Inhibition of mammalian target of rapamycin or apoptotic pathway induces autophagy and radiosensitizes PTEN null prostate cancer cells C Cao, T Subhawong, JM Albert, KW Kim, L Geng, KR Sekhar, YJ Gi, B Lu Cancer research 66 (20), 10040-10047, 2006 | 402 | 2006 |
Inhibition of poly (ADP-ribose) polymerase enhances cell death and improves tumor growth delay in irradiated lung cancer models JM Albert, C Cao, KW Kim, CD Willey, L Geng, D Xiao, H Wang, A Sandler, ... Clinical cancer research 13 (10), 3033-3042, 2007 | 333 | 2007 |
Targeting the mechanisms of resistance to chemotherapy and radiotherapy with the cancer stem cell hypothesis R Morrison, SM Schleicher, Y Sun, KJ Niermann, S Kim, DE Spratt, ... Journal of oncology 2011 (1), 941876, 2011 | 295 | 2011 |
Survivin as a therapeutic target for radiation sensitization in lung cancer B Lu, Y Mu, C Cao, F Zeng, S Schneider, J Tan, J Price, J Chen, ... Cancer research 64 (8), 2840-2845, 2004 | 247 | 2004 |
Autophagy for cancer therapy through inhibition of pro-apoptotic proteins and mammalian target of rapamycin signaling KW Kim, RW Mutter, C Cao, JM Albert, M Freeman, DE Hallahan, B Lu Journal of Biological Chemistry 281 (48), 36883-36890, 2006 | 227 | 2006 |
Targeting the Akt/mammalian target of rapamycin pathway for radiosensitization of breast cancer JM Albert, KW Kim, C Cao, B Lu Molecular cancer therapeutics 5 (5), 1183-1189, 2006 | 226 | 2006 |
Enhanced radiation damage of tumor vasculature by mTOR inhibitors ET Shinohara, C Cao, K Niermann, Y Mu, F Zeng, DE Hallahan, B Lu Oncogene 24 (35), 5414-5422, 2005 | 225 | 2005 |
XIAP and survivin as therapeutic targets for radiation sensitization in preclinical models of lung cancer C Cao, Y Mu, DE Hallahan, B Lu Oncogene 23 (42), 7047-7052, 2004 | 218 | 2004 |
Autophagy upregulation by inhibitors of caspase-3 and mTOR enhances radiotherapy in a mouse model of lung cancer KW Kim, M Hwang, L Moretti, JJ Jaboin, YI Cha, B Lu Autophagy 4 (5), 659-668, 2008 | 203 | 2008 |
Targeting brain metastases in ALK-rearranged non-small-cell lung cancer I Zhang, NG Zaorsky, JD Palmer, R Mehra, B Lu The lancet oncology 16 (13), e510-e521, 2015 | 196 | 2015 |
Switch between apoptosis and autophagy: radiation-induced endoplasmic reticulum stress? L Moretti, YI Cha, KJ Niermann, B Lu Cell cycle 6 (7), 793-798, 2007 | 189 | 2007 |
Integrin αvβ3 antagonist Cilengitide enhances efficacy of radiotherapy in endothelial cell and non–small-cell lung cancer models JM Albert, C Cao, L Geng, L Leavitt, DE Hallahan, B Lu International Journal of Radiation Oncology* Biology* Physics 65 (5), 1536-1543, 2006 | 160 | 2006 |
Autophagy signaling in cancer and its potential as novel target to improve anticancer therapy L Moretti, ES Yang, KW Kim, B Lu Drug Resistance Updates 10 (4-5), 135-143, 2007 | 159 | 2007 |
Endoplasmic reticulum stress mediates radiation-induced autophagy by perk-eIF2α in caspase-3/7-deficient cells KW Kim, L Moretti, LR Mitchell, DK Jung, B Lu Oncogene 29 (22), 3241-3251, 2010 | 148 | 2010 |
Nuclear survivin predicts recurrence and poor survival in patients with resected nonsmall cell lung carcinoma ET Shinohara, A Gonzalez, PP Massion, H Chen, M Li, AS Freyer, ... Cancer: Interdisciplinary International Journal of the American Cancer …, 2005 | 141 | 2005 |
Combined Bcl-2/Mammalian Target of Rapamycin Inhibition Leads to Enhanced Radiosensitization via Induction of Apoptosis and Autophagy in Non–Small Cell Lung Tumor Xenograft Model KW Kim, L Moretti, LR Mitchell, DK Jung, B Lu Clinical Cancer Research 15 (19), 6096-6105, 2009 | 134 | 2009 |
Progress in the unraveling of the endoplasmic reticulum stress/autophagy pathway and cancer: implications for future therapeutic approaches SM Schleicher, L Moretti, V Varki, B Lu Drug resistance updates 13 (3), 79-86, 2010 | 130 | 2010 |
Blockade of tumor-expressed PD-1 promotes lung cancer growth S Du, N McCall, K Park, Q Guan, P Fontina, A Ertel, T Zhan, AP Dicker, ... Oncoimmunology 7 (4), e1408747, 2018 | 129 | 2018 |
Regulated cell death pathways: new twists in modulation of BCL2 family function N Sasi, M Hwang, J Jaboin, I Csiki, B Lu Molecular cancer therapeutics 8 (6), 1421-1429, 2009 | 127 | 2009 |
Impact of inhomogeneity corrections on dose coverage in the treatment of lung cancer using stereotactic body radiation therapy GX Ding, DM Duggan, B Lu, DE Hallahan, A Cmelak, A Malcolm, ... Medical physics 34 (7), 2985-2994, 2007 | 119 | 2007 |