| Some gating potentiators, including VX-770, diminish ΔF508-CFTR functional expression G Veit, RG Avramescu, D Perdomo, PW Phuan, M Bagdany, PM Apaja, ... Science translational medicine 6 (246), 246ra97-246ra97, 2014 | 333 | 2014 |
| Identification and structural characterization of the neuronal luteinizing hormone receptor associated with sensory systems PM Apaja, KT Harju, JT Aatsinki, UE Petäjä-Repo, HJ Rajaniemi Journal of Biological Chemistry 279 (3), 1899-1906, 2004 | 99 | 2004 |
| Protein quality control at the plasma membrane T Okiyoneda, PM Apaja, GL Lukacs Current opinion in cell biology 23 (4), 483-491, 2011 | 89 | 2011 |
| Inefficient maturation of the rat luteinizing hormone receptor: a putative way to regulate receptor numbers at the cell surface EM Pietilä, JT Tuusa, PM Apaja, JT Aatsinki, AE Hakalahti, ... Journal of Biological Chemistry 280 (28), 26622-26629, 2005 | 83 | 2005 |
| Chaperone-independent peripheral quality control of CFTR by RFFL E3 ligase T Okiyoneda, G Veit, R Sakai, M Aki, T Fujihara, M Higashi, ... Developmental cell 44 (6), 694-708. e7, 2018 | 76 | 2018 |
| Quality control for unfolded proteins at the plasma membrane PM Apaja, H Xu, GL Lukacs The Journal of Cell Biology 191 (3), 553, 2010 | 75 | 2010 |
| Chaperones rescue the energetic landscape of mutant CFTR at single molecule and in cell M Bagdany, G Veit, R Fukuda, RG Avramescu, T Okiyoneda, I Baaklini, ... Nature communications 8 (1), 398, 2017 | 71 | 2017 |
| Interplay of endosomal pH and ligand occupancy in integrin α5β1 ubiquitination, endocytic sorting, and cell migration D Kharitidi, PM Apaja, S Manteghi, K Suzuki, E Malitskaya, A Roldan, ... Cell reports 13 (3), 599-609, 2015 | 67 | 2015 |
| Insights into MLC pathogenesis: GlialCAM is an MLC1 chaperone required for proper activation of volume-regulated anion currents X Capdevila-Nortes, T Lopez-Hernandez, PM Apaja, M López de Heredia, ... Human molecular genetics 22 (21), 4405-4416, 2013 | 63 | 2013 |
| Ribosomal stalk protein silencing partially corrects the ΔF508-CFTR functional expression defect G Veit, K Oliver, PM Apaja, D Perdomo, A Bidaud-Meynard, ST Lin, J Guo, ... PLoS biology 14 (5), e1002462, 2016 | 60 | 2016 |
| Luteinizing hormone receptor ectodomain splice variant misroutes the full-length receptor into a subcompartment of the endoplasmic reticulum PM Apaja, JT Tuusa, EM Pietilä, HJ Rajaniemi, UE Petäjä-Repo Molecular biology of the cell 17 (5), 2243-2255, 2006 | 59 | 2006 |
| Ubiquitination-dependent quality control of hERG K+ channel with acquired and inherited conformational defect at the plasma membrane PM Apaja, B Foo, T Okiyoneda, WC Valinsky, H Barriere, R Atanasiu, ... Molecular biology of the cell 24 (24), 3787-3804, 2013 | 56 | 2013 |
| Protein homeostasis at the plasma membrane PM Apaja, GL Lukacs Physiology 29 (4), 265-277, 2014 | 49 | 2014 |
| Expression of the mature luteinizing hormone receptor in rodent urogenital and adrenal tissues is developmentally regulated at a posttranslational level PM Apaja, JT Aatsinki, HJ Rajaniemi, UE Petäjä-Repo Endocrinology 146 (8), 3224-3232, 2005 | 47 | 2005 |
| Leukoencephalopathy‐causing CLCN2 mutations are associated with impaired Cl− channel function and trafficking H Gaitán‐Peñas, PM Apaja, T Arnedo, A Castellanos, X Elorza‐Vidal, ... The Journal of Physiology 595 (22), 6993-7008, 2017 | 29 | 2017 |
| The endoplasmic reticulum Ca2+-pump SERCA2b interacts with G protein-coupled receptors and enhances their expression at the cell surface JT Tuusa, PMH Markkanen, PM Apaja, AE Hakalahti, UE Petäjä-Repo Journal of molecular biology 371 (3), 622-638, 2007 | 29 | 2007 |
| A novel fluorescent probe reveals starvation controls the commitment of amyloid precursor protein to the lysosome LK Hein, PM Apaja, K Hattersley, RH Grose, J Xie, CG Proud, TJ Sargeant Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1864 (10), 1554-1565, 2017 | 21 | 2017 |
| Degradation mechanism of a Golgi-retained distal renal tubular acidosis mutant of the kidney anion exchanger 1 in renal cells CY Chu, J King, M Berrini, AC Rumley, PM Apaja, GL Lukacs, ... American Journal of Physiology-Cell Physiology 307 (3), C296-C307, 2014 | 17 | 2014 |
| Endocytic sorting of CFTR variants monitored by single-cell fluorescence ratiometric image analysis (FRIA) in living cells H Barrière, P Apaja, T Okiyoneda, GL Lukacs Cystic Fibrosis: Diagnosis and Protocols, Volume I: Approaches to Study and …, 2011 | 14 | 2011 |
| Ubr1-induced selective endophagy/autophagy protects against the endosomal and Ca2+-induced proteostasis disease stress BB Wang, H Xu, S Isenmann, C Huang, X Elorza-Vidal, GY Rychkov, ... Cellular and Molecular Life Sciences 79 (3), 167, 2022 | 8 | 2022 |
