliano, S Barbagallo, ... Antioxidants 10 (1), 12, 2020 | 19 | 2020 |
Adolescent nicotine and tobacco smoke exposure enhances nicotine self-administration in female rats R Chellian, A Behnood-Rod, R Wilson, SH Kamble, A Sharma, ... Neuropharmacology 176, 108243, 2020 | 17 | 2020 |
Bioanalytical method development and validation of corynantheidine, a kratom alkaloid, using UPLC-MS/MS, and its application to preclinical pharmacokinetic studies TI King, A Sharma, SH Kamble, F León, EC Berthold, R Popa, O Cerlati, ... Journal of pharmaceutical and biomedical analysis 180, 113019, 2020 | 17 | 2020 |
Preclinical pharmacokinetic study of speciociliatine, a kratom alkaloid, in rats using an UPLC-MS/MS method EC Berthold, SH Kamble, KS Raju, TI King, R Popa, A Sharma, F León, ... Journal of pharmaceutical and biomedical analysis 194, 113778, 2021 | 15 | 2021 |
Metabolism of speciociliatine, an overlooked kratom alkaloid for its potential pharmacological effects SH Kamble, EC Berthold, SRR Kanumuri, TI King, MA Kuntz, F León, ... The AAPS journal 24 (5), 86, 2022 | 14 | 2022 |
Effect of water miscible organic solvents on p-nitrophenol hydroxylase (CYP2E1) activity in rat liver microsomes PG Patil, SH Kamble, TS Shah, KR Iyer Indian Journal of Pharmaceutical Sciences 77 (3), 283, 2015 | 10 | 2015 |
Regulatory sampling of industrial hemp plant samples (Cannabis sativa L.) using UPLC-MS/MS method for detection and quantification of twelve cannabinoids EC Berthold, R Yang, A Sharma, SH Kamble, SR Kanumuri, TI King, ... Journal of Cannabis Research 2, 1-11, 2020 | 9 | 2020 |
Effect of water-miscible organic solvents on CYP450-mediated metoprolol and imipramine metabolism in rat liver microsomes TS Shah, SH Kamble, PG Patil, KR Iyer Indian Journal of Pharmaceutical Sciences 77 (4), 382, 2015 | 9 | 2015 |
Comparative pharmacokinetics of commercially available cannabidiol isolate, broad-spectrum, and full-spectrum products EC Berthold, SH Kamble, SRR Kanumuri, MA Kuntz, AS Senetra, ... European Journal of Drug Metabolism and Pharmacokinetics 48 (4), 427-435, 2023 | 8 | 2023 |
Bioanalytical method development and pharmacokinetics of MCI-92, a sigma-1 receptor ligand R Popa, SH Kamble, RS Kanumuri, TI King, EC Berthold, S Intagliata, ... Journal of Pharmaceutical and Biomedical Analysis 191, 113610, 2020 | 6 | 2020 |
Exploring 1-adamantanamine as an alternative amine moiety for metabolically labile azepane ring in newly synthesized benzo[d]thiazol-2(3H)one σ receptor ligands S Intagliata, H Agha, TA Kopajtic, JL Katz, SH Kamble, A Sharma, ... Medicinal Chemistry Research 29, 1697-1706, 2020 | 6 | 2020 |