Advances in PEGylation of important biotech molecules: delivery aspects SM Ryan, G Mantovani, X Wang, DM Haddleton, DJ Brayden Expert opinion on drug delivery 5 (4), 371-383, 2008 | 397 | 2008 |
Antibacterial effects of poly (2-(dimethylamino ethyl) methacrylate) against selected gram-positive and gram-negative bacteria LAB Rawlinson, SM Ryan, G Mantovani, JA Syrett, DM Haddleton, ... Biomacromolecules 11 (2), 443-453, 2010 | 250 | 2010 |
Screening for and identification of starch-, amylopectin-, and pullulan-degrading activities in bifidobacterial strains SM Ryan, GF Fitzgerald, D van Sinderen Applied and environmental microbiology 72 (8), 5289-5296, 2006 | 222 | 2006 |
Direct peptide bioconjugation/PEGylation at tyrosine with linear and branched polymeric diazonium salts MW Jones, G Mantovani, CA Blindauer, SM Ryan, X Wang, DJ Brayden, ... Journal of the American Chemical Society 134 (17), 7406-7413, 2012 | 153 | 2012 |
Transcriptional Regulation and Characterization of a Novel β-Fructofuranosidase-Encoding Gene from Bifidobacterium breve UCC2003 SM Ryan, GF Fitzgerald, D van Sinderen Applied and environmental microbiology 71 (7), 3475-3482, 2005 | 126 | 2005 |
Characterization of ApuB, an Extracellular Type II Amylopullulanase from Bifidobacterium breve UCC2003 M O'Connell Motherway, GF Fitzgerald, S Neirynck, S Ryan, L Steidler, ... Applied and environmental microbiology 74 (20), 6271-6279, 2008 | 121 | 2008 |
Oral delivery strategies for nutraceuticals: Delivery vehicles and absorption enhancers JP Gleeson, SM Ryan, DJ Brayden Trends in Food Science & Technology 53, 90-101, 2016 | 117 | 2016 |
Phosphine-mediated one-pot thiol–ene “click” approach to polymer–protein conjugates MW Jones, G Mantovani, SM Ryan, X Wang, DJ Brayden, DM Haddleton Chemical communications, 5272-5274, 2009 | 107 | 2009 |
Conjugation of salmon calcitonin to a combed-shaped end functionalized poly (poly (ethylene glycol) methyl ether methacrylate) yields a bioactive stable conjugate SM Ryan, X Wang, G Mantovani, CT Sayers, DM Haddleton, DJ Brayden Journal of Controlled Release 135 (1), 51-59, 2009 | 94 | 2009 |
An intra-articular salmon calcitonin-based nanocomplex reduces experimental inflammatory arthritis SM Ryan, J McMorrow, A Umerska, HB Patel, KN Kornerup, L Tajber, ... Journal of controlled release 167 (2), 120-129, 2013 | 83 | 2013 |
Evaluation of PepT1 transport of food-derived antihypertensive peptides, Ile-Pro-Pro and Leu-Lys-Pro using in vitro, ex vivo and in vivo transport models JP Gleeson, DJ Brayden, SM Ryan European Journal of Pharmaceutics and Biopharmaceutics 115, 276-284, 2017 | 54 | 2017 |
Progress in the delivery of nanoparticle constructs: towards clinical translation SM Ryan, DJ Brayden Current opinion in pharmacology 18, 120-128, 2014 | 52 | 2014 |
In vitro and in vivo characterisation of a novel peptide delivery system: amphiphilic polyelectrolyte–salmon calcitonin nanocomplexes WP Cheng, C Thompson, SM Ryan, T Aguirre, L Tetley, DJ Brayden Journal of controlled release 147 (2), 289-297, 2010 | 51 | 2010 |
Stability, toxicity and intestinal permeation enhancement of two food-derived antihypertensive tripeptides, Ile-Pro-Pro and Leu-Lys-Pro JP Gleeson, J Heade, SM Ryan, DJ Brayden Peptides 71, 1-7, 2015 | 47 | 2015 |
Dexamethasone–pDMAEMA polymeric conjugates reduce inflammatory biomarkers in human intestinal epithelial monolayers S Keely, SM Ryan, DM Haddleton, A Limer, G Mantovani, EP Murphy, ... Journal of controlled release 135 (1), 35-43, 2009 | 47 | 2009 |
PK/PD modelling of comb-shaped PEGylated salmon calcitonin conjugates of differing molecular weights SM Ryan, JM Frías, X Wang, CT Sayers, DM Haddleton, DJ Brayden Journal of controlled release 149 (2), 126-132, 2011 | 37 | 2011 |
Site-specific N-terminus conjugation of poly (mPEG 1100) methacrylates to salmon calcitonin: synthesis and preliminary biological evaluation CT Sayers, G Mantovani, SM Ryan, RK Randev, O Keiper, ... Soft Matter 5 (16), 3038-3046, 2009 | 33 | 2009 |
Impact of amino acid replacements on in vitro permeation enhancement and cytotoxicity of the intestinal absorption promoter, melittin S Maher, M Devocelle, S Ryan, S McClean, DJ Brayden International journal of pharmaceutics 387 (1-2), 154-160, 2010 | 32 | 2010 |
Application of Box-Behnken experimental design for the formulation and optimisation of selenomethionine-loaded chitosan nanoparticles coated with zein for oral delivery G Vozza, M Danish, HJ Byrne, JM Frías, SM Ryan International journal of pharmaceutics 551 (1-2), 257-269, 2018 | 30 | 2018 |
Sodium caprate enables the blood pressure-lowering effect of Ile-Pro-Pro and Leu-Lys-Pro in spontaneously hypertensive rats by indirectly overcoming PepT1 inhibition JP Gleeson, JM Frías, SM Ryan, DJ Brayden European Journal of Pharmaceutics and Biopharmaceutics 128, 179-187, 2018 | 29 | 2018 |