A microbial supply chain for production of the anti-cancer drug vinblastine J Zhang, LG Hansen, O Gudich, K Viehrig, LMM Lassen, L Schrübbers, ... Nature 609 (7926), 341-347, 2022 | 247 | 2022 |
Engineering prokaryotic transcriptional activators as metabolite biosensors in yeast ML Skjoedt, T Snoek, KR Kildegaard, D Arsovska, M Eichenberger, ... Nature chemical biology 12 (11), 951-958, 2016 | 228 | 2016 |
Development of biosensors and their application in metabolic engineering J Zhang, MK Jensen, JD Keasling Current opinion in chemical biology 28, 1-8, 2015 | 212 | 2015 |
Combining mechanistic and machine learning models for predictive engineering and optimization of tryptophan metabolism J Zhang, SD Petersen, T Radivojevic, A Ramirez, A Pérez-Manríquez, ... Nature communications 11 (1), 4880, 2020 | 210 | 2020 |
CasEMBLR: Cas9-Facilitated Multiloci Genomic Integration of in Vivo Assembled DNA Parts in Saccharomyces cerevisiae T Jakociunas, AS Rajkumar, J Zhang, D Arsovska, A Rodriguez, ... ACS synthetic biology 4 (11), 1226-1234, 2015 | 183 | 2015 |
Antibiotic overproduction in Streptomyces coelicolor A3 (2) mediated by phosphofructokinase deletion I Borodina, J Siebring, J Zhang, CP Smith, G van Keulen, L Dijkhuizen, ... Journal of Biological Chemistry 283 (37), 25186-25199, 2008 | 167 | 2008 |
Transcriptional reprogramming in yeast using dCas9 and combinatorial gRNA strategies ED Jensen, R Ferreira, T Jakočiūnas, D Arsovska, J Zhang, L Ding, ... Microbial cell factories 16, 1-16, 2017 | 133 | 2017 |
Integrated multilaboratory systems biology reveals differences in protein metabolism between two reference yeast strains AB Canelas, N Harrison, A Fazio, J Zhang, JP Pitkänen, J Van Den Brink, ... Nature communications 1 (1), 145, 2010 | 133 | 2010 |
Optimization of< sup> 13</sup> C isotopic tracers for metabolic flux analysis in mammalian cells JL Walther, CM Metallo, J Zhang, G Stephanopoulos Metabolic Engineering, 2011 | 95 | 2011 |
Mapping the interaction of Snf1 with TORC1 in Saccharomyces cerevisiae J Zhang, S Vaga, P Chumnanpuen, R Kumar, GN Vemuri, R Aebersold, ... Molecular systems biology 7 (1), 545, 2011 | 86 | 2011 |
Engineering an NADPH/NADP+ Redox Biosensor in Yeast J Zhang, N Sonnenschein, TPB Pihl, KR Pedersen, MK Jensen, ... ACS Synthetic Biology 5 (12), 1546-1556, 2016 | 83 | 2016 |
An orthogonal and pH-tunable sensor-selector for muconic acid biosynthesis in yeast T Snoek, D Romero-Suarez, J Zhang, F Ambri, ML Skjoedt, S Sudarsan, ... ACS synthetic biology 7 (4), 995-1003, 2018 | 66 | 2018 |
13C isotope-assisted methods for quantifying glutamine metabolism in cancer cells J Zhang, WS Ahn, PA Gameiro, MA Keibler, Z Zhang, G Stephanopoulos Methods in enzymology 542, 369-389, 2014 | 62 | 2014 |
Heterologous production of non-ribosomal peptide LLD-ACV in Saccharomyces cerevisiae V Siewers, X Chen, L Huang, J Zhang, J Nielsen Metabolic Engineering 11 (6), 391-397, 2009 | 47 | 2009 |
The β‐subunits of the Snf1 kinase in Saccharomyces cerevisiae, Gal83 and Sip2, but not Sip1, are redundant in glucose derepression and regulation of sterol … J Zhang, L Olsson, J Nielsen Molecular microbiology 77 (2), 371-383, 2010 | 42 | 2010 |
Systems biology of energy homeostasis in yeast J Zhang, G Vemuri, J Nielsen Current opinion in microbiology 13 (3), 382-388, 2010 | 37 | 2010 |
Modular 5′-UTR hexamers for context-independent tuning of protein expression in eukaryotes SD Petersen, J Zhang, JS Lee, T Jakočiūnas, LM Grav, HF Kildegaard, ... Nucleic acids research 46 (21), e127-e127, 2018 | 27 | 2018 |
Metabolic engineering: enabling technology of a bio-based economy J Zhang, A Babtie, G Stephanopoulos Current Opinion in Chemical Engineering 1 (4), 355-362, 2012 | 23 | 2012 |
Integrated analysis of transcriptome and lipid profiling reveals the co-influences of inositol–choline and Snf1 in controlling lipid biosynthesis in yeast P Chumnanpuen, J Zhang, I Nookaew, J Nielsen Molecular Genetics and Genomics, 1-14, 2012 | 23 | 2012 |
Deploying microbial synthesis for halogenating and diversifying medicinal alkaloid scaffolds SA Bradley, J Zhang, MK Jensen Frontiers in Bioengineering and Biotechnology 8, 594126, 2020 | 17 | 2020 |