Oxygen Activation and Radical Transformations in Heme Proteins and Metalloporphyrins X Huang, JT Groves Chemical Reviews 118 (5), 2491-2553, 2018 | 782 | 2018 |
Oxidative aliphatic C–H fluorination with fluoride ion catalyzed by a manganese porphyrin W Liu, X Huang, MJ Cheng, RJ Nielsen, WA Goddard, JT Groves Science 337 (6100), 1322-1325, 2012 | 535 | 2012 |
Manganese-Catalyzed Late-Stage Aliphatic C–H Azidation X Huang, TM Bergsten, JT Groves Journal of the American Chemical Society 137 (16), 5300-5303, 2015 | 304 | 2015 |
Beyond ferryl-mediated hydroxylation: 40 years of the rebound mechanism and C–H activation X Huang, JT Groves Journal of Biological Inorganic Chemistry 22 (2-3), 185-207, 2017 | 288 | 2017 |
Genetically programmed chiral organoborane synthesis SBJ Kan, X Huang, Y Gumulya, K Chen, FH Arnold Nature 552, 132–136, 2017 | 282 | 2017 |
Enzymatic assembly of carbon–carbon bonds via iron-catalysed sp3 C–H functionalization RK Zhang, K Chen, X Huang, L Wohlschlager, H Renata, FH Arnold Nature 565, 67–72, 2019 | 279 | 2019 |
Late Stage Benzylic C–H Fluorination with [18F] Fluoride for PET Imaging X Huang, W Liu, H Ren, R Neelamegam, JM Hooker, JT Groves Journal of the American Chemical Society 136 (19), 6842-6845, 2014 | 262 | 2014 |
Enzymatic construction of highly strained carbocycles K Chen, X Huang, SBJ Kan, RK Zhang, FH Arnold Science 360 (6384), 71-75, 2018 | 221 | 2018 |
Taming Azide Radicals for Catalytic C–H Azidation X Huang, JT Groves ACS catalysis 6, 751-759, 2016 | 156 | 2016 |
Targeted fluorination with the fluoride ion by manganese‐catalyzed decarboxylation X Huang, W Liu, JM Hooker, JT Groves Angewandte Chemie International Edition 127 (17), 5330-5334, 2015 | 149 | 2015 |
Selective C–H bond functionalization with engineered heme proteins: new tools to generate complexity RK Zhang, X Huang, FH Arnold Current Opinion in Chemical Biology 49, 67-75, 2019 | 121 | 2019 |
Enantiodivergent α-Amino C–H Fluoroalkylation Catalyzed by Engineered Cytochrome P450s J Zhang, X Huang, RK Zhang, FH Arnold Journal of the American Chemical Society, 2019 | 113 | 2019 |
A biocatalytic platform for synthesis of chiral α-trifluoromethylated organoborons X Huang, M Garcia-Borràs, K Miao, SBJ Kan, A Zutshi, KN Houk, ... ACS Central Science 5 (2), 270-276, 2019 | 92 | 2019 |
Site-selective (18)F fluorination of unactivated C–H bonds mediated by a manganese porphyrin W Liu, X Huang, MS Placzek, SW Krska, P McQuade, JM Hooker, ... Chemical Science 9, 1168-1172, 2018 | 83 | 2018 |
The Enigmatic P450 Decarboxylase OleT is Capable of, but Evolved to Frustrate, Oxygen Rebound Chemistry TMM Chun H Hsieh, Xiongyi Huang, Jose A Amaya, Cooper D Rutland, Carson L ... Biochemistry 56 (26), 3347-3357, 2017 | 67 | 2017 |
Alkyl Isocyanates via Manganese-Catalyzed C-H Activation for the Preparation of Substituted Ureas X Huang, T Zhuang, PA Kates, H Gao, X Chen, JT Groves Journal of the American Chemical Society 139 (43), 15407-15413, 2017 | 66 | 2017 |
Oxidative aliphatic CH fluorination with manganese catalysts and fluoride ion W Liu, X Huang, JT Groves Nature protocols 8 (12), 2348, 2013 | 60 | 2013 |
Parallel and competitive pathways for substrate desaturation, hydroxylation, and radical rearrangement by the non-heme diiron hydroxylase AlkB HLR Cooper, G Mishra, X Huang, M Pender-Cudlip, RN Austin, ... Journal of the American Chemical Society 134 (50), 20365-20375, 2012 | 55 | 2012 |
Directed evolution of nonheme iron enzymes to access abiological radical-relay C(sp3)-H azidation J Rui, Q Zhao, AJ Huls, J Soler, JC Paris, Z Chen, V Reshetnikov, Y Yang, ... Science 376, 869-874, 2022 | 48 | 2022 |
A theoretical study on C−COOH homolytic bond dissociation enthalpies J Shi, XY Huang, JP Wang, R Li Journal of Physical Chemistry A 114 (21), 6263-6272, 2010 | 48 | 2010 |