Role of phospholipase C-ζ domains in Ca2+-dependent phosphatidylinositol 4, 5-bisphosphate hydrolysis and cytoplasmic Ca2+ oscillations M Nomikos, LM Blayney, MG Larman, K Campbell, A Rossbach, ... Journal of Biological Chemistry 280 (35), 31011-31018, 2005 | 182 | 2005 |
Phospholipase Cζ rescues failed oocyte activation in a prototype of male factor infertility M Nomikos, Y Yu, K Elgmati, M Theodoridou, K Campbell, ... Fertility and sterility 99 (1), 76-85, 2013 | 142 | 2013 |
Binding of phosphoinositide-specific phospholipase C-ζ (PLC-ζ) to phospholipid membranes: potential role of an unstructured cluster of basic residues M Nomikos, A Mulgrew-Nesbitt, P Pallavi, G Mihalyne, I Zaitseva, ... Journal of Biological Chemistry 282 (22), 16644-16653, 2007 | 117 | 2007 |
Starting a new life: Sperm PLC‐zeta mobilizes the Ca2+ signal that induces egg activation and embryo development: An essential phospholipase C with … M Nomikos, K Swann, FA Lai Bioessays 34 (2), 126-134, 2012 | 115 | 2012 |
PLCζ causes Ca2+ oscillations in mouse eggs by targeting intracellular and not plasma membrane PI(4,5)P2 Y Yu, M Nomikos, M Theodoridou, G Nounesis, FA Lai, K Swann Molecular biology of the cell 23 (2), 371-380, 2012 | 102 | 2012 |
Sperm PLCζ: from structure to Ca2+ oscillations, egg activation and therapeutic potential M Nomikos, J Kashir, K Swann, FA Lai FEBS letters 587 (22), 3609-3616, 2013 | 94 | 2013 |
Sperm-induced Ca2+ release during egg activation in mammals J Kashir, M Nomikos, FA Lai, K Swann Biochemical and biophysical research communications 450 (3), 1204-1211, 2014 | 86 | 2014 |
Rescue of failed oocyte activation after ICSI in a mouse model of male factor infertility by recombinant phospholipase Cζ R Sanusi, Y Yu, M Nomikos, FA Lai, K Swann MHR: Basic science of reproductive medicine 21 (10), 783-791, 2015 | 85 | 2015 |
Phospholipase Cζ binding to PtdIns(4,5)P2 requires the XY-linker region M Nomikos, K Elgmati, M Theodoridou, BL Calver, G Nounesis, K Swann, ... Journal of cell science 124 (15), 2582-2590, 2011 | 83 | 2011 |
Sperm-specific post-acrosomal WW-domain binding protein (PAWP) does not cause Ca2+ release in mouse oocytes M Nomikos, JR Sanders, M Theodoridou, J Kashir, E Matthews, ... MHR: Basic science of reproductive medicine 20 (10), 938-947, 2014 | 79 | 2014 |
Novel regulation of PLCζ activity via its XY-linker M Nomikos, K Elgmati, M Theodoridou, A Georgilis, JR Gonzalez-Garcia, ... Biochemical Journal 438 (3), 427-432, 2011 | 71 | 2011 |
Phospholipase C-ζ-induced Ca2+ oscillations cause coincident cytoplasmic movements in human oocytes that failed to fertilize after intracytoplasmic sperm injection K Swann, S Windsor, K Campbell, K Elgmati, M Nomikos, ... Fertility and sterility 97 (3), 742-747, 2012 | 70 | 2012 |
Male infertility-linked point mutation disrupts the Ca2+ oscillation-inducing and PIP2 hydrolysis activity of sperm PLCζ M Nomikos, K Elgmati, M Theodoridou, BL Calver, B Cumbes, ... Biochemical Journal 434 (2), 211-217, 2011 | 69 | 2011 |
Essential role of sperm-specific PLC-zeta in egg activation and male factor infertility: an update A Saleh, J Kashir, A Thanassoulas, B Safieh-Garabedian, FA Lai, ... Frontiers in cell and developmental biology 8, 28, 2020 | 64 | 2020 |
Expression of sperm PLCζ and clinical outcomes of ICSI-AOA in men affected by globozoospermia due to DPY19L2 deletion M Tavalaee, M Nomikos, FA Lai, MH Nasr-Esfahani Reproductive biomedicine online 36 (3), 348-355, 2018 | 60 | 2018 |
Functional disparity between human PAWP and PLCζ in the generation of Ca2+ oscillations for oocyte activation M Nomikos, JR Sanders, J Kashir, R Sanusi, L Buntwal, D Love, P Ashley, ... MHR: Basic science of reproductive medicine 21 (9), 702-710, 2015 | 56 | 2015 |
The role and mechanism of action of sperm PLC-zeta in mammalian fertilisation M Nomikos, J Kashir, FA Lai Biochemical Journal 474 (21), 3659-3673, 2017 | 50 | 2017 |
Antigen unmasking enhances visualization efficacy of the oocyte activation factor, phospholipase C zeta, in mammalian sperm J Kashir, L Buntwal, M Nomikos, BL Calver, P Stamatiadis, P Ashley, ... MHR: Basic science of reproductive medicine 23 (1), 54-67, 2017 | 47 | 2017 |
Distinctive malfunctions of calmodulin mutations associated with heart RyR2-mediated arrhythmic disease V Vassilakopoulou, BL Calver, A Thanassoulas, K Beck, H Hu, L Buntwal, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1850 (11), 2168-2176, 2015 | 47 | 2015 |
Essential role of the EF-hand domain in targeting sperm phospholipase Cζ to membrane phosphatidylinositol 4, 5-bisphosphate (PIP2) M Nomikos, JR Sanders, D Parthimos, L Buntwal, BL Calver, ... Journal of Biological Chemistry 290 (49), 29519-29530, 2015 | 45 | 2015 |