Signaling mechanisms of glucose-induced F-actin remodeling in pancreatic islet β cells MA Kalwat, DC Thurmond Experimental & molecular medicine 45 (8), e37-e37, 2013 | 165 | 2013 |
Mechanisms of the amplifying pathway of insulin secretion in the β cell MA Kalwat, MH Cobb Pharmacology & therapeutics 179, 17-30, 2017 | 157 | 2017 |
Munc18c phosphorylation by the insulin receptor links cell signaling directly to SNARE exocytosis JL Jewell, E Oh, L Ramalingam, MA Kalwat, VS Tagliabracci, L Tackett, ... Journal of Cell Biology 193 (1), 185-199, 2011 | 95 | 2011 |
Munc18-1 regulates first-phase insulin release by promoting granule docking to multiple syntaxin isoforms E Oh, MA Kalwat, MJ Kim, M Verhage, DC Thurmond Journal of Biological Chemistry 287 (31), 25821-25833, 2012 | 91 | 2012 |
A p21-activated kinase (PAK1) signaling cascade coordinately regulates F-actin remodeling and insulin granule exocytosis in pancreatic β cells MA Kalwat, SM Yoder, Z Wang, DC Thurmond Biochemical pharmacology 85 (6), 808-816, 2013 | 79 | 2013 |
Stimulus-induced S-nitrosylation of Syntaxin 4 impacts insulin granule exocytosis DA Wiseman, MA Kalwat, DC Thurmond Journal of Biological Chemistry 286 (18), 16344-16354, 2011 | 58 | 2011 |
Gelsolin associates with the N terminus of syntaxin 4 to regulate insulin granule exocytosis MA Kalwat, DA Wiseman, W Luo, Z Wang, DC Thurmond Molecular endocrinology 26 (1), 128-141, 2012 | 55 | 2012 |
Cool-1/βPIX functions as a guanine nucleotide exchange factor in the cycling of Cdc42 to regulate insulin secretion EM Kepner, SM Yoder, E Oh, MA Kalwat, Z Wang, LA Quilliam, ... American Journal of Physiology-Endocrinology and Metabolism 301 (6), E1072-E1080, 2011 | 52 | 2011 |
Doc2b is a key effector of insulin secretion and skeletal muscle insulin sensitivity L Ramalingam, E Oh, SM Yoder, JT Brozinick, MA Kalwat, AJ Groffen, ... Diabetes 61 (10), 2424-2432, 2012 | 51 | 2012 |
Pancreatitis is an FGF21-deficient state that is corrected by replacement therapy G Hernandez, T Luo, TA Javed, L Wen, MA Kalwat, K Vale, F Ammouri, ... Science translational medicine 12 (525), eaay5186, 2020 | 49 | 2020 |
Insulin Promoter-Driven Gaussia Luciferase-Based Insulin Secretion Biosensor Assay for Discovery of β-Cell Glucose-Sensing Pathways MA Kalwat, C Wichaidit, AY Nava Garcia, MK McCoy, K McGlynn, ... ACS sensors 1 (10), 1208-1212, 2016 | 43 | 2016 |
Isoxazole alters metabolites and gene expression, decreasing proliferation and promoting a neuroendocrine phenotype in β-cells MA Kalwat, Z Huang, C Wichaidit, K McGlynn, S Earnest, C Savoia, ... ACS chemical biology 11 (4), 1128-1136, 2016 | 36 | 2016 |
The pancreatic ß-cell response to secretory demands and adaption to stress MA Kalwat, D Scheuner, K Rodrigues-dos-Santos, DL Eizirik, MH Cobb Endocrinology 162 (11), bqab173, 2021 | 17 | 2021 |
Sucralose activates an ERK1/2–ribosomal protein S6 signaling axis ML Guerra, MA Kalwat, K McGlynn, MH Cobb FEBS Open Bio 7 (2), 174-186, 2017 | 13 | 2017 |
High-throughput screening for insulin secretion modulators MA Kalwat Exocytosis and endocytosis: methods and protocols, 131-138, 2021 | 8 | 2021 |
Chromomycin A2 potently inhibits glucose-stimulated insulin secretion from pancreatic β cells MA Kalwat, IH Hwang, J Macho, MG Grzemska, JZ Yang, K McGlynn, ... Journal of General Physiology 150 (12), 1747-1757, 2018 | 8 | 2018 |
α2-Adrenergic Disruption of β Cell BDNF-TrkB Receptor Tyrosine Kinase Signaling MA Kalwat, Z Huang, DD Binns, K McGlynn, MH Cobb Frontiers in Cell and Developmental Biology 8, 576396, 2020 | 4 | 2020 |
Measuring relative insulin secretion using a co-secreted luciferase surrogate M Kalwat, MH Cobb JoVE (Journal of Visualized Experiments), e59926, 2019 | 4 | 2019 |
BDNF/TrkB signaling in pancreatic islet beta cells M Kalwat, Z Huang, K McGlynn, MH Cobb Seminars in fetal & neonatal medicine, 2018 | 3 | 2018 |
Small molecule-mediated insulin hypersecretion induces transient ER stress response and loss of beta cell function K Rodrigues-dos-Santos, G Roy, DD Binns, MG Grzemska, LF Barella, ... Endocrinology 163 (7), bqac081, 2022 | 2 | 2022 |