Cell entry of cell penetrating peptides: tales of tails wagging dogs AT Jones, EJ Sayers Journal of Controlled Release 161 (2), 582-591, 2012 | 293 | 2012 |
Cell-penetrating peptide sequence and modification dependent uptake and subcellular distribution of green florescent protein in different cell lines SG Patel, EJ Sayers, L He, R Narayan, TL Williams, EM Mills, ... Scientific Reports 9 (1), 6298, 2019 | 215 | 2019 |
Receptor crosslinking: a general method to trigger internalization and lysosomal targeting of therapeutic receptor: ligand complexes PR Moody, EJ Sayers, JP Magnusson, C Alexander, P Borri, P Watson, ... Molecular Therapy 23 (12), 1888-1898, 2015 | 113 | 2015 |
Fluorescence labelling of extracellular vesicles using a novel thiol-based strategy for quantitative analysis of cellular delivery and intracellular traffic HD Roberts-Dalton, A Cocks, JM Falcon-Perez, EJ Sayers, JP Webber, ... Nanoscale 9 (36), 13693-13706, 2017 | 102 | 2017 |
Endocytic profiling of cancer cell models reveals critical factors influencing LNP-mediated mRNA delivery and protein expression EJ Sayers, SE Peel, A Schantz, RM England, M Beano, SM Bates, ... Molecular Therapy 27 (11), 1950-1962, 2019 | 74 | 2019 |
Cyanine dye mediated mitochondrial targeting enhances the anti-cancer activity of small-molecule cargoes AR Nödling, EM Mills, X Li, D Cardella, EJ Sayers, SH Wu, AT Jones, ... Chemical Communications 56 (34), 4672-4675, 2020 | 44 | 2020 |
Distal phenylalanine modification for enhancing cellular delivery of fluorophores, proteins and quantum dots by cell penetrating peptides EJ Sayers, K Cleal, NG Eissa, P Watson, AT Jones Journal of Controlled Release 195, 55-62, 2014 | 42 | 2014 |
Contrasting roles for actin in the cellular uptake of cell penetrating peptide conjugates L He, EJ Sayers, P Watson, AT Jones Scientific reports 8 (1), 7318, 2018 | 37 | 2018 |
Cell-penetrating antimicrobial peptides-prospectives for targeting intracellular infections JS Bahnsen, H Franzyk, EJ Sayers, AT Jones, HM Nielsen Pharmaceutical Research 32 (5), 1546-1556, 2015 | 33 | 2015 |
Co-operative Membrane Disruption Between Cell-penetrating Peptide and Cargo: Implications for the Therapeutic Use of the Bcl-2 Converter Peptide D-NuBCP-9-r8 CL Watkins, EJ Sayers, C Allender, D Barrow, C Fegan, P Brennan, ... Molecular Therapy 19 (12), 2124-2132, 2011 | 31 | 2011 |
siRNA Inhibition of Endocytic Pathways to Characterize the Cellular Uptake Mechanisms of Folate-Functionalized Glycol Chitosan Nanogels P Pereira, SS Pedrosa, JM Wymant, E Sayers, A Correia, M Vilanova, ... Molecular pharmaceutics 12 (6), 1970-1979, 2015 | 25 | 2015 |
Highly luminescent metallacages featuring bispyridyl ligands functionalised with BODIPY for imaging in cancer cells B Woods, D Döllerer, B Aikman, MN Wenzel, EJ Sayers, FE Kühn, ... Journal of inorganic biochemistry 199, 110781, 2019 | 22 | 2019 |
Strategic Trastuzumab Mediated Crosslinking Driving Concomitant HER2 and HER3 Endocytosis and Degradation in Breast Cancer JM Wymant, EJ Sayers, D Muir, AT Jones Journal of Cancer 11 (11), 3288, 2020 | 19 | 2020 |
Switching of Macromolecular Ligand Display by Thermoresponsive Polymers Mediates Endocytosis of Multiconjugate Nanoparticles EJ Sayers, JP Magnusson, PR Moody, F Mastrotto, C Conte, C Brazzale, ... Bioconjugate chemistry 29 (4), 1030-1046, 2018 | 16 | 2018 |
Targeted delivery and endosomal cellular uptake of DARPin-siRNA bioconjugates: Influence of linker stability on gene silencing C Lorenzer, S Streußnig, E Tot, AM Winkler, H Merten, F Brandl, ... European Journal of Pharmaceutics and Biopharmaceutics 141, 37-50, 2019 | 15 | 2019 |
Anti-schistosomal activities of quinoxaline-containing compounds: From hit identification to lead optimisation G Padalino, N El-Sakkary, LJ Liu, C Liu, DSG Harte, RE Barnes, E Sayers, ... European Journal of Medicinal Chemistry 226, 113823, 2021 | 12 | 2021 |
Four-wave-mixing microscopy reveals non-colocalisation between gold nanoparticles and fluorophore conjugates inside cells N Giannakopoulou, JB Williams, PR Moody, EJ Sayers, JP Magnusson, ... Nanoscale 12 (7), 4622-4635, 2020 | 12 | 2020 |
Highly-fluorescent BODIPY-functionalised metallacages as drug delivery systems: synthesis, characterisation and cellular accumulation studies B Aikman, R Bonsignore, B Woods, D Doellerer, R Scotti, C Schmidt, ... Dalton Transactions 51 (19), 7476-7490, 2022 | 10 | 2022 |
EJP18 peptide derived from the juxtamembrane domain of epidermal growth factor receptor represents a novel membrane-active cell-penetrating peptide NG Eissa, EJ Sayers, D Birch, SG Patel, YH Tsai, HM Nielsen, AT Jones Biochemical Journal 477 (1), 45-60, 2020 | 8 | 2020 |
Influence of folate-targeted gold nanoparticles on subcellular localization and distribution into lysosomes R Daniele, C Brazzale, B Arpac, F Tognetti, C Pesce, A Malfanti, E Sayers, ... Pharmaceutics 15 (3), 864, 2023 | 6 | 2023 |