Tau kinetics in neurons and the human central nervous system C Sato, NR Barthélemy, KG Mawuenyega, BW Patterson, BA Gordon, ... Neuron 97 (6), 1284-1298. e7, 2018 | 552 | 2018 |
A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer’s disease NR Barthélemy, Y Li, N Joseph-Mathurin, BA Gordon, J Hassenstab, ... Nature medicine 26 (3), 398-407, 2020 | 451 | 2020 |
Blood plasma phosphorylated-tau isoforms track CNS change in Alzheimer’s disease NR Barthélemy, K Horie, C Sato, RJ Bateman Journal of Experimental Medicine 217 (11), e20200861, 2020 | 329 | 2020 |
Neurofilaments: neurobiological foundations for biomarker applications AR Gafson, NR Barthélemy, P Bomont, RO Carare, HD Durham, JP Julien, ... Brain 143 (7), 1975-1998, 2020 | 204 | 2020 |
Cerebrospinal fluid phospho-tau T217 outperforms T181 as a biomarker for the differential diagnosis of Alzheimer’s disease and PET amyloid-positive patient identification NR Barthélemy, RJ Bateman, C Hirtz, P Marin, F Becher, C Sato, ... Alzheimer's research & therapy 12, 1-11, 2020 | 184 | 2020 |
Head-to-head comparison of 10 plasma phospho-tau assays in prodromal Alzheimer’s disease S Janelidze, D Bali, NJ Ashton, NR Barthélemy, J Vanbrabant, E Stoops, ... Brain 146 (4), 1592-1601, 2023 | 168 | 2023 |
Differential Mass Spectrometry Profiles of Tau Protein in the Cerebrospinal Fluid of Patients with Alzheimer’s Disease, Progressive Supranuclear Palsy, and Dementia with Lewy … NR Barthélemy, A Gabelle, C Hirtz, F Fenaille, N Sergeant, ... Journal of Alzheimer's Disease, 1-11, 2016 | 134 | 2016 |
Tau phosphorylation rates measured by mass spectrometry differ in the intracellular brain versus extracellular cerebrospinal fluid compartments and are differentially affected … NR Barthélemy, N Mallipeddi, P Moiseyev, C Sato, RJ Bateman Frontiers in Aging Neuroscience 11, 121, 2019 | 127 | 2019 |
Tau protein quantification in human cerebrospinal fluid by targeted mass spectrometry at high sequence coverage provides insights into its primary structure heterogeneity NR Barthélemy, F Fenaille, C Hirtz, N Sergeant, S Schraen-Maschke, ... Journal of Proteome Research, 2016 | 115 | 2016 |
CSF tau microtubule binding region identifies tau tangle and clinical stages of Alzheimer’s disease K Horie, NR Barthélemy, C Sato, RJ Bateman Brain 144 (2), 515-527, 2021 | 106 | 2021 |
Soluble TREM2 in CSF and its association with other biomarkers and cognition in autosomal-dominant Alzheimer's disease: a longitudinal observational study E Morenas-Rodríguez, Y Li, B Nuscher, N Franzmeier, C Xiong, ... The Lancet Neurology 21 (4), 329-341, 2022 | 97 | 2022 |
Sleep deprivation affects tau phosphorylation in human cerebrospinal fluid NR Barthélemy, H Liu, W Lu, PT Kotzbauer, RJ Bateman, BP Lucey Annals of neurology 87 (5), 700-709, 2020 | 83 | 2020 |
CSF MTBR-tau243 is a specific biomarker of tau tangle pathology in Alzheimer’s disease K Horie, G Salvadó, NR Barthélemy, S Janelidze, Y Li, Y He, B Saef, ... Nature medicine 29 (8), 1954-1963, 2023 | 56 | 2023 |
SILK studies—capturing the turnover of proteins linked to neurodegenerative diseases RW Paterson, A Gabelle, BP Lucey, NR Barthélemy, CA Leckey, C Hirtz, ... Nature Reviews Neurology 15 (7), 419-427, 2019 | 47 | 2019 |
Antibody-free quantification of seven tau peptides in human CSF using targeted mass spectrometry P Bros, J Vialaret, N Barthélemy, V Delatour, A Gabelle, S Lehmann, ... Frontiers in neuroscience 9, 302, 2015 | 46 | 2015 |
CSF tau microtubule-binding region identifies pathological changes in primary tauopathies K Horie, NR Barthélemy, S Spina, L VandeVrede, Y He, RW Paterson, ... Nature medicine 28 (12), 2547-2554, 2022 | 45 | 2022 |
Quantitative detection of amyloid-β peptides by mass spectrometry: state of the art and clinical applications P Bros, V Delatour, J Vialaret, B Lalere, N Barthelemy, A Gabelle, ... Clinical Chemistry and Laboratory Medicine (CCLM) 53 (10), 1483-1493, 2015 | 45 | 2015 |
Proteomic tools for the investigation of human hair structural proteins and evidence of weakness sites on hair keratin coil segments NR Barthélemy, A Bednarczyk, C Schaeffer-Reiss, D Jullien, ... Analytical biochemistry 421 (1), 43-55, 2012 | 42 | 2012 |
CSF tau phosphorylation occupancies at T217 and T205 represent improved biomarkers of amyloid and tau pathology in Alzheimer’s disease NR Barthélemy, B Saef, Y Li, BA Gordon, Y He, K Horie, E Stomrud, ... Nature Aging 3 (4), 391-401, 2023 | 40 | 2023 |
Regional correlation of biochemical measures of amyloid and tau phosphorylation in the brain K Horie, NR Barthélemy, N Mallipeddi, Y Li, EE Franklin, RJ Perrin, ... Acta Neuropathologica Communications 8, 1-14, 2020 | 39 | 2020 |