p21 is a universal inhibitor of cyclin kinases Y Xiong, GJ Hannon, H Zhang, D Casso, R Kobayashi, D Beach Nature 366 (6456), 701-704, 1993 | 4576 | 1993 |
Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases W Xu, H Yang, Y Liu, Y Yang, P Wang, SH Kim, S Ito, C Yang, P Wang, ... Cancer cell 19 (1), 17-30, 2011 | 3070 | 2011 |
ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways Y Zhang, Y Xiong, WG Yarbrough Cell 92 (6), 725-734, 1998 | 2173 | 1998 |
Regulation of cellular metabolism by protein lysine acetylation S Zhao, W Xu, W Jiang, W Yu, Y Lin, T Zhang, J Yao, L Zhou, Y Zeng, H Li, ... Science 327 (5968), 1000-1004, 2010 | 2080 | 2010 |
Origin and evolution of retroelements based upon their reverse transcriptase sequences. Y Xiong, TH Eickbush The EMBO journal 9 (10), 3353-3362, 1990 | 1709 | 1990 |
Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1α S Zhao, Y Lin, W Xu, W Jiang, Z Zha, P Wang, W Yu, Z Li, L Gong, Y Peng, ... Science 324 (5924), 261-265, 2009 | 1395 | 2009 |
D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA Y Xiong, H Zhang, D Beach Cell 71 (3), 505-514, 1992 | 1381 | 1992 |
Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters T Hung, Y Wang, MF Lin, AK Koegel, Y Kotake, GD Grant, HM Horlings, ... Nature genetics 43 (7), 621-629, 2011 | 1363 | 2011 |
Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts DA Alcorta, Y Xiong, D Phelps, G Hannon, D Beach, JC Barrett Proceedings of the National Academy of Sciences 93 (24), 13742-13747, 1996 | 1334 | 1996 |
Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism. MB Datto, Y Li, JF Panus, DJ Howe, Y Xiong, XF Wang Proceedings of the National Academy of Sciences 92 (12), 5545-5549, 1995 | 1231 | 1995 |
Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15INK4B tumor suppressor gene Y Kotake, T Nakagawa, K Kitagawa, S Suzuki, N Liu, M Kitagawa, Y Xiong Oncogene 30 (16), 1956-1962, 2011 | 1191 | 2011 |
Acetylation of metabolic enzymes coordinates carbon source utilization and metabolic flux Q Wang, Y Zhang, C Yang, H Xiong, Y Lin, J Yao, H Li, L Xie, W Zhao, ... Science 327 (5968), 1004-1007, 2010 | 1124 | 2010 |
Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors M Xiao, H Yang, W Xu, S Ma, H Lin, H Zhu, L Liu, Y Liu, C Yang, Y Xu, ... Genes & development 26 (12), 1326-1338, 2012 | 1119 | 2012 |
Growth suppression by p18, a p16INK4/MTS1-and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function. KL Guan, CW Jenkins, Y Li, MA Nichols, X Wu, CL O'Keefe, AG Matera, ... Genes & development 8 (24), 2939-2952, 1994 | 1054 | 1994 |
TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway QY Lei, H Zhang, B Zhao, ZY Zha, F Bai, XH Pei, S Zhao, Y Xiong, ... Molecular and cellular biology 28 (7), 2426-2436, 2008 | 1035 | 2008 |
Human D-type cyclin Y Xiong, T Connolly, B Futcher, D Beach Cell 65 (4), 691-699, 1991 | 970 | 1991 |
BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase M Furukawa, Y Xiong Molecular and cellular biology 25 (1), 162-171, 2005 | 855 | 2005 |
Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation. Y Xiong, H Zhang, D Beach Genes & development 7 (8), 1572-1583, 1993 | 762 | 1993 |
Ribosomal protein L11 negatively regulates oncoprotein MDM2 and mediates a p53-dependent ribosomal-stress checkpoint pathway Y Zhang, GW Wolf, K Bhat, A Jin, T Allio, WA Burkhart, Y Xiong Molecular and cellular biology 23 (23), 8902-8912, 2003 | 654 | 2003 |
Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation H Yang, Y Liu, F Bai, JY Zhang, SH Ma, J Liu, ZD Xu, HG Zhu, ZQ Ling, ... Oncogene 32 (5), 663-669, 2013 | 650 | 2013 |