The impact of natural products upon modern drug discovery A Ganesan Current opinion in chemical biology 12 (3), 306-317, 2008 | 774 | 2008 |
Natural products and combinatorial chemistry: back to the future JY Ortholand, A Ganesan Current opinion in chemical biology 8 (3), 271-280, 2004 | 499 | 2004 |
Thirty years of HDAC inhibitors: 2020 insight and hindsight TCS Ho, AHY Chan, A Ganesan Journal of medicinal chemistry 63 (21), 12460-12484, 2020 | 457 | 2020 |
Identification of a chemical probe for NAADP by virtual screening E Naylor, A Arredouani, SR Vasudevan, AM Lewis, R Parkesh, A Mizote, ... Nature chemical biology 5 (4), 220-226, 2009 | 345 | 2009 |
The timeline of epigenetic drug discovery: from reality to dreams A Ganesan, PB Arimondo, MG Rots, C Jeronimo, M Berdasco Clinical epigenetics 11, 1-17, 2019 | 298 | 2019 |
TPC2 is a novel NAADP-sensitive Ca2+ release channel, operating as a dual sensor of luminal pH and Ca2+ SJ Pitt, TM Funnell, M Sitsapesan, E Venturi, K Rietdorf, M Ruas, ... Journal of Biological Chemistry 285 (45), 35039-35046, 2010 | 249 | 2010 |
The N-Acyliminium Pictet−Spengler Condensation as a Multicomponent Combinatorial Reaction on Solid Phase and Its Application to the Synthesis of … H Wang, A Ganesan Organic Letters 1 (10), 1647-1649, 1999 | 167 | 1999 |
Total synthesis of spiruchostatin A, a potent histone deacetylase inhibitor A Yurek-George, F Habens, M Brimmell, G Packham, A Ganesan Journal of the American Chemical Society 126 (4), 1030-1031, 2004 | 144 | 2004 |
Epigenetic polypharmacology: from combination therapy to multitargeted drugs AR de Lera, A Ganesan Clinical epigenetics 8, 1-21, 2016 | 141 | 2016 |
A biomimetic total synthesis of (−)-spirotryprostatin B and related studies H Wang, A Ganesan The Journal of organic chemistry 65 (15), 4685-4693, 2000 | 140 | 2000 |
Strategies for the dynamic integration of combinatorial synthesis and screening A Ganesan Angewandte Chemie International Edition 37 (20), 2828-2831, 1998 | 140* | 1998 |
Enantioselective synthesis of tranylcypromine analogues as lysine demethylase (LSD1) inhibitors H Benelkebir, C Hodgkinson, PJ Duriez, AL Hayden, RA Bulleid, ... Bioorganic & medicinal chemistry 19 (12), 3709-3716, 2011 | 139 | 2011 |
Natural products as a hunting ground for combinatorial chemistry A Ganesan Current opinion in biotechnology 15 (6), 584-590, 2004 | 137 | 2004 |
Oral administration of peptide‐based drugs: beyond Lipinski's Rule GB Santos, A Ganesan, FS Emery ChemMedChem 11 (20), 2245-2251, 2016 | 131 | 2016 |
Azumamides A–E: Histone Deacetylase Inhibitory Cyclic Tetrapeptides from the Marine Sponge Mycale izuensis Y Nakao, S Yoshida, S Matsunaga, N Shindoh, Y Terada, K Nagai, ... Angewandte Chemie International Edition 45 (45), 7553-7557, 2006 | 131 | 2006 |
Epigenetic therapy: histone acetylation, DNA methylation and anti-cancer drug discovery A Ganesan, L Nolan, SJ Crabb, G Packham Current Cancer Drug Targets 9 (8), 963-981, 2009 | 129 | 2009 |
Ionic liquid acceleration of solid-phase Suzuki− Miyaura cross-coupling reactions JD Revell, A Ganesan Organic Letters 4 (18), 3071-3073, 2002 | 128 | 2002 |
The first biologically active synthetic analogues of FK228, the depsipeptide histone deacetylase inhibitor A Yurek-George, ARL Cecil, AHK Mo, S Wen, H Rogers, F Habens, ... Journal of medicinal chemistry 50 (23), 5720-5726, 2007 | 122 | 2007 |
Solution-phase synthesis of a β-amino alcohol combinatorial library BL Chng, A Ganesan Bioorganic & Medicinal Chemistry Letters 7 (12), 1511-1514, 1997 | 119 | 1997 |
Total Synthesis of the Fumiquinazoline Alkaloids: Solution-Phase Studies1 H Wang, A Ganesan The Journal of Organic Chemistry 65 (4), 1022-1030, 2000 | 110 | 2000 |