| A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation G Timinszky, S Till, PO Hassa, M Hothorn, G Kustatscher, B Nijmeijer, ... Nature structural & molecular biology 16 (9), 923-929, 2009 | 493 | 2009 |
| Poly (ADP-ribosyl) ation directs recruitment and activation of an ATP-dependent chromatin remodeler AJ Gottschalk, G Timinszky, SE Kong, J Jin, Y Cai, SK Swanson, ... Proceedings of the National Academy of Sciences 106 (33), 13770-13774, 2009 | 411 | 2009 |
| A family of macrodomain proteins reverses cellular mono-ADP-ribosylation G Jankevicius, M Hassler, B Golia, V Rybin, M Zacharias, G Timinszky, ... Nature structural & molecular biology 20 (4), 508-514, 2013 | 347 | 2013 |
| Deficiency of terminal ADP‐ribose protein glycohydrolase TARG1/C6orf130 in neurodegenerative disease R Sharifi, R Morra, C Denise Appel, M Tallis, B Chioza, G Jankevicius, ... The EMBO journal 32 (9), 1225-1237, 2013 | 322 | 2013 |
| The zinc-finger domains of PARP1 cooperate to recognize DNA strand breaks AAE Ali, G Timinszky, R Arribas-Bosacoma, M Kozlowski, PO Hassa, ... Nature structural & molecular biology 19 (7), 685-692, 2012 | 315 | 2012 |
| Structures of Drosophila cryptochrome and mouse cryptochrome1 provide insight into circadian function A Czarna, A Berndt, HR Singh, A Grudziecki, AG Ladurner, G Timinszky, ... Cell 153 (6), 1394-1405, 2013 | 214 | 2013 |
| ADP‐ribosyltransferases, an update on function and nomenclature B Lüscher, I Ahel, M Altmeyer, A Ashworth, P Bai, P Chang, M Cohen, ... The FEBS journal 289 (23), 7399-7410, 2022 | 201 | 2022 |
| The recognition and removal of cellular poly (ADP‐ribose) signals E Barkauskaite, G Jankevicius, AG Ladurner, I Ahel, G Timinszky The FEBS journal 280 (15), 3491-3507, 2013 | 143 | 2013 |
| The poly (ADP-ribose)-dependent chromatin remodeler Alc1 induces local chromatin relaxation upon DNA damage H Sellou, T Lebeaupin, C Chapuis, R Smith, A Hegele, HR Singh, ... Molecular biology of the cell 27 (24), 3791-3799, 2016 | 122 | 2016 |
| A poly-ADP-ribose trigger releases the auto-inhibition of a chromatin remodeling oncogene HR Singh, AP Nardozza, IR Möller, G Knobloch, HAV Kistemaker, ... Molecular cell 68 (5), 860-871. e7, 2017 | 90 | 2017 |
| The chromatin remodeler ALC1 underlies resistance to PARP inhibitor treatment S Juhász, R Smith, T Schauer, D Spekhardt, H Mamar, S Zentout, ... Science advances 6 (51), eabb8626, 2020 | 80 | 2020 |
| MacroH2A histone variants limit chromatin plasticity through two distinct mechanisms M Kozlowski, D Corujo, M Hothorn, I Guberovic, IK Mandemaker, ... EMBO reports 19 (10), e44445, 2018 | 65 | 2018 |
| CHD3 and CHD4 recruitment and chromatin remodeling activity at DNA breaks is promoted by early poly (ADP-ribose)-dependent chromatin relaxation R Smith, H Sellou, C Chapuis, S Huet, G Timinszky Nucleic acids research 46 (12), 6087-6098, 2018 | 63 | 2018 |
| Poly (ADP-ribose)-dependent chromatin unfolding facilitates the association of DNA-binding proteins with DNA at sites of damage R Smith, T Lebeaupin, S Juhász, C Chapuis, O D’Augustin, S Dutertre, ... Nucleic acids research 47 (21), 11250-11267, 2019 | 61 | 2019 |
| The importin-β P446L dominant-negative mutant protein loses RanGTP binding ability and blocks the formation of intact nuclear envelope G Timinszky, L Tirián, FT Nagy, G Tóth, A Perczel, Z Kiss-László, I Boros, ... Journal of cell science 115 (8), 1675-1687, 2002 | 51 | 2002 |
| Macro domains as metabolite sensors on chromatin M Posavec, G Timinszky, M Buschbeck Cellular and Molecular Life Sciences 70, 1509-1524, 2013 | 50 | 2013 |
| Targeting actin inhibits repair of doxorubicin-induced DNA damage: a novel therapeutic approach for combination therapy L Pfitzer, C Moser, F Gegenfurtner, A Arner, F Foerster, C Atzberger, ... Cell death & disease 10 (4), 302, 2019 | 38 | 2019 |
| Repression of RNA polymerase II transcription by a Drosophila oligopeptide G Timinszky, M Bortfeld, AG Ladurner PLoS One 3 (6), e2506, 2008 | 34 | 2008 |
| Poly-ADP-ribosylation signaling during DNA damage repair B Golia, HR Singh, G Timinszky Front. Biosci 20, 440-457, 2015 | 31 | 2015 |
| HPF1-dependent histone ADP-ribosylation triggers chromatin relaxation to promote the recruitment of repair factors at sites of DNA damage R Smith, S Zentout, M Rother, N Bigot, C Chapuis, A Mihuț, FF Zobel, ... Nature Structural & Molecular Biology 30 (5), 678-691, 2023 | 29 | 2023 |
Andreas LadurnerChair of Physiological Chemistry, LMU Munich; Founder, Managing Director and CSO, Eisbach Bio GmbH在 med.lmu.de 的电子邮件经过验证
