关注
Simon Koplev
Simon Koplev
Teichmann lab, Sanger Institute, Cambridge PhD
在 cruk.cam.ac.uk 的电子邮件经过验证
标题
引用次数
引用次数
年份
Enrichr: a comprehensive gene set enrichment analysis web server 2016 update
MV Kuleshov, MR Jones, AD Rouillard, NF Fernandez, Q Duan, Z Wang, ...
Nucleic acids research 44 (W1), W90-W97, 2016
83982016
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes
R Malik, G Chauhan, M Traylor, M Sargurupremraj, Y Okada, A Mishra, ...
Nature genetics 50 (4), 524-537, 2018
13442018
The library of integrated network-based cellular signatures NIH program: system-level cataloging of human cells response to perturbations
AB Keenan, SL Jenkins, KM Jagodnik, S Koplev, E He, D Torre, Z Wang, ...
Cell systems 6 (1), 13-24, 2018
4052018
Macrophage Trafficking, Inflammatory Resolution, and Genomics in Atherosclerosis: JACC Macrophage in CVD Series (Part 2)
KJ Moore, S Koplev, EA Fisher, I Tabas, JLM Björkegren, AC Doran, ...
Journal of the American College of Cardiology 72 (18), 2181-2197, 2018
1782018
Unraveling tumor–immune heterogeneity in advanced ovarian cancer uncovers immunogenic effect of chemotherapy
A Jiménez-Sánchez, P Cybulska, KLV Mager, S Koplev, O Cast, ...
Nature Genetics 52 (6), 582-593, 2020
1752020
GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes
N Franceschini, C Giambartolomei, PS De Vries, C Finan, JC Bis, ...
Nature communications 9 (1), 5141, 2018
1452018
Clonally expanding smooth muscle cells promote atherosclerosis by escaping efferocytosis and activating the complement cascade
Y Wang, V Nanda, D Direnzo, J Ye, S Xiao, Y Kojima, KL Howe, KU Jarr, ...
Proceedings of the National Academy of Sciences 117 (27), 15818-15826, 2020
1012020
Sex-stratified gene regulatory networks reveal female key driver genes of atherosclerosis involved in smooth muscle cell phenotype switching
RJG Hartman, K Owsiany, L Ma, S Koplev, K Hao, L Slenders, M Civelek, ...
Circulation 143 (7), 713-726, 2021
792021
A strategy for discovery of endocrine interactions with application to whole-body metabolism
MM Seldin, S Koplev, P Rajbhandari, L Vergnes, GM Rosenberg, Y Meng, ...
Cell metabolism 27 (5), 1138-1155. e6, 2018
742018
Histone deacetylase 9 promotes endothelial-mesenchymal transition and an unfavorable atherosclerotic plaque phenotype
L Lecce, Y Xu, B V’Gangula, N Chandel, V Pothula, A Caudrillier, ...
The Journal of clinical investigation 131 (15), 2021
592021
Contribution of gene regulatory networks to heritability of coronary artery disease
L Zeng, HA Talukdar, S Koplev, C Giannarelli, T Ivert, LM Gan, ...
Journal of the American College of Cardiology 73 (23), 2946-2957, 2019
562019
A mechanistic framework for cardiometabolic and coronary artery diseases
S Koplev, M Seldin, K Sukhavasi, R Ermel, S Pang, L Zeng, S Bankier, ...
Nature Cardiovascular Research 1 (1), 85-100, 2022
552022
JCAD, a Gene at the 10p11 Coronary Artery Disease Locus, Regulates Hippo Signaling in Endothelial Cells
PD Jones, MA Kaiser, M Ghaderi Najafabadi, S Koplev, Y Zhao, ...
Arteriosclerosis, thrombosis, and vascular biology 38 (8), 1711-1722, 2018
512018
An integrative multiomic network model links lipid metabolism to glucose regulation in coronary artery disease
AT Cohain, WT Barrington, DM Jordan, ND Beckmann, CA Argmann, ...
Nature communications 12 (1), 547, 2021
452021
Functional regulatory mechanism of smooth muscle cell-restricted LMOD1 coronary artery disease locus
V Nanda, T Wang, M Pjanic, B Liu, T Nguyen, LP Matic, U Hedin, ...
PLoS genetics 14 (11), e1007755, 2018
412018
Integration of pan-cancer transcriptomics with RPPA proteomics reveals mechanisms of epithelial-mesenchymal transition
S Koplev, K Lin, AB Dohlman, A Ma’ayan
PLoS computational biology 14 (1), e1005911, 2018
372018
CD90 identifies adventitial mesenchymal progenitor cells in adult human medium-and large-sized arteries
KC Michelis, A Nomura-Kitabayashi, L Lecce, O Franzén, S Koplev, Y Xu, ...
Stem Cell Reports 11 (1), 242-257, 2018
322018
Transcriptome-wide association study of coronary artery disease identifies novel susceptibility genes
L Li, Z Chen, M von Scheidt, S Li, A Steiner, U Güldener, S Koplev, A Ma, ...
Basic research in cardiology 117 (1), 6, 2022
292022
Developing a framework for digital objects in the Big Data to Knowledge (BD2K) commons: Report from the Commons Framework Pilots workshop
KM Jagodnik, S Koplev, SL Jenkins, L Ohno-Machado, B Paten, ...
Journal of biomedical informatics 71, 49-57, 2017
292017
Functional and transcriptomic insights into pathogenesis of R9C phospholamban mutation using human induced pluripotent stem cell-derived cardiomyocytes
DK Ceholski, IC Turnbull, CW Kong, S Koplev, J Mayourian, PA Gorski, ...
Journal of molecular and cellular cardiology 119, 147-154, 2018
282018
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