| Structure-based discovery of opioid analgesics with reduced side effects A Manglik, H Lin, DK Aryal, JD McCorvy, D Dengler, G Corder, A Levit, ... Nature 537 (7619), 185-190, 2016 | 986 | 2016 |
| Design of an in vitro biocatalytic cascade for the manufacture of islatravir MA Huffman, A Fryszkowska, O Alvizo, M Borra-Garske, KR Campos, ... Science 366 (6470), 1255-1259, 2019 | 466 | 2019 |
| An aggregation advisor for ligand discovery JJ Irwin, D Duan, H Torosyan, AK Doak, KT Ziebart, T Sterling, ... Journal of medicinal chemistry 58 (17), 7076-7087, 2015 | 422 | 2015 |
| Colloidal Aggregation and the in Vitro Activity of Traditional Chinese Medicines D Duan, AK Doak, L Nedyalkova, BK Shoichet ACS chemical biology 10 (4), 978-988, 2015 | 74 | 2015 |
| A kinase-cGAS cascade to synthesize a therapeutic STING activator JA McIntosh, Z Liu, BM Andresen, NS Marzijarani, JC Moore, NM Marshall, ... Nature 603 (7901), 439-444, 2022 | 71 | 2022 |
| Stable colloidal drug aggregates catch and release active enzymes CK McLaughlin, D Duan, AN Ganesh, H Torosyan, BK Shoichet, ... ACS chemical biology 11 (4), 992-1000, 2016 | 48 | 2016 |
| Internal structure and preferential protein binding of colloidal aggregates D Duan, H Torosyan, D Elnatan, CK McLaughlin, J Logie, MS Shoichet, ... ACS chemical biology 12 (1), 282-290, 2017 | 33 | 2017 |
| A new spin on antibody–drug conjugates: Trastuzumab-fulvestrant colloidal drug aggregates target HER2-positive cells AN Ganesh, CK McLaughlin, D Duan, BK Shoichet, MS Shoichet ACS applied materials & interfaces 9 (14), 12195-12202, 2017 | 28 | 2017 |
| A chemoenzymatic strategy for site-selective functionalization of native peptides and proteins A Fryszkowska, C An, O Alvizo, G Banerjee, KA Canada, Y Cao, ... Science 376 (6599), 1321-1327, 2022 | 26 | 2022 |
| Diverse modes of galacto-specific carbohydrate recognition by a family 31 glycoside hydrolase from Clostridium perfringens JM Grondin, D Duan, AC Kirlin, KT Abe, S Chitayat, HL Spencer, ... PLoS One 12 (2), e0171606, 2017 | 21 | 2017 |
| Neck rotation and neck mimic docking in the noncatalytic Kar3-associated protein Vik1 D Duan, Z Jia, M Joshi, J Brunton, M Chan, D Drew, D Davis, ... Journal of Biological Chemistry 287 (48), 40292-40301, 2012 | 18 | 2012 |
| Canada, KA; Bulger, PG; Sherry, BD; Truppo, M. D.; Ruck, RT; Campeau, L.-C.; Bennett, DJ; Humphrey, GR; Campos, KR; Maddess, ML A Kinase-cGAS Cascade to Synthesize a … JA McIntosh, Z Liu, BM Andresen, NS Marzijarani, JC Moore, NM Marshall, ... Nature 603 (7901), 439-444, 2022 | 15 | 2022 |
| Crystal structure of the Kar3‐like kinesin motor domain from the filamentous fungus Ashbya gossypii D Duan, DJ Hnatchuk, J Brenner, D Davis, JS Allingham Proteins: Structure, Function, and Bioinformatics 80 (4), 1016-1027, 2012 | 14 | 2012 |
| Structure-based approach for identification of novel phenylboronic acids as serine-β-lactamase inhibitors J Sgrignani, F De Luca, H Torosyan, JD Docquier, D Duan, B Novati, ... Journal of computer-aided molecular design 30, 851-861, 2016 | 13 | 2016 |
| KA Canada, PG Bulger, BD Sherry, MD Truppo, RT Ruck, LC Campeau, DJ Bennett, GR Humphrey, KR Campos, ML Maddess JA McIntosh, Z Liu, BM Andresen, NS Marzijarani, JC Moore, NM Marshall, ... Nature 603, 439-444, 2022 | 11 | 2022 |
| Engineered deoxyribose-phosphate aldolases D Duan, O Alvizo, J Nazor, HC Maniar, JN Riggins, J Vroom, ... US Patent 11,274,286, 2022 | 5 | 2022 |
| Ketoreductase polypeptides and polynucleotides JC Moore, J Liang, J Penfield, J Nazor, N Dellas, V Mitchell, D Duan, ... US Patent 11,021,729, 2021 | 5 | 2021 |
| Kar3Vik1 mechanochemistry is inhibited by mutation or deletion of the C terminus of the Vik1 subunit M Joshi, D Duan, D Drew, Z Jia, D Davis, RL Campbell, JS Allingham Journal of Biological Chemistry 288 (52), 36957-36970, 2013 | 5 | 2013 |
| Engineered phosphopentomutase variant enzymes SJ Novick, X Yi, N Dellas, O Alvizo, J Nazor, D Duan, V Mitchell, J Vroom, ... US Patent 11,034,948, 2021 | 4 | 2021 |
| Engineered adenylate kinase variant enzymes D Duan, AA Sowell-Kantz, AL Petkova, O Alvizo US Patent 11,913,037, 2024 | 2 | 2024 |
