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Mohammad Alzrigat
Mohammad Alzrigat
在 ki.se 的电子邮件经过验证
标题
引用次数
引用次数
年份
Epigenetics in multiple myeloma: From mechanisms to therapy
M Alzrigat, AA Párraga, H Jernberg-Wiklund
Seminars in cancer biology 51, 101-115, 2018
922018
PML promotes MHC class II gene expression by stabilizing the class II transactivator
T Ulbricht, M Alzrigat, A Horch, N Reuter, A von Mikecz, V Steimle, ...
The Journal of cell biology 199 (1), 49, 2012
742012
Genome-wide profiling of histone H3 lysine 27 and lysine 4 trimethylation in multiple myeloma reveals the importance of Polycomb gene targeting and highlights EZH2 as a …
P Agarwal, M Alzrigat, AA Párraga, S Enroth, U Singh, J Ungerstedt, ...
Oncotarget 7 (6), 6809, 2016
712016
EZH2 inhibition in multiple myeloma downregulates myeloma associated oncogenes and upregulates microRNAs with potential tumor suppressor functions
M Alzrigat, AA Párraga, P Agarwal, H Zureigat, A Österborg, H Nahi, A Ma, ...
Oncotarget 8 (6), 10213, 2017
622017
The polycomb group protein BMI-1 inhibitor PTC-209 is a potent anti-myeloma agent alone or in combination with epigenetic inhibitors targeting EZH2 and the BET bromodomains
M Alzrigat, AA Párraga, MM Majumder, A Ma, J Jin, A Österborg, H Nahi, ...
Oncotarget 8 (61), 103731, 2017
262017
Targeting EZH2 in multiple myeloma—multifaceted anti-tumor activity
M Alzrigat, H Jernberg-Wiklund, JD Licht
Epigenomes 2 (3), 16, 2018
232018
The miR-125a and miR-320c are potential tumor suppressor microRNAs epigenetically silenced by the polycomb repressive complex 2 in multiple myeloma
M Alzrigat, H Jernberg-Wiklund
RNA & Disease (Houston, Tex.) 4 (2), 2017
212017
MYC Inhibition Halts Metastatic Breast Cancer Progression by Blocking Growth, Invasion, and Seeding
D Massó-Vallés, ME Beaulieu, T Jauset, F Giuntini, MF Zacarías-Fluck, ...
Cancer Research Communications 2 (2), 110–130, 2022
182022
HIF-1 stabilization in T cells hampers the control of Mycobacterium tuberculosis infection
R Liu, V Muliadi, W Mou, H Li, J Yuan, J Holmberg, BJ Chambers, N Ullah, ...
nature communications 13 (1), 5093, 2022
162022
Pharmacological inactivation of CDK2 inhibits MYC/BCL-XL-driven leukemia in vivo through induction of cellular senescence
W Bazzar, M Bocci, E Hejll, V Högqvist Tabor, P Hydbring, A Grandien, ...
Cell Cycle 20 (1), 23-38, 2021
122021
MYCMI-7: a small MYC-binding compound that inhibits MYC: MAX interaction and tumor growth in a MYC-dependent manner
A Castell, Q Yan, K Fawkner, W Bazzar, F Zhang, M Wickström, M Alzrigat, ...
Cancer Research Communications 2 (3), 182-201, 2022
102022
Methods to study myc-regulated Cellular Senescence: an update
F Zhang, W Bazzar, M Alzrigat, LG Larsson
The Myc Gene: Methods and Protocols, 241-254, 2021
62021
MYCN amplification is associated with reduced expression of genes encoding γ-secretase complex and NOTCH signaling components in neuroblastoma
P Agarwal, A Glowacka, L Mahmoud, W Bazzar, LG Larsson, M Alzrigat
International Journal of Molecular Sciences 24 (9), 8141, 2023
32023
Target Genes of c-MYC and MYCN with Prognostic Power in Neuroblastoma Exhibit Different Expressions during Sympathoadrenal Development
Y Yuan, M Alzrigat, A Rodriguez-Garcia, X Wang, TS Bexelius, JI Johnsen, ...
Cancers 15 (18), 4599, 2023
12023
Targeted Epigenetic Therapy: EZH2 Inhibition in B-cell Malignancies
M Alzrigat
EC Proteomics and Bioinformatics ECO 1, 07-10, 2017
2017
Targeted Inhibition of Polycomb Repressive Complexes in Multiple Myeloma: Implications for Biology and Therapy
M Alzrigat
Acta Universitatis Upsaliensis, 2017
2017
IKKα contains two conserved LXXLL co-activator motifs and is recruited to the retinoic acid receptor
A Kalushkova, H Göransson Kultima, F Zhang, M Alzrigat, P Agarwal, ...
2013
The role of the inhibitor of B kinase alpha (IKK) in epigenetic changes mediated by RAR-RXR nuclear receptor-activated transcription
M Alzrigat
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