The Nrd1–Nab3–Sen1 termination complex interacts with the Ser5-phosphorylated RNA polymerase II C-terminal domain L Vasiljeva, M Kim, H Mutschler, S Buratowski, A Meinhart Nature structural & molecular biology 15 (8), 795-804, 2008 | 353 | 2008 |
MaxSynBio: avenues towards creating cells from the bottom up P Schwille, J Spatz, K Landfester, E Bodenschatz, S Herminghaus, ... Angewandte Chemie International Edition 57 (41), 13382-13392, 2018 | 277 | 2018 |
Compartmentalised RNA catalysis in membrane-free coacervate protocells B Drobot, JM Iglesias-Artola, K Le Vay, V Mayr, M Kar, M Kreysing, ... Nature Communications 9 (1), 2018 | 265 | 2018 |
A novel mechanism of programmed cell death in bacteria by toxin–antitoxin systems corrupts peptidoglycan synthesis H Mutschler, M Gebhardt, RL Shoeman, A Meinhart PLoS biology 9 (3), e1001033, 2011 | 262 | 2011 |
Cooperative interaction of transcription termination factors with the RNA polymerase II C-terminal domain BM Lunde, SL Reichow, M Kim, H Suh, TC Leeper, F Yang, H Mutschler, ... Nature structural & molecular biology 17 (10), 1195-1201, 2010 | 199 | 2010 |
Active coacervate droplets as a model for membraneless organelles and protocells C Donau, F Späth, M Sosson, BAK Kriebisch, F Schnitter, ... Nature communications 11 (1), 5167, 2020 | 171 | 2020 |
Freeze–thaw cycles as drivers of complex ribozyme assembly H Mutschler, A Wochner, P Holliger Nature Chemistry 7 (6), 502-508, 2015 | 135 | 2015 |
ε/ζ systems: their role in resistance, virulence, and their potential for antibiotic development H Mutschler, A Meinhart Journal of molecular medicine 89, 1183-1194, 2011 | 92 | 2011 |
Heated gas bubbles enrich, crystallize, dry, phosphorylate and encapsulate prebiotic molecules M Morasch, J Liu, CF Dirscherl, A Ianeselli, A Kühnlein, K Le Vay, ... Nature Chemistry 11 (9), 779-788, 2019 | 86 | 2019 |
In vitro self-replication and multicistronic expression of large synthetic genomes K Libicher, R Hornberger, M Heymann, H Mutschler Nature Communications 11 (1), 904, 2020 | 70 | 2020 |
Both ATPase domains of ClpA are critical for processing of stable protein structures W Kress, H Mutschler, E Weber-Ban Journal of biological chemistry 284 (45), 31441-31452, 2009 | 56 | 2009 |
Freeze-thaw cycles induce content exchange between cell-sized lipid vesicles T Litschel, KA Ganzinger, T Movinkel, M Heymann, T Robinson, ... New Journal of Physics 20 (5), 055008, 2018 | 53 | 2018 |
Charge-density reduction promotes ribozyme activity in RNA–peptide coacervates via RNA fluidization and magnesium partitioning JM Iglesias-Artola, B Drobot, M Kar, AW Fritsch, H Mutschler, ... Nature chemistry 14 (4), 407-416, 2022 | 48 | 2022 |
Assembly pathway of an AAA+ protein: tracking ClpA and ClpAP complex formation in real time W Kress, H Mutschler, E Weber-Ban Biochemistry 46 (21), 6183-6193, 2007 | 47 | 2007 |
Random-sequence genetic oligomer pools display an innate potential for ligation and recombination H Mutschler, AI Taylor, BT Porebski, A Lightowlers, G Houlihan, ... Elife 7, e43022, 2018 | 41 | 2018 |
Assembly dynamics and stability of the pneumococcal epsilon zeta antitoxin toxin (PezAT) system from Streptococcus pneumoniae H Mutschler, J Reinstein, A Meinhart Journal of biological chemistry 285 (28), 21797-21806, 2010 | 40 | 2010 |
The difficult case of an RNA-only origin of life K Le Vay, H Mutschler Emerging Topics in Life Sciences, ETLS20190024, 2019 | 39 | 2019 |
Enhanced ribozyme-catalyzed recombination and oligonucleotide assembly in peptide-RNA condensates KK Le Vay, EY Song, B Ghosh, TYD Tang, H Mutschler Angewandte Chemie International Edition, 2021 | 31 | 2021 |
Non-canonical 3’-5’extension of RNA with prebiotically plausible ribonucleoside 2’, 3’-cyclic phosphates H Mutschler, P Holliger Journal of the American Chemical Society 136 (14), 5193–5196, 2014 | 29 | 2014 |
Templated Self‐Replication in Biomimetic Systems KL Vay, LI Weise, K Libicher, J Mascarenhas, H Mutschler Advanced Biosystems, 1800313, 2019 | 27 | 2019 |