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Karen Chapman
Karen Chapman
在 ed.ac.uk 的电子邮件经过验证
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引用次数
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The anti-inflammatory and immunosuppressive effects of glucocorticoids, recent developments and mechanistic insights
AE Coutinho, KE Chapman
Molecular and cellular endocrinology 335 (1), 2-13, 2011
18972011
11β-hydroxysteroid dehydrogenases: intracellular gate-keepers of tissue glucocorticoid action
K Chapman, M Holmes, J Seckl
Physiological reviews 93 (3), 1139-1206, 2013
8802013
11 beta-hydroxysteroid dehydrogenase is an exclusive 11 beta-reductase in primary cultures of rat hepatocytes: effect of physicochemical and hormonal manipulations
PM Jamieson, KE Chapman, CR Edwards, JR Seckl
Endocrinology 136 (11), 4754-4761, 1995
4031995
Human placental 11 beta-hydroxysteroid dehydrogenase: evidence for and partial purification of a distinct NAD-dependent isoform
RW Brown, KE Chapman, CR Edwards, JR Seckl
Endocrinology 132 (6), 2614-2621, 1993
3591993
Postnatal handling increases the expression of cAMP-inducible transcription factors in the rat hippocampus: the effects of thyroid hormones and serotonin
MJ Meaney, J Diorio, D Francis, S Weaver, J Yau, K Chapman, JR Seckl
Journal of Neuroscience 20 (10), 3926-3935, 2000
3232000
Glucocorticoids and 11beta-hydroxysteroid dehydrogenase in adipose tissue
JR Seckl, NM Morton, KE Chapman, BR Walker
Recent progress in hormone research 59, 359-394, 2004
3192004
5′-heterogeneity of glucocorticoid receptor messenger RNA is tissue specific: differential regulation of variant transcripts by early-life events
JA McCormick, V Lyons, MD Jacobson, J Noble, J Diorio, M Nyirenda, ...
Molecular endocrinology 14 (4), 506-517, 2000
3112000
Mineralocorticoid and glucocorticoid receptor balance in control of HPA axis and behaviour
AP Harris, MC Holmes, ER De Kloet, KE Chapman, JR Seckl
Psychoneuroendocrinology 38 (5), 648-658, 2013
2662013
Mutations that alter the ability of the Escherichia coli cyclic AMP receptor protein to activate transcription
A Bell, K Gaston, R Williams, K Chapman, A Kolb, H Buc, S Minchin, ...
Nucleic acids research 18 (24), 7243-7250, 1990
2381990
Cloning and production of antisera to human placental 11 β-hydroxysteroid dehydrogenase type 2
RW BROWN, KE CHAPMAN, Y KOTELEVTSEV, JLW YAU, RS LINDSAY, ...
Biochemical Journal 313 (3), 1007-1017, 1996
2141996
Hexose-6-phosphate dehydrogenase confers oxo-reductase activity upon 11β-hydroxysteroid dehydrogenase type 1
IJ Bujalska, N Draper, Z Michailidou, JW Tomlinson, PC White, ...
Journal of molecular endocrinology 34 (3), 675-684, 2005
2062005
High titers of transmissible spongiform encephalopathy infectivity associated with extremely low levels of PrPSc in vivo
RM Barron, SL Campbell, D King, A Bellon, KE Chapman, RA Williamson, ...
Journal of Biological Chemistry 282 (49), 35878-35886, 2007
1892007
Local amplification of glucocorticoids by 11β-hydroxysteroid dehydrogenase type 1 promotes macrophage phagocytosis of apoptotic leukocytes
JS Gilmour, AE Coutinho, JF Cailhier, TY Man, M Clay, G Thomas, ...
The Journal of Immunology 176 (12), 7605-7611, 2006
1832006
Glucocorticoid receptor is required for foetal heart maturation
EA Rog-Zielinska, A Thomson, CJ Kenyon, DG Brownstein, CM Moran, ...
Human molecular genetics 22 (16), 3269-3282, 2013
1692013
11β-Hydroxysteroid dehydrogenase 1 in adipocytes: expression is differentiation-dependent and hormonally regulated
A Napolitano, MW Voice, CRW Edwards, JR Seckl, KE Chapman
The Journal of Steroid Biochemistry and Molecular Biology 64 (5-6), 251-260, 1998
1581998
C/EBP regulates hepatic transcription of 11β-hydroxysteroid dehydrogenase type 1: a novel mechanism for cross-talk between the C/EBP and glucocorticoid signaling pathways
LJS Williams, V Lyons, I MacLeod, V Rajan, GJ Darlington, V Poli, ...
Journal of Biological Chemistry 275 (39), 30232-30239, 2000
1562000
Early environmental regulation of hippocampal glucocorticoid receptor gene expression: characterization of intracellular mediators and potential genomic target sites
ICG Weaver, P La Plante, S Weaver, A Parent, S Sharma, J Diorio, ...
Molecular and cellular endocrinology 185 (1-2), 205-218, 2001
1542001
Changing glucocorticoid action: 11β-hydroxysteroid dehydrogenase type 1 in acute and chronic inflammation
KE Chapman, AE Coutinho, Z Zhang, T Kipari, JS Savill, JR Seckl
The Journal of steroid biochemistry and molecular biology 137, 82-92, 2013
1482013
'Liver-type'11β-hydroxysteroid dehydrogenase cDNA encodes reductase but not dehydrogenase activity in intact mammalian COS-7 cells
SC Low, KE Chapman, CRW Edwards, JR Seckl
Journal of Molecular Endocrinology 13 (2), 167-174, 1994
1441994
Regulation of the initiation of eukaryotic transcription.
G Gill
Essays in biochemistry 37, 33-43, 2001
1432001
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