Structure and mechanism of an active lipid-linked oligosaccharide flippase C Perez, S Gerber, J Boilevin, M Bucher, T Darbre, M Aebi, JL Reymond, ... Nature, 2015 | 222 | 2015 |
Alternating-access mechanism in conformationally asymmetric trimers of the betaine transporter BetP. C Perez, C Koshy, O Yildiz, C Ziegler Nature, 2012 | 154 | 2012 |
Investigation of the sodium-binding sites in the sodium-coupled betaine transporter BetP K Khafizov, C Perez, C Koshy, M Quick, K Fendler, C Ziegler, LR Forrest Proceedings of the National Academy of Sciences 109 (44), E3035-E3044, 2012 | 90 | 2012 |
Structural basis of NINJ1-mediated plasma membrane rupture in cell death M Degen, JC Santos, K Pluhackova, G Cebrero, S Ramos, G Jankevicius, ... Nature 618 (7967), 1065-1071, 2023 | 80 | 2023 |
Structural evidence for functional lipid interactions in the betaine transporter BetP C Koshy, ES Schweikhard, RM Gärtner, C Perez, Ö Yildiz, C Ziegler The EMBO journal 32 (23), 3096-3105, 2013 | 70 | 2013 |
Substrate specificity and ion coupling in the Na+/betaine symporter BetP C Perez, C Koshy, S Ressl, S Nicklisch, R Krämer, C Ziegler The EMBO Journal 30 (7), 1221-1229, 2011 | 68 | 2011 |
Substrate-bound outward-open state of the betaine transporter BetP provides insights into Na+ coupling C Perez, B Faust, AR Mehdipour, KA Francesconi, LR Forrest, C Ziegler Nature Communications 5 (1), 4231, 2014 | 64 | 2014 |
The role of trimerization in the osmoregulated betaine transporter BetP C Perez, K Khafizov, LR Forrest, R Krämer, C Ziegler EMBO reports 12 (8), 804-810, 2011 | 54 | 2011 |
Locating an extracellular K+-dependent interaction site that modulates betaine-binding of the Na+-coupled betaine symporter BetP L Ge, C Perez, I Waclawska, C Ziegler, DJ Muller Proceedings of the National Academy of Sciences 108 (43), E890-E898, 2011 | 41 | 2011 |
Mechanistic aspects of sodium-binding sites in LeuT-like fold symporters C Perez, C Ziegler Biological chemistry 394 (5), 641-648, 2013 | 35 | 2013 |
Structure of outward-facing PglK and molecular dynamics of lipid-linked oligosaccharide recognition and translocation C Perez, AR Mehdipour, G Hummer, KP Locher Structure 27 (4), 669-678. e5, 2019 | 32 | 2019 |
Structure of a proton-dependent lipid transporter involved in lipoteichoic acids biosynthesis B Zhang, X Liu, E Lambert, G Mas, S Hiller, JW Veening, C Perez Nature structural & molecular biology 27 (6), 561-569, 2020 | 31 | 2020 |
Structural basis of inhibition of lipid-linked oligosaccharide flippase PglK by a conformational nanobody C Perez, M Köhler, D Janser, E Pardon, J Steyaert, R Zenobi, KP Locher Scientific Reports 7, 46641, 2017 | 31 | 2017 |
Binding specificities of nanobody• membrane protein complexes obtained from chemical cross-linking and high-mass maldi mass spectrometry M Köhler, C Neff, C Perez, C Brunner, E Pardon, J Steyaert, ... Analytical chemistry 90 (8), 5306-5313, 2018 | 20 | 2018 |
Role of bundle helices in a regulatory crosstalk in the trimeric betaine transporter BetP RM Gärtner, C Perez, C Koshy, C Ziegler Journal of molecular biology 414 (3), 327-336, 2011 | 20 | 2011 |
Mechanistic basis of choline import involved in teichoic acids and lipopolysaccharide modification N Bärland, AS Rueff, G Cebrero, CAJ Hutter, MA Seeger, JW Veening, ... Science Advances 8 (9), eabm1122, 2022 | 15 | 2022 |
Evidence for a trap-and-flip mechanism in a proton-dependent lipid transporter E Lambert, AR Mehdipour, A Schmidt, G Hummer, C Perez Nature Communications 13 (1), 1022, 2022 | 15 | 2022 |
Competence remodels the pneumococcal cell wall exposing key surface virulence factors that mediate increased host adherence V Minhas, A Domenech, D Synefiaridou, D Straume, M Brendel, ... PLoS Biology 21 (1), e3001990, 2023 | 11 | 2023 |
Expression, Purification, and Structural Biology of Membrane Proteins C Perez, T Maier | 7 | 2020 |
Osmotic stress response in BetP: How lipids and K+ team up to overcome downregulation V Heinz, G Güler, V Leone, MG Madej, S Maksimov, RM Gärtner, O Rudi, ... bioRxiv, 2022.06. 02.493408, 2022 | 3 | 2022 |