| Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8 MR Sprick, E Rieser, H Stahl, A Grosse-Wilde, MA Weigand, H Walczak The EMBO journal 21 (17), 4520-4530, 2002 | 521 | 2002 |
| Stemness of the hybrid epithelial/mesenchymal state in breast cancer and its association with poor survival A Grosse-Wilde, A Fouquier d’Hérouël, E McIntosh, G Ertaylan, A Skupin, ... PloS one 10 (5), e0126522, 2015 | 377 | 2015 |
| Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by … TM Ganten, TL Haas, J Sykora, H Stahl, MR Sprick, SC Fas, A Krueger, ... Cell Death & Differentiation 11 (1), S86-S96, 2004 | 256 | 2004 |
| TRAIL-R deficiency in mice enhances lymph node metastasis without affecting primary tumor development A Grosse-Wilde, O Voloshanenko, SL Bailey, GM Longton, U Schaefer, ... The Journal of clinical investigation 118 (1), 2007 | 214 | 2007 |
| Cancer cell-autonomous TRAIL-R signaling promotes KRAS-driven cancer progression, invasion, and metastasis S von Karstedt, A Conti, M Nobis, A Montinaro, T Hartwig, J Lemke, ... Cancer cell 27 (4), 561-573, 2015 | 199 | 2015 |
| TNF-related apoptosis-inducing ligand mediates tumoricidal activity of human monocytes stimulated by Newcastle disease virus B Washburn, MA Weigand, A Grosse-Wilde, M Janke, H Stahl, E Rieser, ... The Journal of Immunology 170 (4), 1814-1821, 2003 | 154 | 2003 |
| Different mitogen-activated protein kinase signaling pathways cooperate to regulate tumor necrosis factor α gene expression in T lymphocytes A Hoffmeyer, A Grosse-Wilde, E Flory, B Neufeld, M Kunz, UR Rapp, ... Journal of Biological Chemistry 274 (7), 4319-4327, 1999 | 124 | 1999 |
| Pharmacokinetics of intrathecally applied BDNF and effects on spinal motoneurons F Dittrich, G Ochs, A Große-Wilde, U Berweiler, Q Yan, JA Miller, ... Experimental neurology 141 (2), 225-239, 1996 | 108 | 1996 |
| Serine/Threonine kinases 3pK and MAPK-activated protein kinase 2 interact with the basic helix-loop-helix transcription factor E47 and repress its transcriptional activity B Neufeld, A Grosse-Wilde, A Hoffmeyer, BWM Jordan, P Chen, D Dinev, ... Journal of Biological Chemistry 275 (27), 20239-20242, 2000 | 100 | 2000 |
| Transforming growth factor β can mediate apoptosis via the expression of TRAIL in human hepatoma cells K Herzer, TM Ganten, H Schulze‐Bergkamen, A Grosse‐Wilde, ... Hepatology 42 (1), 183-192, 2005 | 43 | 2005 |
| Transforming Growth Factor-β–Mediated Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Expression and Apoptosis in Hepatoma Cells Requires Functional Cooperation between … K Herzer, A Grosse-Wilde, PH Krammer, PR Galle, S Kanzler Molecular Cancer Research 6 (7), 1169-1177, 2008 | 34 | 2008 |
| Metastasis Suppressor Function of Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand-R in Mice: Implications for TRAIL-Based Therapy in Humans? A Grosse-Wilde, CJ Kemp Cancer research 68 (15), 6035-6037, 2008 | 28 | 2008 |
| Loss of inter-cellular cooperation by complete epithelial-mesenchymal transition supports favorable outcomes in basal breast cancer patients A Grosse-Wilde, RE Kuestner, SM Skelton, E MacIntosh, AF d’Hérouël, ... Oncotarget 9 (28), 20018, 2018 | 22 | 2018 |
| 323 Systemic administration of ladiratuzumab vedotin alone or in combination with pembrolizumab results in significant immune activation in the tumor microenvironment in … L Pusztai, H Lu, C Hale, A Grosse-Wilde, J Specht, S Modi, H Han, ... Journal for ImmunoTherapy of Cancer 8 (Suppl 3), 2020 | 3 | 2020 |
| Post-treatment biopsies show evidence of cell cycle arrest and immune cell infiltration into tumors of ladiratuzumab vedotin-treated advanced breast cancer patients J Specht, L Pusztai, A Forero-Torres, M Mita, A Weise, I Krop, ... Annals of Oncology 29, viii92, 2018 | 2 | 2018 |
| Accelerated Publication-Serine/threonine kinases 3pK and MAPK-activated protein kinase 2 interact with the basic helix-loop-helix transcription factor E47 and repress its … B Neufeld, A Grosse-Wilde, A Hoffmeyer, BWM Jordan, P Chen, D Dinev, ... JOURNAL OF BIOLOGICAL CHEMISTRY 275 (27), 20239-20242, 2000 | 2 | 2000 |
| Different MAPK signaling pathways cooperate to regulate TNFα gene expression in T lymphocyte A Hoffmeyer J Biol Chem 274, 4319-4327, 1999 | 2 | 1999 |
| 281 TGF-β is involved in the regulation of apoptosis via trail expression in hepatoma cells K Herzer, A Grosse-Wilde, T Gantrn, H Walczak, PH Krammer Journal of Hepatology, 87, 2004 | 1 | 2004 |
| Abstract LB-045: A tissue-engineered vascularized tumor microenvironment for preclinical testing of anticancer therapeutics H Mann, A Grosse-Wilde Cancer Research 76 (14_Supplement), LB-045-LB-045, 2016 | | 2016 |
| Synergy between epithelial and mesenchymal cells in breast cancer: from mammospheres to predicting patient outcomes A Grosse-Wilde, A d'Herouel, R Kuestner, G Ertaylan, A Skupin, S Huang, ... Cancer Research 74 (19_Supplement), 1918-1918, 2014 | | 2014 |
