Epidemiologic features and clinical course of patients infected with SARS-CoV-2 in Singapore BE Young, SWX Ong, S Kalimuddin, JG Low, SY Tan, J Loh, OT Ng, ... Jama 323 (15), 1488-1494, 2020 | 2554 | 2020 |
Autoantibodies against type I IFNs in patients with life-threatening COVID-19 P Bastard, LB Rosen, Q Zhang, E Michailidis, HH Hoffmann, Y Zhang, ... Science 370 (6515), eabd4585, 2020 | 2527 | 2020 |
Inborn errors of type I IFN immunity in patients with life-threatening COVID-19 Q Zhang, P Bastard, Z Liu, J Le Pen, M Moncada-Velez, J Chen, M Ogishi, ... Science 370 (6515), eabd4570, 2020 | 2186 | 2020 |
Baricitinib plus remdesivir for hospitalized adults with Covid-19 AC Kalil, TF Patterson, AK Mehta, KM Tomashek, CR Wolfe, V Ghazaryan, ... New England Journal of Medicine 384 (9), 795-807, 2021 | 1806 | 2021 |
A SARS-CoV-2 surrogate virus neutralization test based on antibody-mediated blockage of ACE2–spike protein–protein interaction CW Tan, WN Chia, X Qin, P Liu, MIC Chen, C Tiu, Z Hu, VCW Chen, ... Nature biotechnology 38 (9), 1073-1078, 2020 | 1179 | 2020 |
Detection of air and surface contamination by SARS-CoV-2 in hospital rooms of infected patients PY Chia, KK Coleman, YK Tan, SWX Ong, M Gum, SK Lau, XF Lim, ... Nature communications 11 (1), 2800, 2020 | 935 | 2020 |
Investigation of three clusters of COVID-19 in Singapore: implications for surveillance and response measures R Pung, CJ Chiew, BE Young, S Chin, MIC Chen, HE Clapham, AR Cook, ... The Lancet 395 (10229), 1039-1046, 2020 | 796 | 2020 |
Early induction of functional SARS-CoV-2-specific T cells associates with rapid viral clearance and mild disease in COVID-19 patients AT Tan, M Linster, CW Tan, N Le Bert, WN Chia, K Kunasegaran, ... Cell reports 34 (6), 2021 | 662 | 2021 |
Effect of piperacillin-tazobactam vs meropenem on 30-day mortality for patients with E coli or Klebsiella pneumoniae bloodstream infection and ceftriaxone resistance: a … PNA Harris, PA Tambyah, DC Lye, Y Mo, TH Lee, M Yilmaz, TH Alenazi, ... Jama 320 (10), 984-994, 2018 | 640 | 2018 |
Assessing viral shedding and infectivity of tears in coronavirus disease 2019 (COVID-19) patients IYJ Seah, DE Anderson, AEZ Kang, L Wang, P Rao, BE Young, DC Lye, ... Ophthalmology 127 (7), 977-979, 2020 | 537 | 2020 |
Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, J Manry, ... Science immunology 6 (62), eabl4340, 2021 | 466 | 2021 |
Effects of a major deletion in the SARS-CoV-2 genome on the severity of infection and the inflammatory response: an observational cohort study BE Young, SW Fong, YH Chan, TM Mak, LW Ang, DE Anderson, CYP Lee, ... The lancet 396 (10251), 603-611, 2020 | 465 | 2020 |
Two linear epitopes on the SARS-CoV-2 spike protein that elicit neutralising antibodies in COVID-19 patients CM Poh, G Carissimo, B Wang, SN Amrun, CYP Lee, RSL Chee, ... Nature communications 11 (1), 2806, 2020 | 423* | 2020 |
Virological and serological kinetics of SARS-CoV-2 Delta variant vaccine breakthrough infections: a multicentre cohort study PY Chia, SWX Ong, CJ Chiew, LW Ang, JM Chavatte, TM Mak, L Cui, ... Clinical microbiology and infection 28 (4), 612. e1-612. e7, 2022 | 396 | 2022 |
Dynamics of SARS-CoV-2 neutralising antibody responses and duration of immunity: a longitudinal study WN Chia, F Zhu, SWX Ong, BE Young, SW Fong, N Le Bert, CW Tan, ... The Lancet Microbe 2 (6), e240-e249, 2021 | 374 | 2021 |
Clinical and virological features of SARS-CoV-2 variants of concern: a retrospective cohort study comparing B. 1.1. 7 (Alpha), B. 1.315 (Beta), and B. 1.617. 2 (Delta) SWX Ong, CJ Chiew, LW Ang, TM Mak, L Cui, MPHS Toh, YD Lim, ... | 360 | 2021 |
Risk factors for severe disease and efficacy of treatment in patients infected with COVID-19: a systematic review, meta-analysis, and meta-regression analysis JJY Zhang, KS Lee, LW Ang, YS Leo, BE Young Clinical Infectious Diseases 71 (16), 2199-2206, 2020 | 351 | 2020 |
X-linked recessive TLR7 deficiency in~ 1% of men under 60 years old with life-threatening COVID-19 T Asano, B Boisson, F Onodi, D Matuozzo, M Moncada-Velez, ... Science immunology 6 (62), eabl4348, 2021 | 344 | 2021 |
A neutralizing monoclonal antibody for hospitalized patients with Covid-19 Activ-3/Tico Ly-CoV555 Study Group New England Journal of Medicine 384 (10), 905-914, 2021 | 336 | 2021 |
Discovery and genomic characterization of a 382-nucleotide deletion in ORF7b and ORF8 during the early evolution of SARS-CoV-2 YCF Su, DE Anderson, BE Young, M Linster, F Zhu, J Jayakumar, ... MBio 11 (4), 10.1128/mbio. 01610-20, 2020 | 287* | 2020 |