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The library of integrated network-based cellular signatures NIH program: system-level cataloging of human cells response to perturbations AB Keenan, SL Jenkins, KM Jagodnik, S Koplev, E He, D Torre, Z Wang, ... Cell systems 6 (1), 13-24, 2018 | 405 | 2018 |
Macrophage Trafficking, Inflammatory Resolution, and Genomics in Atherosclerosis: JACC Macrophage in CVD Series (Part 2) KJ Moore, S Koplev, EA Fisher, I Tabas, JLM Björkegren, AC Doran, ... Journal of the American College of Cardiology 72 (18), 2181-2197, 2018 | 178 | 2018 |
Unraveling tumor–immune heterogeneity in advanced ovarian cancer uncovers immunogenic effect of chemotherapy A Jiménez-Sánchez, P Cybulska, KLV Mager, S Koplev, O Cast, ... Nature Genetics 52 (6), 582-593, 2020 | 175 | 2020 |
GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes N Franceschini, C Giambartolomei, PS De Vries, C Finan, JC Bis, ... Nature communications 9 (1), 5141, 2018 | 145 | 2018 |
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Sex-stratified gene regulatory networks reveal female key driver genes of atherosclerosis involved in smooth muscle cell phenotype switching RJG Hartman, K Owsiany, L Ma, S Koplev, K Hao, L Slenders, M Civelek, ... Circulation 143 (7), 713-726, 2021 | 79 | 2021 |
A strategy for discovery of endocrine interactions with application to whole-body metabolism MM Seldin, S Koplev, P Rajbhandari, L Vergnes, GM Rosenberg, Y Meng, ... Cell metabolism 27 (5), 1138-1155. e6, 2018 | 74 | 2018 |
Histone deacetylase 9 promotes endothelial-mesenchymal transition and an unfavorable atherosclerotic plaque phenotype L Lecce, Y Xu, B V’Gangula, N Chandel, V Pothula, A Caudrillier, ... The Journal of clinical investigation 131 (15), 2021 | 59 | 2021 |
Contribution of gene regulatory networks to heritability of coronary artery disease L Zeng, HA Talukdar, S Koplev, C Giannarelli, T Ivert, LM Gan, ... Journal of the American College of Cardiology 73 (23), 2946-2957, 2019 | 56 | 2019 |
A mechanistic framework for cardiometabolic and coronary artery diseases S Koplev, M Seldin, K Sukhavasi, R Ermel, S Pang, L Zeng, S Bankier, ... Nature Cardiovascular Research 1 (1), 85-100, 2022 | 55 | 2022 |
JCAD, a Gene at the 10p11 Coronary Artery Disease Locus, Regulates Hippo Signaling in Endothelial Cells PD Jones, MA Kaiser, M Ghaderi Najafabadi, S Koplev, Y Zhao, ... Arteriosclerosis, thrombosis, and vascular biology 38 (8), 1711-1722, 2018 | 51 | 2018 |
An integrative multiomic network model links lipid metabolism to glucose regulation in coronary artery disease AT Cohain, WT Barrington, DM Jordan, ND Beckmann, CA Argmann, ... Nature communications 12 (1), 547, 2021 | 45 | 2021 |
Functional regulatory mechanism of smooth muscle cell-restricted LMOD1 coronary artery disease locus V Nanda, T Wang, M Pjanic, B Liu, T Nguyen, LP Matic, U Hedin, ... PLoS genetics 14 (11), e1007755, 2018 | 41 | 2018 |
Integration of pan-cancer transcriptomics with RPPA proteomics reveals mechanisms of epithelial-mesenchymal transition S Koplev, K Lin, AB Dohlman, A Ma’ayan PLoS computational biology 14 (1), e1005911, 2018 | 37 | 2018 |
CD90 identifies adventitial mesenchymal progenitor cells in adult human medium-and large-sized arteries KC Michelis, A Nomura-Kitabayashi, L Lecce, O Franzén, S Koplev, Y Xu, ... Stem Cell Reports 11 (1), 242-257, 2018 | 32 | 2018 |
Transcriptome-wide association study of coronary artery disease identifies novel susceptibility genes L Li, Z Chen, M von Scheidt, S Li, A Steiner, U Güldener, S Koplev, A Ma, ... Basic research in cardiology 117 (1), 6, 2022 | 29 | 2022 |
Developing a framework for digital objects in the Big Data to Knowledge (BD2K) commons: Report from the Commons Framework Pilots workshop KM Jagodnik, S Koplev, SL Jenkins, L Ohno-Machado, B Paten, ... Journal of biomedical informatics 71, 49-57, 2017 | 29 | 2017 |
Functional and transcriptomic insights into pathogenesis of R9C phospholamban mutation using human induced pluripotent stem cell-derived cardiomyocytes DK Ceholski, IC Turnbull, CW Kong, S Koplev, J Mayourian, PA Gorski, ... Journal of molecular and cellular cardiology 119, 147-154, 2018 | 28 | 2018 |