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Targeting the hedgehog transcription factors GLI1 and GLI2 restores sensitivity to vemurafenib-resistant human melanoma cells F Faiao-Flores, DK Alves-Fernandes, PC Pennacchi, S Sandri, ... Oncogene 36 (13), 1849-1861, 2017 | 91 | 2017 |
Leveraging transcriptional dynamics to improve BRAF inhibitor responses in melanoma I Smalley, E Kim, J Li, P Spence, CJ Wyatt, Z Eroglu, VK Sondak, ... EBioMedicine 48, 178-190, 2019 | 85 | 2019 |
HDAC inhibition enhances the in vivo efficacy of MEK inhibitor therapy in uveal melanoma F Faião-Flores, MF Emmons, MA Durante, F Kinose, B Saha, B Fang, ... Clinical Cancer Research 25 (18), 5686-5701, 2019 | 82 | 2019 |
Glycated reconstructed human skin as a platform to study the pathogenesis of skin aging PC Pennacchi, MES de Almeida, OLA Gomes, F Faião-Flores, ... Tissue Engineering Part A 21 (17-18), 2417-2425, 2015 | 80 | 2015 |
Sensitive simultaneous detection of seven sexually transmitted agents in semen by multiplex-PCR and of HPV by single PCR F Gimenes, FS Medina, ALP Abreu, MMT Irie, IB Esquicati, N Malagutti, ... PloS one 9 (6), e98862, 2014 | 79 | 2014 |
A new reconstructed human epidermis for in vitro skin irritation testing T do Nascimento Pedrosa, CM Catarino, PC Pennacchi, SR de Assis, ... Toxicology in Vitro 42, 31-37, 2017 | 77 | 2017 |
Inhibition of autophagy enhances the effects of the AKT inhibitor MK‐2206 when combined with paclitaxel and carboplatin in BRAF wild‐type melanoma VW Rebecca, RR Massaro, IV Fedorenko, VK Sondak, ARA Anderson, ... Pigment cell & melanoma research 27 (3), 465-478, 2014 | 75 | 2014 |
The oxidation of p-phenylenediamine, an ingredient used for permanent hair dyeing purposes, leads to the formation of hydroxyl radicals: Oxidative stress and DNA damage in … TB Zanoni, F Hudari, A Munnia, M Peluso, RW Godschalk, MVB Zanoni, ... Toxicology letters 239 (3), 194-204, 2015 | 66 | 2015 |
HPV16 oncoproteins induce MMPs/RECK-TIMP-2 imbalance in primary keratinocytes: possible implications in cervical carcinogenesis LBS Cardeal, E Boccardo, L Termini, T Rabachini, MA Andreoli, ... PLoS One 7 (3), e33585, 2012 | 62 | 2012 |
Higher expression and activity of metalloproteinases in human cervical carcinoma cell lines is associated with HPV presence LBS Cardeal, CA Brohem, TCS Corrêa, SMB Winnischofer, F Nakano, ... Biochemistry and cell biology 84 (5), 713-719, 2006 | 62 | 2006 |
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Co-localization of nestin and insulin and expression of islet cell markers in long-term human pancreatic nestin-positive cell cultures SS Maria-Engler, MLC Corrêa-Giannella, L Labriola, K Krogh, C Colin, ... Journal of endocrinology 183 (3), 455-467, 2004 | 60 | 2004 |
Co-encapsulation of paclitaxel and C6 ceramide in tributyrin-containing nanocarriers improve co-localization in the skin and potentiate cytotoxic effects in 2D and 3D models VFM Carvalho, A Migotto, DV Giacone, DP de Lemos, TB Zanoni, ... European Journal of Pharmaceutical Sciences 109, 131-143, 2017 | 59 | 2017 |