Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells ES Lippmann, SM Azarin, JE Kay, RA Nessler, HK Wilson, A Al-Ahmad, ... Nature biotechnology 30 (8), 783-791, 2012 | 809 | 2012 |
A retinoic acid-enhanced, multicellular human blood-brain barrier model derived from stem cell sources ES Lippmann, A Al-Ahmad, SM Azarin, SP Palecek, EV Shusta Scientific reports 4 (1), 4160, 2014 | 505 | 2014 |
A 3D culture model of innervated human skeletal muscle enables studies of the adult neuromuscular junction M Afshar Bakooshli, ES Lippmann, B Mulcahy, N Iyer, CT Nguyen, K Tung, ... Elife 8, e44530, 2019 | 221 | 2019 |
Deterministic HOX patterning in human pluripotent stem cell-derived neuroectoderm ES Lippmann, CE Williams, DA Ruhl, MC Estevez-Silva, ER Chapman, ... Stem cell reports 4 (4), 632-644, 2015 | 198 | 2015 |
Accelerated differentiation of human induced pluripotent stem cells to blood–brain barrier endothelial cells EK Hollmann, AK Bailey, AV Potharazu, MD Neely, AB Bowman, ... Fluids and Barriers of the CNS 14, 1-13, 2017 | 195 | 2017 |
A simplified, fully defined differentiation scheme for producing blood-brain barrier endothelial cells from human iPSCs EH Neal, NA Marinelli, Y Shi, PM McClatchey, KM Balotin, DR Gullett, ... Stem cell reports 12 (6), 1380-1388, 2019 | 175 | 2019 |
Evidence for a two-step mechanism in electronically selective single-walled carbon nanotube reactions ML Usrey, ES Lippmann, MS Strano Journal of the American Chemical Society 127 (46), 16129-16135, 2005 | 175 | 2005 |
Modeling the blood–brain barrier using stem cell sources ES Lippmann, A Al-Ahmad, SP Palecek, EV Shusta Fluids and Barriers of the CNS 10, 1-14, 2013 | 141 | 2013 |
Defined human pluripotent stem cell culture enables highly efficient neuroepithelium derivation without small molecule inhibitors ES Lippmann, MC Estevez-Silva, RS Ashton Stem Cells 32 (4), 1032-1042, 2014 | 140 | 2014 |
Blood–brain barrier modeling with co‐cultured neural progenitor cell‐derived astrocytes and neurons ES Lippmann, C Weidenfeller, CN Svendsen, EV Shusta Journal of neurochemistry 119 (3), 507-520, 2011 | 103 | 2011 |
iPSC-derived brain endothelium exhibits stable, long-term barrier function in perfused hydrogel scaffolds SL Faley, EH Neal, JX Wang, AM Bosworth, CM Weber, KM Balotin, ... Stem Cell Reports 12 (3), 474-487, 2019 | 95 | 2019 |
Endothelial cells are critical regulators of iron transport in a model of the human blood–brain barrier B Chiou, EH Neal, AB Bowman, ES Lippmann, IA Simpson, JR Connor Journal of Cerebral Blood Flow & Metabolism 39 (11), 2117-2131, 2019 | 94 | 2019 |
Commentary on human pluripotent stem cell-based blood–brain barrier models ES Lippmann, SM Azarin, SP Palecek, EV Shusta Fluids and Barriers of the CNS 17, 1-6, 2020 | 82 | 2020 |
CRISPRi screens in human iPSC-derived astrocytes elucidate regulators of distinct inflammatory reactive states K Leng, IVL Rose, H Kim, W Xia, W Romero-Fernandez, B Rooney, ... Nature neuroscience 25 (11), 1528-1542, 2022 | 76 | 2022 |
Reactive astrocytes transduce inflammation in a blood-brain barrier model through a TNF-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin H Kim, K Leng, J Park, AG Sorets, S Kim, A Shostak, RJ Embalabala, ... Nature communications 13 (1), 6581, 2022 | 70 | 2022 |
Diagnosis of immunomarkers in vivo via multiplexed surface enhanced Raman spectroscopy with gold nanostars YC Ou, JA Webb, CM O'Brien, IJ Pence, EC Lin, EP Paul, D Cole, SH Ou, ... Nanoscale 10 (27), 13092-13105, 2018 | 59 | 2018 |
Identification and expression profiling of blood–brain barrier membrane proteins N Agarwal, ES Lippmann, EV Shusta Journal of neurochemistry 112 (3), 625-635, 2010 | 53 | 2010 |
Activation of RARα, RARγ, or RXRα increases barrier tightness in human induced pluripotent stem cell‐derived brain endothelial cells MJ Stebbins, ES Lippmann, MG Faubion, R Daneman, SP Palecek, ... Biotechnology Journal 13 (2), 1700093, 2018 | 51 | 2018 |
Sequential nucleophilic substitutions permit orthogonal click functionalization of multicomponent PEG brushes J Sha, ES Lippmann, J McNulty, Y Ma, RS Ashton Biomacromolecules 14 (9), 3294-3303, 2013 | 46 | 2013 |
Advances in blood–brain barrier modeling in microphysiological systems highlight critical differences in opioid transport due to cortisol exposure JA Brown, SL Faley, Y Shi, KM Hillgren, GA Sawada, TK Baker, ... Fluids and Barriers of the CNS 17, 1-12, 2020 | 35 | 2020 |