The clinical potential of gene editing as a tool to engineer cell-based therapeutics C Ashmore-Harris, GO Fruhwirth Clinical and Translational Medicine 9 (1), 15, 2020 | 70 | 2020 |
Non-invasive reporter gene imaging of cell therapies, including T cells and stem cells C Ashmore-Harris, M Iafrate, A Saleem, GO Fruhwirth Molecular Therapy 28 (6), 1392-1416, 2020 | 66 | 2020 |
Spatiotemporal PET imaging reveals differences in CAR-T tumor retention in triple-negative breast cancer models A Volpe, C Lang, L Lim, F Man, E Kurtys, C Ashmore-Harris, P Johnson, ... Molecular Therapy 28 (10), 2271-2285, 2020 | 63 | 2020 |
Human biliary epithelial cells from discarded donor livers rescue bile duct structure and function in a mouse model of biliary disease JM Hallett, S Ferreira-Gonzalez, TY Man, AM Kilpatrick, H Esser, ... Cell stem cell 29 (3), 355-371. e10, 2022 | 36 | 2022 |
Reporter gene-engineering of human induced pluripotent stem cells during differentiation renders in vivo traceable hepatocyte-like cells accessible C Ashmore-Harris, SJI Blackford, B Grimsdell, E Kurtys, MC Glatz, ... Stem Cell Research 41, 101599, 2019 | 17 | 2019 |
Acquired resistance to oxaliplatin is not directly associated with increased resistance to DNA damage in SK-N-ASrOXALI4000, a newly established oxaliplatin … E Saintas, L Abrahams, GT Ahmad, AOM Ajakaiye, AS AlHumaidi, ... PLoS One 12 (2), e0172140, 2017 | 13 | 2017 |
Generation of In vivo traceable hepatocyte-like cells from human iPSCs C Ashmore-Harris, GO Fruhwirth Hepatocytes: Methods and Protocols, 15-49, 2022 | 3 | 2022 |
Utilising an in silico model to predict outcomes in senescence-driven acute liver injury C Ashmore-Harris, E Antonopoulou, RE Aird, TY Man, SM Finney, ... npj Regenerative Medicine 9 (1), 26, 2024 | 2 | 2024 |
Exploiting in silico modelling to enhance translation of liver cell therapies from bench to bedside C Ashmore-Harris, E Antonopoulou, SM Finney, MR Vieira, MG Hennessy, ... npj Regenerative Medicine 9 (1), 19, 2024 | 1 | 2024 |
Gene editing enables non-invasive in vivo PET imaging of human induced pluripotent stem cell derived liver bud organoids C Ashmore-Harris, H Ayabe, E Yoshizawa, T Arisawa, Y Takada, ... Molecular Therapy Methods & Clinical Development, 2025 | | 2025 |
Host hepatocyte senescence determines the success of hepatocyte transplantation in a mouse model of liver injury VL Gadd, S Ferreira-Gonzalez, TY Man, AM Kilpatrick, RE Aird, IP Smith, ... Journal of Hepatology, 2025 | | 2025 |
Biliary senescence drives hepatocyte VCAM-1 expression and liver neutrophil infiltration M Ferreira, A Kilpatrick, DR Torres, S Ferreira-Gonzalez, V Gadd, J Man, ... AASLD (American Association for the Study of Liver Diseases) The Liver Meeting®, 2024 | | 2024 |
Exploiting in silico modelling to enhance translation of liver cell therapies from bench to bedside MG Hennessy, S Waters, C Ashmore-Harris, E Antonopoulou, S Finney, ... npj Regenerative Medicine 9, 2024 | | 2024 |
Biliary senescence affects the transcriptomic landscape of murine hepatocytes M Ferreira, A Kilpatrick, DR Torres, S Ferreira-Gonzalez, J Man, R Aird, ... EASL (European Association for the Study of the Liver) monothematic …, 2023 | | 2023 |
Labelling primary murine hepatocytes with a near-infrared dye facilitates repeat non-invasive in vivo tracking of engraftment and survival in an acute model of liver injury. C Ashmore-Harris, V Gadd, J Man, R Aird, M Macmillan, DR Torres, ... World Molecular Imaging Congress, 2023 | | 2023 |
Primary cilia in biliary regeneration-a potential approach to improve outcomes in liver transplantation H Esser, S Ferreira-Gonzalez, TY Man, A Kilpatrick, DR Torres, RE Aird, ... Journal of Hepatology 77, S85, 2022 | | 2022 |
Integration of imaging to enable iPSC-derived hepatocyte tracking in vivo C Ashmore-Harris King's College London, 2020 | | 2020 |