Tools for kinetic modeling of biochemical networks R Alves, F Antunes, A Salvador Nature biotechnology 24 (6), 667-672, 2006 | 254 | 2006 |
Lipid peroxidation in mitochondrial inner membranes. I. An integrative kinetic model F Antunes, A Salvador, HS Marinho, R Alves, RE Pinto Free Radical Biology and Medicine 21 (7), 917-943, 1996 | 187 | 1996 |
Phenotypes and tolerances in the design space of biochemical systems MA Savageau, PMBM Coelho, RA Fasani, DA Tolla, A Salvador Proceedings of the National Academy of Sciences 106 (16), 6435-6440, 2009 | 104 | 2009 |
Why does SOD overexpression sometimes enhance, sometimes decrease, hydrogen peroxide production? A minimalist explanation R Gardner, A Salvador, P Moradas-Ferreira Free Radical Biology and Medicine 32 (12), 1351-1357, 2002 | 94 | 2002 |
Hydrogen peroxide metabolism and sensing in human erythrocytes: A validated kinetic model and reappraisal of the role of peroxiredoxin II R Benfeitas, G Selvaggio, F Antunes, PMBM Coelho, A Salvador Free Radical Biology and Medicine 74, 35-49, 2014 | 89 | 2014 |
PHGPx and phospholipase A 2/GPx: Comparative importance on the reduction of hydroperoxides in rat liver mitochondria F Antunes, A Salvador, RE Pinto Free Radical Biology and Medicine 19 (5), 669-677, 1995 | 89 | 1995 |
Localized redox relays as a privileged mode of cytoplasmic hydrogen peroxide signaling RDM Travasso, FS dos Aidos, A Bayani, P Abranches, A Salvador Redox biology 12, 233-245, 2017 | 88 | 2017 |
Hydroperoxyl, superoxide and pH gradients in the mitochondrial matrix: a theoretical assessment A Salvador, J Sousa, RE Pinto Free Radical Biology and Medicine 31 (10), 1208-1215, 2001 | 76 | 2001 |
Applied Statistics for Network Biology: Methods in Systems Biology M Dehmer, F Emmert-Streib, A Graber, A Salvador Wiley-VCH, 2011 | 62* | 2011 |
Quantitative evolutionary design of glucose 6-phosphate dehydrogenase expression in human erythrocytes A Salvador, MA Savageau Proceedings of the National Academy of Sciences 100 (24), 14463-14468, 2003 | 58 | 2003 |
Quantifying global tolerance of biochemical systems: design implications for moiety-transfer cycles PMBM Coelho, A Salvador, MA Savageau PLoS computational biology 5 (3), e1000319, 2009 | 42 | 2009 |
Glucose-6-Phosphate dehydrogenase deficiency and neonatal hyperbilirubinemia: Insights on pathophysiology, diagnosis, and gene variants in disease heterogeneity HY Lee, A Ithnin, RZ Azma, A Othman, A Salvador, FC Cheah Frontiers in Pediatrics 10, 875877, 2022 | 39 | 2022 |
Mapping the phenotypic repertoire of the cytoplasmic 2-Cys peroxiredoxin–thioredoxin system. 1. Understanding commonalities and differences among cell types G Selvaggio, PMBM Coelho, A Salvador Redox Biology, 2017 | 33 | 2017 |
In vivo hydrogen peroxide diffusivity in brain tissue supports volume signaling activity A Ledo, E Fernandes, A Salvador, J Laranjinha, RM Barbosa Redox Biology, 102250, 2022 | 32 | 2022 |
Synergism analysis of biochemical systems. I. Conceptual framework A Salvador Mathematical biosciences 163 (2), 105-129, 2000 | 31 | 2000 |
Evolution of enzymes in a series is driven by dissimilar functional demands A Salvador, MA Savageau Proceedings of the National Academy of Sciences 103 (7), 2226-2231, 2006 | 28 | 2006 |
Beyond Overton’s Rule: Quantitative Modeling of Passive Permeation through Tight Cell Monolayers HAL Filipe, A Salvador, JM Silvestre, WLC Vaz, MJ Moreno Molecular pharmaceutics 11 (10), 3696-3706, 2014 | 27 | 2014 |
Relating mutant genotype to phenotype via quantitative behavior of the NADPH redox cycle in human erythrocytes PMBM Coelho, A Salvador, MA Savageau PloS one 5 (9), e13031, 2010 | 26 | 2010 |
Homeostasis of free cholesterol in the blood: a preliminary evaluation and modeling of its passive transport LMBB Estronca, HAL Filipe, A Salvador, MJ Moreno, WLC Vaz Journal of lipid research 55 (6), 1033-1043, 2014 | 23 | 2014 |
Analysis of the Equilibrium Distribution of Ligands in Heterogeneous Media–Approaches and Pitfalls MJJ Moreno, LM Loura, J Martins, A Salvador, A Velazquez-Campoy International Journal of Molecular Sciences 23 (17), 9757, 2022 | 22 | 2022 |