MEK drives BRAF activation through allosteric control of KSR proteins H Lavoie, M Sahmi, P Maisonneuve, SA Marullo, N Thevakumaran, T Jin, ... Nature 554 (7693), 549-553, 2018 | 128 | 2018 |
Functional characterization of a PROTAC directed against BRAF mutant V600E G Posternak, X Tang, P Maisonneuve, T Jin, H Lavoie, S Daou, S Orlicky, ... Nature chemical biology 16 (11), 1170-1178, 2020 | 105 | 2020 |
Proteomic analysis of the human KEOPS complex identifies C14ORF142 as a core subunit homologous to yeast Gon7 LCK Wan, P Maisonneuve, RK Szilard, JP Lambert, TF Ng, N Manczyk, ... Nucleic acids research 45 (2), 805-817, 2017 | 59 | 2017 |
Strategies to interfere with PDZ-mediated interactions in neurons: What we can learn from the rabies virus C Caillet-Saguy, P Maisonneuve, F Delhommel, E Terrien, N Babault, ... Progress in biophysics and molecular biology 119 (1), 53-59, 2015 | 36 | 2015 |
Bora phosphorylation substitutes in trans for T-loop phosphorylation in Aurora A to promote mitotic entry N Tavernier, Y Thomas, S Vigneron, P Maisonneuve, S Orlicky, P Mader, ... Nature communications 12 (1), 1899, 2021 | 28 | 2021 |
Discovery and structural characterization of small molecule binders of the human CTLH E3 ligase subunit GID4 CK Chana, P Maisonneuve, G Posternak, NGA Grinberg, J Poirson, ... Journal of medicinal chemistry 65 (19), 12725-12746, 2022 | 26 | 2022 |
A substrate binding model for the KEOPS tRNA modifying complex J Beenstock, SM Ona, J Porat, S Orlicky, LCK Wan, DF Ceccarelli, ... Nature communications 11 (1), 6233, 2020 | 25 | 2020 |
Regulation of the catalytic activity of the human phosphatase PTPN 4 by its PDZ domain P Maisonneuve, C Caillet‐Saguy, B Raynal, B Gilquin, A Chaffotte, ... The FEBS Journal 281 (21), 4852-4865, 2014 | 23 | 2014 |
Molecular basis of the interaction of the human protein tyrosine phosphatase non-receptor type 4 (PTPN4) with the mitogen-activated protein kinase p38γ P Maisonneuve, C Caillet-Saguy, MC Vaney, E Bibi-Zainab, K Sawyer, ... Journal of Biological Chemistry 291 (32), 16699-16708, 2016 | 22 | 2016 |
High accuracy prediction of PROTAC complex structures M Ignatov, A Jindal, S Kotelnikov, D Beglov, G Posternak, X Tang, ... Journal of the American Chemical Society 145 (13), 7123-7135, 2023 | 16 | 2023 |
Effects of rigidity on the selectivity of protein kinase inhibitors A Assadieskandar, C Yu, P Maisonneuve, X Liu, YC Chen, GKS Prakash, ... European journal of medicinal chemistry 146, 519-528, 2018 | 16 | 2018 |
Conformation-specific inhibitors of activated Ras GTPases reveal limited Ras dependency of patient-derived cancer organoids S Wiechmann, P Maisonneuve, BM Grebbin, M Hoffmeister, M Kaulich, ... Journal of Biological Chemistry 295 (14), 4526-4540, 2020 | 15 | 2020 |
Rigidification dramatically improves inhibitor selectivity for RAF kinases A Assadieskandar, C Yu, P Maisonneuve, I Kurinov, F Sicheri, C Zhang ACS Medicinal Chemistry Letters 10 (7), 1074-1080, 2019 | 14 | 2019 |
FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane DF Ceccarelli, S Ivantsiv, AA Mullin, E Coyaud, N Manczyk, ... Structure 27 (6), 1000-1012. e6, 2019 | 13 | 2019 |
Regulation of the Human Phosphatase PTPN4 by the inter-domain linker connecting the PDZ and the phosphatase domains C Caillet-Saguy, A Toto, R Guerois, P Maisonneuve, E Di Silvio, K Sawyer, ... Scientific reports 7 (1), 7875, 2017 | 12 | 2017 |
Automatic Bayesian weighting for SAXS data YG Spill, Y Karami, P Maisonneuve, N Wolff, M Nilges Frontiers in Molecular Biosciences 8, 671011, 2021 | 3 | 2021 |
The CNK–HYP scaffolding complex promotes RAF activation by enhancing KSR–MEK interaction P Maisonneuve, M Sahmi, F Bergeron-Labrecque, XI Ma, J Queguiner, ... Nature Structural & Molecular Biology, 1-11, 2024 | | 2024 |
The evolutionary divergence of receptor guanylyl cyclase C has implications for preclinical models for receptor-directed therapeutics V Mishra, K Sharma, A Bose, P Maisonneuve, SS Visweswariah Journal of Biological Chemistry 300 (1), 2024 | | 2024 |
structural Biology H Lavoie, M Sahmi, P Maisonneuve, SA Marullo, N Thevakumaran, T Jin Cell 172, 1022-37, 2018 | | 2018 |
Pleiotropic Role Played by the PDZ Domain in Neuronal Signaling Pathways C Caillet-Saguy, P Maisonneuve, F Delhommel, H Buc, M Lafon, ... Biophysical Journal 110 (3), 362a, 2016 | | 2016 |