Repurposing doxycycline for synucleinopathies: remodelling of α-synuclein oligomers towards non-toxic parallel beta-sheet structured species F González-Lizárraga, SB Socías, CL Ávila, CM Torres-Bugeau, ... Scientific reports 7 (1), 1-13, 2017 | 122 | 2017 |
Exploiting the therapeutic potential of ready-to-use drugs: Repurposing antibiotics against amyloid aggregation in neurodegenerative diseases SB Socias, F Gonzalez-Lizarraga, CL Avila, C Vera, L Acuña, ... Progress in neurobiology 162, 17-36, 2018 | 44 | 2018 |
Long-term analysis of antibodies elicited by SPUTNIK V: A prospective cohort study in Tucumán, Argentina RE Chahla, RH Tomas-Grau, SI Cazorla, D Ploper, EV Pingitore, ... The Lancet Regional Health–Americas 6, 2022 | 41 | 2022 |
Structural characterization of heparin-induced glyceraldehyde-3-phosphate dehydrogenase protofibrils preventing α-synuclein oligomeric species toxicity CL Avila, CM Torres-Bugeau, LRS Barbosa, EM Sales, MO Ouidja, ... Journal of Biological Chemistry 289 (20), 13838-13850, 2014 | 36 | 2014 |
Characterization of heparin-induced glyceraldehyde-3-phosphate dehydrogenase early amyloid-like oligomers and their implication in α-synuclein aggregation CM Torres-Bugeau, CL Ávila, R Raisman-Vozari, D Papy-Garcia, R Itri, ... Journal of Biological Chemistry 287 (4), 2398-2409, 2012 | 34 | 2012 |
Towards efficient biocatalysts: photo-immobilization of a lipase on novel lysozyme amyloid-like nanofibrils S Chaves, LM Pera, CL Avila, CM Romero, M Baigori, FEM Vieyra, ... RSC advances 6 (11), 8528-8538, 2016 | 27 | 2016 |
Microcin J25 triggers cytochrome c release through irreversible damage of mitochondrial proteins and lipids MV Niklison-Chirou, F Dupuy, LB Pena, SM Gallego, ML Barreiro-Arcos, ... The International Journal of Biochemistry & Cell Biology 42 (2), 273-281, 2010 | 22 | 2010 |
CMT-3 targets different α-synuclein aggregates mitigating their toxic and inflammogenic effects F González-Lizárraga, D Ploper, CL Ávila, SB Socías, ... Scientific reports 10 (1), 20258, 2020 | 17 | 2020 |
Multiscale molecular dynamics of protein aggregation C L Avila, N JD Drechsel, R Alcántara, J Villa-Freixa Current Protein and Peptide Science 12 (3), 221-234, 2011 | 15 | 2011 |
Linear array of conserved sequence motifs to discriminate protein subfamilies: study on pyridine nucleotide-disulfide reductases CL Avila, VA Rapisarda, RN Farías, J De Las Rivas, R Chehín BMC bioinformatics 8, 1-8, 2007 | 14 | 2007 |
Lessons learned from protein aggregation: toward technological and biomedical applications CL Avila, S Chaves, SB Socias, E Vera-Pingitore, F González-Lizárraga, ... Biophysical reviews 9, 501-515, 2017 | 13 | 2017 |
Glyceraldehyde-3-phosphate dehydrogenase tetramer dissociation and amyloid fibril formation induced by negatively charged membranes LM Cortez, CL Ávila, CMT Bugeau, RN Farías, RD Morero, RN Chehín FEBS letters 584 (3), 625-630, 2010 | 12 | 2010 |
Past SARS-CoV-2 infection elicits a strong immune response after a single vaccine dose RE Chahla, R Hernán Tomas-Grau, S Inés Cazorla, D Ploper, ... medRxiv, 2021.03. 14.21253039, 2021 | 11 | 2021 |
How does growth hormone releasing hexapeptide self-assemble in nanotubes? H Santana, CL Avila, I Cabrera, R Páez, V Falcón, A Pessoa, N Ventosa, ... Soft Matter 10 (46), 9260-9269, 2014 | 9 | 2014 |
Role of electrostatics on membrane binding, aggregation and destabilization induced by NAD (P) H dehydrogenases. Implication in membrane fusion CL Avila, BF de Arcuri, F Gonzalez-Nilo, J De Las Rivas, R Chehín, ... Biophysical chemistry 137 (2-3), 126-132, 2008 | 8 | 2008 |
Repurposing doxycycline for synucleinopathies: remodelling of α-synuclein oligomers towards non-toxic parallel beta-sheet structured species. Sci Rep 7: 41755 F González-Lizárraga, SB Socías, CL Ávila, CM Torres-Bugeau, ... | 7 | 2017 |
PAMAM dendrimers of generation 4.5 loaded with curcumin interfere with α-synuclein aggregation DE Igartúa, F González-Lizárraga, CS Martinez, SV Alonso, CL Ávila, ... OpenNano 11, 100140, 2023 | 6 | 2023 |
Elevated Humoral Immune Response to SARS-CoV-2 at High Altitudes Revealed by an Anti-RBD “In-House” ELISA RH Tomas-Grau, D Ploper, CL Ávila, E Vera Pingitore, ... Frontiers in Medicine 8, 720988, 2021 | 6 | 2021 |
Neuroprotective effects of a novel demeclocycline derivative lacking antibiotic activity: From a hit to a promising lead compound R Tomas-Grau, F González-Lizárraga, D Ploper, CL Avila, SB Socías, ... Cells 11 (17), 2759, 2022 | 5 | 2022 |
Prorenins activation by an enzyme from rat plasma (PreR-Co) P Vincent, C Adler, C Avila, C Guardia, E De Vito Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular …, 2002 | 5 | 2002 |