Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 10684 | 2021 |
The release and trans-synaptic transmission of Tau via exosomes Y Wang, V Balaji, S Kaniyappan, L Krüger, S Irsen, K Tepper, ... Molecular neurodegeneration 12, 1-25, 2017 | 634 | 2017 |
Stages and conformations of the Tau repeat domain during aggregation and its effect on neuronal toxicity S Kumar, K Tepper, S Kaniyappan, J Biernat, S Wegmann, ... Journal of biological chemistry 289 (29), 20318-20332, 2014 | 90 | 2014 |
Extracellular low-n oligomers of tau cause selective synaptotoxicity without affecting cell viability S Kaniyappan, RR Chandupatla, EM Mandelkow, E Mandelkow Alzheimer's & Dementia 13 (11), 1270-1291, 2017 | 83 | 2017 |
FRET-based Tau seeding assay does not represent prion-like templated assembly of Tau filaments S Kaniyappan, K Tepper, J Biernat, RR Chandupatla, S Hübschmann, ... Molecular Neurodegeneration 15 (1), 39, 2020 | 49 | 2020 |
A combinatorial native MS and LC-MS/MS approach reveals high intrinsic phosphorylation of human Tau but minimal levels of other key modifications F Drepper, J Biernat, S Kaniyappan, HE Meyer, EM Mandelkow, ... Journal of Biological Chemistry 295 (52), 18213-18225, 2020 | 42 | 2020 |
Molecular crowding and RNA synergize to promote phase separation, microtubule interaction, and seeding of Tau condensates J Hochmair, C Exner, M Franck, A Dominguez‐Baquero, L Diez, ... The EMBO Journal 41 (11), e108882, 2022 | 40 | 2022 |
C3G (RapGEF1), a regulator of actin dynamics promotes survival and myogenic differentiation of mouse mesenchymal cells. RV Sasi Kumar K, Ramadhas A, Nayak SC, Kaniyappan S, Dayma K Biochim Biophys Acta., 2015 | 38* | 2015 |
Pathological missorting of endogenous MAPT/Tau in neurons caused by failure of protein degradation systems V Balaji, S Kaniyappan, E Mandelkow, Y Wang, EM Mandelkow Autophagy 14 (12), 2139-2154, 2018 | 33 | 2018 |
Potent Tau aggregation inhibitor D‐peptides selected against Tau‐repeat 2 using mirror image phage display M Malhis, S Kaniyappan, I Aillaud, RR Chandupatla, LM Ramirez, ... ChemBioChem 22 (21), 3049-3059, 2021 | 22 | 2021 |
Novel antibody against low‐n oligomers of tau protein promotes clearance of tau in cells via lysosomes RR Chandupatla, A Flatley, R Feederle, EM Mandelkow, S Kaniyappan Alzheimer's & Dementia: Translational Research & Clinical Interventions 6 (1 …, 2020 | 21 | 2020 |
Suppressing tau aggregation and toxicity by an anti-aggregant tau fragment GJ Pir, B Choudhary, S Kaniyappan, RR Chandupatla, E Mandelkow, ... Molecular neurobiology 56, 3751-3767, 2019 | 17 | 2019 |
The plasma factor XIII heterotetrameric complex structure: unexpected unequal pairing within a symmetric complex S Singh, A Nazabal, S Kaniyappan, JL Pellequer, AS Wolberg, D Imhof, ... Biomolecules 9 (12), 765, 2019 | 16 | 2019 |
A novel D-amino acid peptide with therapeutic potential (ISAD1) inhibits aggregation of neurotoxic disease-relevant mutant Tau and prevents Tau toxicity in vitro I Aillaud, S Kaniyappan, RR Chandupatla, LM Ramirez, S Alkhashrom, ... Alzheimer's Research & Therapy 14 (1), 15, 2022 | 13 | 2022 |
Disruption of structural disulfides of coagulation FXIII-B subunit; functional implications for a rare bleeding disorder S Singh, MS Akhter, J Dodt, A Sharma, S Kaniyappan, H Yadegari, ... International Journal of Molecular Sciences 20 (8), 1956, 2019 | 8 | 2019 |
Spreading of tau protein does not depend on aggregation propensity S Rodrigues, M Anglada-Huguet, K Hochgräfe, S Kaniyappan, ... Journal of Molecular Neuroscience 73 (9), 693-712, 2023 | 4 | 2023 |
Purification and characterization of low-n tau oligomers S Kaniyappan, RR Chandupatla, E Mandelkow Amyloid Proteins: Methods and Protocols, 99-111, 2018 | 3 | 2018 |
Reversal of tau-dependent cognitive decay by blocking adenosine A1 receptors: comparison of transgenic mouse models with different levels of tauopathy M Anglada-Huguet, H Endepols, A Sydow, R Hilgers, B Neumaier, ... International journal of molecular sciences 24 (11), 9260, 2023 | 2 | 2023 |
Discovery of Orally Available and Brain Penetrant AEP Inhibitors D Krummenacher, W He, B Kuhn, C Schnider, A Beurier, V Brom, ... Journal of Medicinal Chemistry 66 (24), 17026-17043, 2023 | 1 | 2023 |
Pre-stress of actin cortices is important for the viscoelastic response of living cells A Cordes, H Witt, A Gallemí-Pérez, B Brückner, F Grimm, M Vache, ... BioRxiv, 783613, 2019 | 1 | 2019 |