| A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function S Feske, Y Gwack, M Prakriya, S Srikanth, SH Puppel, B Tanasa, ... Nature 441 (7090), 179-185, 2006 | 2679 | 2006 |
| Orai1 is an essential pore subunit of the CRAC channel M Prakriya, S Feske, Y Gwack, S Srikanth, A Rao, PG Hogan Nature 443 (7108), 230-233, 2006 | 1650 | 2006 |
| A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT Y Gwack, S Sharma, J Nardone, B Tanasa, A Iuga, S Srikanth, H Okamura, ... Nature 441 (7093), 646-650, 2006 | 490 | 2006 |
| Biochemical and functional characterization of Orai proteins Y Gwack, S Srikanth, S Feske, F Cruz-Guilloty, M Oh-hora, DS Neems, ... Journal of Biological Chemistry 282 (22), 16232-16243, 2007 | 489 | 2007 |
| Dynamic assembly of TRPC1-STIM1-Orai1 ternary complex is involved in store-operated calcium influx: evidence for similarities in store-operated and calcium release-activated … HL Ong, KT Cheng, X Liu, BC Bandyopadhyay, BC Paria, J Soboloff, ... Journal of Biological Chemistry 282 (12), 9105-9116, 2007 | 451 | 2007 |
| Signalling to transcription: store-operated Ca2+ entry and NFAT activation in lymphocytes Y Gwack, S Feske, S Srikanth, PG Hogan, A Rao Cell calcium 42 (2), 145-156, 2007 | 401 | 2007 |
| Hair loss and defective T-and B-cell function in mice lacking ORAI1 Y Gwack, S Srikanth, M Oh-Hora, PG Hogan, ED Lamperti, M Yamashita, ... Molecular and cellular biology, 2008 | 350 | 2008 |
| The Ca2+ sensor STIM1 regulates the type I interferon response by retaining the signaling adaptor STING at the endoplasmic reticulum S Srikanth, JS Woo, B Wu, YM El-Sherbiny, J Leung, K Chupradit, L Rice, ... Nature immunology 20 (2), 152-162, 2019 | 276 | 2019 |
| A novel EF-hand protein, CRACR2A, is a cytosolic Ca2+ sensor that stabilizes CRAC channels in T cells S Srikanth, HJ Jung, KD Kim, P Souda, J Whitelegge, Y Gwack Nature cell biology 12 (5), 436-446, 2010 | 275 | 2010 |
| The ion channel TRPV1 regulates the activation and proinflammatory properties of CD4+ T cells S Bertin, Y Aoki-Nonaka, PR De Jong, LL Nohara, H Xu, SR Stanwood, ... Nature immunology 15 (11), 1055-1063, 2014 | 252 | 2014 |
| Dynamic movement of the calcium sensor STIM1 and the calcium channel Orai1 in activated T-cells: puncta and distal caps VA Barr, KM Bernot, S Srikanth, Y Gwack, L Balagopalan, CK Regan, ... Molecular biology of the cell 19 (7), 2802-2817, 2008 | 169 | 2008 |
| Junctate is a Ca2+-sensing structural component of Orai1 and stromal interaction molecule 1 (STIM1) S Srikanth, M Jew, KD Kim, MK Yee, J Abramson, Y Gwack Proceedings of the National Academy of Sciences 109 (22), 8682-8687, 2012 | 137 | 2012 |
| Laminar flow downregulates Notch activity to promote lymphatic sprouting D Choi, E Park, E Jung, YJ Seong, J Yoo, E Lee, M Hong, S Lee, H Ishida, ... The Journal of clinical investigation 127 (4), 1225-1240, 2017 | 127 | 2017 |
| Orai1-NFAT signalling pathway triggered by T cell receptor stimulation S Srikanth, Y Gwack Molecules and cells 35 (3), 182-194, 2013 | 113 | 2013 |
| Interplay between the oxidoreductase PDIA6 and microRNA-322 controls the response to disrupted endoplasmic reticulum calcium homeostasis J Groenendyk, Z Peng, E Dudek, X Fan, MJ Mizianty, E Dufey, H Urra, ... Science signaling 7 (329), ra54-ra54, 2014 | 111 | 2014 |
| The Intracellular Loop of Orai1 Plays a Central Role in Fast Inactivation of Ca2+ Release-activated Ca2+ Channels 2 S Srikanth, HJ Jung, B Ribalet, Y Gwack Journal of Biological Chemistry 285 (7), 5066-5075, 2010 | 99 | 2010 |
| ORAI1 deficiency impairs activated T cell death and enhances T cell survival KD Kim, S Srikanth, MKW Yee, DC Mock, GW Lawson, Y Gwack The Journal of Immunology 187 (7), 3620-3630, 2011 | 87 | 2011 |
| Calcium signaling via Orai1 is essential for induction of the nuclear orphan receptor pathway to drive Th17 differentiation KD Kim, S Srikanth, YV Tan, MK Yee, M Jew, R Damoiseaux, ME Jung, ... The Journal of Immunology 192 (1), 110-122, 2014 | 80 | 2014 |
| Orai1, STIM1, and their associating partners S Srikanth, Y Gwack The Journal of physiology 590 (17), 4169-4177, 2012 | 75 | 2012 |
| ORAI1 activates proliferation of lymphatic endothelial cells in response to laminar flow through Krüppel-like factors 2 and 4 D Choi, E Park, E Jung, YJ Seong, M Hong, S Lee, J Burford, G Gyarmati, ... Circulation research 120 (9), 1426-1439, 2017 | 71 | 2017 |
