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Ning Shen
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Genomic regions flanking E-box binding sites influence DNA binding specificity of bHLH transcription factors through DNA shape
R Gordân, N Shen, I Dror, T Zhou, J Horton, R Rohs, ML Bulyk
Cell reports 3 (4), 1093-1104, 2013
3622013
Aberrant mitochondrial fission in neurons induced by protein kinase Cδ under oxidative stress conditions in vivo
X Qi, MH Disatnik, N Shen, RA Sobel, D Mochly-Rosen
Molecular biology of the cell 22 (2), 256-265, 2011
2952011
Quantitative modeling of transcription factor binding specificities using DNA shape
T Zhou, N Shen, L Yang, N Abe, J Horton, RS Mann, HJ Bussemaker, ...
Proceedings of the National Academy of Sciences 112 (15), 4654-4659, 2015
2582015
Proteome-wide mapping of short-lived proteins in human cells
J Li, Z Cai, LP Vaites, N Shen, DC Mitchell, EL Huttlin, JA Paulo, BL Harry, ...
Molecular cell 81 (22), 4722-4735. e5, 2021
802021
Establishment of expression in the SHORTROOT-SCARECROW transcriptional cascade through opposing activities of both activators and repressors
EE Sparks, C Drapek, A Gaudinier, S Li, M Ansariola, N Shen, ...
Developmental Cell 39 (5), 585-596, 2016
602016
Divergence in DNA specificity among paralogous transcription factors contributes to their differential in vivo binding
N Shen, J Zhao, JL Schipper, Y Zhang, T Bepler, D Leehr, J Bradley, ...
Cell systems 6 (4), 470-483. e8, 2018
512018
p38α regulates expression of DUX4 in a model of facioscapulohumeral muscular dystrophy
LA Rojas, E Valentine, A Accorsi, J Maglio, N Shen, A Robertson, ...
Journal of Pharmacology and Experimental Therapeutics 374 (3), 489-498, 2020
352020
Integration of cancer gene co-expression network and metabolic network to uncover potential cancer drug targets
J Chen, M Ma, N Shen, JJ Xi, W Tian
Journal of proteome research 12 (6), 2354-2364, 2013
272013
Single-cell gene fusion detection by scFusion
Z Jin, W Huang, N Shen, J Li, X Wang, J Dong, PJ Park, R Xi
Nature Communications 13 (1), 1084, 2022
142022
Temporally integrated transcriptome analysis reveals ASFV pathology and host response dynamics
L Lv, T Zhang, H Jia, Y Zhang, A Ahsan, X Zhao, T Chen, Z Shen, N Shen
Frontiers in Immunology 13, 995998, 2022
52022
Low-input lipidomics reveals lipid metabolism remodelling during early mammalian embryo development
L Zhang, J Zhao, SM Lam, L Chen, Y Gao, W Wang, Y Xu, T Tan, H Yu, ...
Nature Cell Biology 26 (2), 278-293, 2024
42024
P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD
AM Cacace, LGAR SOTO, LA Thompson III, OB Wallace, LV Ronco, ...
US Patent 10,537,560, 2020
42020
De novo identification of expressed cancer somatic mutations from single-cell RNA sequencing data
T Zhang, H Jia, T Song, L Lv, DC Gulhan, H Wang, W Guo, R Xi, H Guo, ...
Genome Medicine 15 (1), 115, 2023
32023
P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD
AM Cacace, LGAR SOTO, LA Thompson III, OB Wallace, LV Ronco, ...
US Patent 10,342,786, 2019
32019
MAGPIE: accurate pathogenic prediction for multiple variant types using machine learning approach
Y Liu, T Zhang, N You, S Wu, N Shen
Genome Medicine 16 (1), 3, 2024
22024
Beyond radiologist-level liver lesion detection on multi-phase contrast-enhanced CT images by deep learning
L Wu, H Wang, Y Chen, X Zhang, T Zhang, N Shen, G Tao, Z Sun, Y Ding, ...
Iscience 26 (11), 2023
22023
Use of p38 inhibitors to reduce expression of DUX4
AM Cacace, SLGA Rojas, LA Thompson, OB Wallace, L Ronco, N Shen, ...
22021
Intrinsic specificity differences between transcription factor paralogs partly explain their differential in vivo binding
N Shen, J Zhao, J Schipper, Y Zhang, T Bepler, D Leehr, J Bradley, ...
bioRxiv, 208561, 2017
22017
Mitophagy defect mediates the aging‐associated hallmarks in Hutchinson–Gilford progeria syndrome
Y Sun, L Xu, Y Li, S Jia, G Wang, X Cen, Y Xu, Z Cao, J Wang, N Shen, ...
Aging Cell 23 (6), e14143, 2024
12024
Use of p38 inhibitors to reduce expression of DUX4
AM Cacace, LGAR SOTO, LA Thompson III, OB Wallace, LV Ronco, ...
US Patent 11,479,770, 2022
12022
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