| Hematopoiesis: an evolving paradigm for stem cell biology SH Orkin, LI Zon Cell 132 (4), 631-644, 2008 | 3211 | 2008 |
| Epigenetic memory in induced pluripotent stem cells K Kim, A Doi, B Wen, K Ng, R Zhao, P Cahan, J Kim, MJ Aryee, H Ji, ... Nature 467 (7313), 285-290, 2010 | 2640 | 2010 |
| A comparative encyclopedia of DNA elements in the mouse genome F Yue, Y Cheng, A Breschi, J Vierstra, W Wu, T Ryba, R Sandstrom, Z Ma, ... Nature 515 (7527), 355-364, 2014 | 1928 | 2014 |
| An early haematopoietic defect in mice lacking the transcription factor GATA-2 FY Tsai, G Keller, FC Kuo, M Weiss, J Chen, M Rosenblatt, FW Alt, ... Nature 371 (6494), 221-226, 1994 | 1770 | 1994 |
| Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping M Gessler, A Poustka, W Cavenee, RL Neve, SH Orkin, GAP Bruns Nature 343 (6260), 774-778, 1990 | 1643 | 1990 |
| Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1 L Pevny, MC Simon, E Robertson, WH Klein, SF Tsai, V D'Agati, SH Orkin, ... Nature 349 (6306), 257-260, 1991 | 1626 | 1991 |
| Mapping the mouse cell atlas by microwell-seq X Han, R Wang, Y Zhou, L Fei, H Sun, S Lai, A Saadatpour, Z Zhou, ... Cell 172 (5), 1091-1107. e17, 2018 | 1571 | 2018 |
| An extended transcriptional network for pluripotency of embryonic stem cells J Kim, J Chu, X Shen, J Wang, SH Orkin Cell 132 (6), 1049-1061, 2008 | 1569 | 2008 |
| A protein interaction network for pluripotency of embryonic stem cells J Wang, S Rao, J Chu, X Shen, DN Levasseur, TW Theunissen, SH Orkin Nature 444 (7117), 364-368, 2006 | 1328 | 2006 |
| Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis TE North, W Goessling, CR Walkley, C Lengerke, KR Kopani, AM Lord, ... Nature 447 (7147), 1007-1011, 2007 | 1269 | 2007 |
| Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL RA Shivdasani, EL Mayer, SH Orkin Nature 373 (6513), 432-434, 1995 | 1177 | 1995 |
| Linkage of β-thalassaemia mutations and β-globin gene polymorphisms with DNA polymorphisms in human β-globin gene cluster SH Orkin, HH Kazazian Jr, SE Antonarakis, SC Goff, CD Boehm, ... Nature 296 (5858), 627-631, 1982 | 1137 | 1982 |
| GATA-binding transcription factors in hematopoietic cells SH Orkin Blood 80 (3), 575-581, 1992 | 1135 | 1992 |
| A critical role for eosinophils in allergic airways remodeling AA Humbles, CM Lloyd, SJ McMillan, DS Friend, G Xanthou, EE McKenna, ... Science 305 (5691), 1776-1779, 2004 | 1101 | 2004 |
| EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency X Shen, Y Liu, YJ Hsu, Y Fujiwara, J Kim, X Mao, GC Yuan, SH Orkin Molecular cell 32 (4), 491-502, 2008 | 1094 | 2008 |
| Toward improving Caenorhabditis elegans phenome mapping with an ORFeome-based RNAi library JF Rual, J Ceron, J Koreth, T Hao, AS Nicot, T Hirozane-Kishikawa, ... Genome research 14 (10b), 2162-2168, 2004 | 1083 | 2004 |
| Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells SF Tsai, DIK Martin, LI Zon, AD D'Andrea, GG Wong, SH Orkin Nature 339 (6224), 446-451, 1989 | 1064 | 1989 |
| Cloning the gene for an inherited human disorder—chronic granulomatous disease—on the basis of its chromosomal location B Royer-Pokora, LM Kunkel, AP Monaco, SC Goff, PE Newburger, ... Nature 322 (6074), 32-38, 1986 | 1060 | 1986 |
| Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A VG Sankaran, TF Menne, J Xu, TE Akie, G Lettre, B Van Handel, ... Science 322 (5909), 1839-1842, 2008 | 1037 | 2008 |
| Mouse model of X–linked chronic granulomatous disease, an inherited defect in phagocyte superoxide production JD Pollock, DA Williams, MAC Gifford, LL Li, X Du, J Fisherman, SH Orkin, ... Nature genetics 9 (2), 202-209, 1995 | 1024 | 1995 |
