Adeno-associated virus serotype 9 transduction in the central nervous system of nonhuman primates L Samaranch, EA Salegio, W San Sebastian, AP Kells, KD Foust, ... Human gene therapy 23 (4), 382-389, 2012 | 341 | 2012 |
PINK1-linked parkinsonism is associated with Lewy body pathology L Samaranch, O Lorenzo-Betancor, JM Arbelo, I Ferrer, E Lorenzo, ... Brain 133 (4), 1128-1142, 2010 | 299 | 2010 |
Genetic screening of Alzheimer's disease genes in Iberian and African samples yields novel mutations in presenilins and APP RJ Guerreiro, M Baquero, R Blesa, M Boada, JM Brás, MJ Bullido, ... Neurobiology of aging 31 (5), 725-731, 2010 | 253 | 2010 |
Accelerated amyloid deposition, neurofibrillary degeneration and neuronal loss in double mutant APP/tau transgenic mice EM Ribé, M Pérez, B Puig, I Gich, F Lim, M Cuadrado, T Sesma, S Catena, ... Neurobiology of disease 20 (3), 814-822, 2005 | 220 | 2005 |
Axonal transport of adeno-associated viral vectors is serotype-dependent EA Salegio, L Samaranch, AP Kells, G Mittermeyer, W San Sebastian, ... Gene therapy 20 (3), 348-352, 2013 | 193 | 2013 |
Strong cortical and spinal cord transduction after AAV7 and AAV9 delivery into the cerebrospinal fluid of nonhuman primates L Samaranch, EA Salegio, W San Sebastian, AP Kells, JR Bringas, ... Human gene therapy 24 (5), 526-532, 2013 | 172 | 2013 |
AAV9-mediated expression of a non-self protein in nonhuman primate central nervous system triggers widespread neuroinflammation driven by antigen-presenting cell transduction L Samaranch, W San Sebastian, AP Kells, EA Salegio, G Heller, ... Molecular Therapy 22 (2), 329-337, 2014 | 162 | 2014 |
Homocysteine and cognitive impairment in Parkinson's disease: a biochemical, neuroimaging, and genetic study MC Rodriguez‐Oroz, PM Lage, J Sanchez‐Mut, I Lamet, ... Movement disorders: official journal of the Movement Disorder Society 24 (10 …, 2009 | 117 | 2009 |
Translational Fidelity of Intrathecal Delivery of Self-Complementary AAV9–Survival Motor Neuron 1 for Spinal Muscular Atrophy MA Passini, J Bu, AM Richards, CM Treleaven, JA Sullivan, CR O'Riordan, ... Human gene therapy 25 (7), 619-630, 2014 | 113 | 2014 |
MR-guided parenchymal delivery of adeno-associated viral vector serotype 5 in non-human primate brain L Samaranch, B Blits, W San Sebastian, P Hadaczek, J Bringas, ... Gene therapy 24 (4), 253-261, 2017 | 104 | 2017 |
Replication of MAPT and SNCA, but not PARK16‐18, as susceptibility genes for Parkinson's disease IF Mata, D Yearout, V Alvarez, E Coto, L de Mena, R Ribacoba, ... Movement disorders 26 (5), 819-823, 2011 | 90 | 2011 |
Memory decline evolves independently of disease activity in MS B Duque, J Sepulcre, B Bejarano, L Samaranch, P Pastor, P Villoslada Multiple Sclerosis Journal 14 (7), 947-953, 2008 | 86 | 2008 |
Analysis of the Micro‐RNA‐133 and PITX3 genes in Parkinson's disease L De Mena, E Coto, LF Cardo, M Díaz, M Blázquez, R Ribacoba, ... American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 153 …, 2010 | 83 | 2010 |
Widespread optogenetic expression in macaque cortex obtained with MR-guided, convection enhanced delivery (CED) of AAV vector to the thalamus A Yazdan-Shahmorad, N Tian, V Kharazia, L Samaranch, A Kells, ... Journal of neuroscience methods 293, 347-358, 2018 | 71 | 2018 |
Adeno-associated virus type 6 is retrogradely transported in the non-human primate brain W San Sebastian, L Samaranch, G Heller, AP Kells, J Bringas, P Pivirotto, ... Gene therapy 20 (12), 1178-1183, 2013 | 69 | 2013 |
Axonal transport of AAV9 in nonhuman primate brain F Green, L Samaranch, HS Zhang, A Manning-Bog, K Meyer, J Forsayeth, ... Gene therapy 23 (6), 520-526, 2016 | 64 | 2016 |
Extensive transduction and enhanced spread of a modified AAV2 capsid in the non-human primate CNS J Naidoo, LM Stanek, K Ohno, S Trewman, L Samaranch, P Hadaczek, ... Molecular Therapy 26 (10), 2418-2430, 2018 | 62 | 2018 |
AAV viral vector delivery to the brain by shape-conforming MR-guided infusions KS Bankiewicz, V Sudhakar, L Samaranch, W San Sebastian, J Bringas, ... Journal of Controlled Release 240, 434-442, 2016 | 62 | 2016 |
A Search for SNCA 3′ UTR Variants Identified SNP rs356165 as a Determinant of Disease Risk and Onset Age in Parkinson’s Disease LF Cardo, E Coto, L De Mena, R Ribacoba, O Lorenzo-Betancor, P Pastor, ... Journal of Molecular Neuroscience 47, 425-430, 2012 | 61 | 2012 |
Genetic variation in APOE cluster region and Alzheimer's disease risk S Cervantes, L Samaranch, JM Vidal-Taboada, I Lamet, MJ Bullido, ... Neurobiology of aging 32 (11), 2107. e7-2107. e17, 2011 | 58 | 2011 |