| Pyrrolodiazines. 2. Structure and Chemistry of Pyrrolo[1,2-a]pyrazine and 1,3-Dipolar Cycloaddition of Its Azomethine Ylides JM Mínguez, MI Castellote, JJ Vaquero, JL García-Navio, J Alvarez-Builla, ... The Journal of Organic Chemistry 61 (14), 4655-4665, 1996 | 44 | 1996 |
| Cyclopropyl carboxamides: a new oral antimalarial series derived from the Tres Cantos anti-malarial set (TCAMS) L Rueda, I Castellote, J Castro-Pichel, MJ Chaparro, JC de la Rosa, ... ACS Medicinal Chemistry Letters 2 (11), 840-844, 2011 | 38 | 2011 |
| Reaction of imines with N-iodosuccinimide (NIS): unexpected formation of stable 1: 1 complexes I Castellote, M Morón, C Burgos, J Alvarez-Builla, A Martin, P Gómez-Sal, ... Chemical communications, 1281-1283, 2007 | 29 | 2007 |
| Pyrrolodiazines. 6. Palladium-Catalyzed Arylation, Heteroarylation, and Amination of 3,4-Dihydropyrrolo[1,2-a]pyrazines I Castellote, JJ Vaquero, J Fernández-Gadea, J Alvarez-Builla The Journal of Organic Chemistry 69 (25), 8668-8675, 2004 | 23 | 2004 |
| Palladium-catalysed amination of 2-acyl-1-alkyl-5-bromopyrroles I Castellote, JJ Vaquero, J Alvarez-Builla Tetrahedron letters 45 (4), 769-772, 2004 | 21 | 2004 |
| The domino chemistry approach to molecular complexity: high-yielding bis-hetero intramolecular Diels–Alder reactions with ketone components A Chanu, I Castellote, A Commeureuc, I Safir, S Arseniyadis Tetrahedron: Asymmetry 17 (17), 2565-2591, 2006 | 19 | 2006 |
| Palladium-catalyzed arylation and heteroarylation of azolopyrimidines J Mendiola, I Castellote, J Alvarez-Builla, J Fernández-Gadea, A Gómez, ... The Journal of Organic Chemistry 71 (3), 1254-1257, 2006 | 19 | 2006 |
| The domino chemistry approach to molecular complexity: Competing domino processes modulated by the substitution pattern I Safir, I Castellote, S Porcel, T Kaoudi, N Birlirakis, L Toupet, ... Chemistry–A European Journal 12 (28), 7337-7344, 2006 | 13 | 2006 |
| Microwave-accelerated competing domino processes: A tether-controlled dual pathway into high molecular complexity Z Elkhayat, I Safir, I Castellote, P Retailleau, S Arseniyadis Organic Letters 10 (11), 2219-2222, 2008 | 12 | 2008 |
| Pyrrolodiazines. Part 4. Structure and Chemistry of 3, 4‐Dihydropyrrolo (1, 2‐a) pyrazine. JM Minguez, I Castellote, JJ Vaquero, JL Garcia Navio, J Alavarez‐Builla, ... ChemInform 28 (48), 1997 | 12* | 1997 |
| High-content phenotypic screen of a focused TCAMS drug library identifies novel disruptors of the malaria parasite calcium dynamics W Chia, MG Gomez-Lorenzo, I Castellote, JX Tong, ... ACS Chemical Biology 16 (11), 2348-2372, 2021 | 4 | 2021 |
| A decade of malaria phenotypic screenings: Key lessons on the discovery and development of new antimalarial drugs E Fernández, MI Castellote, MJ Chaparro, B Díaz, J Fernández, M Gordo, ... Annual reports in medicinal chemistry 53, 1-23, 2019 | 4 | 2019 |
| Facile access to 1, 4-disubstituted pyrrolo [1, 2-a] pyrazines from α-aminoacetonitriles A Karmakar, S Ramalingam, M Basha, GK Indasi, M Belema, ... Synthesis 52 (03), 441-449, 2020 | 3 | 2020 |
| Baeyer–Villiger Oxidation of the Bicyclo [2.2. 2] octanone System Revisited: Searching for a Modular Construction of Heavily Substituted Cyclohexanes Based on m‐CPBA Mediated … L Finet, M Dakir, I Castellote, S Arseniyadis European journal of organic chemistry 2007 (24), 4116-4123, 2007 | 3 | 2007 |
| Discovery of pyrrolidinamides, a novel chemical class for malaria treatment: First time disclosure of the orally bioavailable clinical candidate GSK701 W Rami, I Castellote, FJ Gamo, J Haselden, FC Romo ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018 | 2 | 2018 |
| DISCOVERY OF GSK701, A NOVEL ORALLY EFFECTIVE PRECLINICAL DRUG CANDIDATE FOR THE TREATMENT OF MALARIA M Castellote Alvaro American Journal of Tropical Medicine and Hygiene 99 (4), 95-96, 2018 | 1 | 2018 |
| Novel inhibitors that target bacterial virulence identified via HTS against intra-macrophage survival of Shigella flexneri M Miljkovic, S Lozano, I Castellote, C de Cózar, AI Villegas-Moreno, ... Msphere 8 (5), e00154-23, 2023 | | 2023 |
| ANTIMALARIAL PYRROLIDINAMIDES FAST-ACTING COMPOUNDS WITH A NOVEL MODE OF ACTION L Sanz, M Gomez, M Jose Lafuente, I Castellote, J Haselden, ... AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 99 (4), 232-232, 2018 | | 2018 |
| NEW ANTIMALARIAL FAMILY" RESISTANT TO RESISTANCE" DEVELOPMENT LM Sanz, I Castellote, C de Cozar, B Crespo, M Jesus Almela, V Franco, ... AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 95 (5), 82-82, 2017 | | 2017 |
| Pyrazine compounds for use in the treatment of parasitic protozoal infections MI Castellote, M Garcia WO Patent WO 2017/067881 A1, 2017 | | 2017 |
