WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy S Qi, Y Zhu, X Liu, P Li, Y Wang, Y Zeng, A Yu, Y Wang, Z Sha, Z Zhong, ... Molecular Cell 82 (10), 1850-1864. e7, 2022 | 61 | 2022 |
Adamts18 deficiency promotes colon carcinogenesis by enhancing β-catenin and p38MAPK/ERK1/2 signaling in the mouse model of AOM/DSS-induced colitis-associated colorectal cancer T Lu, S Dang, R Zhu, Y Wang, Z Nie, T Hong, W Zhang Oncotarget 8 (12), 18979, 2017 | 32 | 2017 |
TERT accelerates BRAF mutant–induced thyroid cancer dedifferentiation and progression by regulating ribosome biogenesis P Yu, N Qu, R Zhu, J Hu, P Han, J Wu, L Tan, H Gan, C He, C Fang, Y Lei, ... Science advances 9 (35), eadg7125, 2023 | 27 | 2023 |
Stabilization of Motin family proteins in NF2-deficient cells prevents full activation of YAP/TAZ and rapid tumorigenesis Y Wang, Y Zhu, Y Gu, M Ma, Y Wang, S Qi, Y Zeng, R Zhu, X Wang, P Yu, ... Cell reports 36 (8), 2021 | 27 | 2021 |
Two Hippo signaling modules orchestrate liver size and tumorigenesis S Qi, Z Zhong, Y Zhu, Y Wang, M Ma, Y Wang, X Liu, R Jin, Z Jiao, R Zhu, ... The EMBO journal 42 (11), e112126, 2023 | 25 | 2023 |
A disintegrin and metalloproteinase with thrombospondin motifs 18 deficiency leads to visceral adiposity and associated metabolic syndrome in mice R Zhu, M Cheng, T Lu, N Yang, S Ye, YH Pan, T Hong, S Dang, W Zhang The American journal of pathology 188 (2), 461-473, 2018 | 25 | 2018 |
ADAMTS18 deficiency affects neuronal morphogenesis and reduces the levels of depression-like behaviors in mice R Zhu, YH Pan, L Sun, T Zhang, C Wang, S Ye, N Yang, T Lu, ... Neuroscience 399, 53-64, 2019 | 22 | 2019 |
ADAMTS18 deficiency leads to pulmonary hypoplasia and bronchial microfibril accumulation T Lu, X Lin, YH Pan, N Yang, S Ye, Q Zhang, C Wang, R Zhu, T Zhang, ... Iscience 23 (9), 2020 | 16 | 2020 |
WWC1/2 regulate spinogenesis and cognition in mice by stabilizing AMOT R Cao, R Zhu, Z Sha, S Qi, Z Zhong, F Zheng, Y Lei, Y Tan, Y Zhu, ... Cell Death & Disease 14 (8), 491, 2023 | 9 | 2023 |
Glucose-induced and ChREBP: MLX-mediated lipogenic program promotes hepatocellular carcinoma development A Yu, P Yu, Y Zhu, R Zhu, R Sun, D Ye, FX Yu Oncogene 42 (43), 3182-3193, 2023 | 7 | 2023 |
Proteolytic activation of angiomotin by DDI2 promotes angiogenesis Y Wang, Y Zhu, Y Wang, Y Chang, F Geng, M Ma, Y Gu, A Yu, R Zhu, ... The EMBO Journal 42 (15), e112900, 2023 | 6 | 2023 |
Gene therapy for diffuse pleural mesotheliomas in preclinical models by concurrent expression of NF2 and SuperHippo R Zhu, X Liu, X Zhang, Z Zhong, S Qi, R Jin, Y Gu, Y Wang, C Ling, ... Cell Reports Medicine 5 (10), 2024 | 2 | 2024 |
ADAMTS18 deficiency associates extracellular matrix dysfunction with a higher risk of HER2-positive mammary tumorigenesis and metastasis J Nie, S Dang, R Zhu, T Lu, W Zhang Breast Cancer Research 26 (1), 19, 2024 | 2 | 2024 |
The development of monoclonal anti-ADAMTS18 antibodies with precise validation of ADAMTS18 post-translational modification status in living organisms R Zhu, M Cheng, S Ye, M Liu, L Sun, T Lu, N Yang, T Hong, S Dang, ... Biochemical and biophysical research communications 492 (3), 404-411, 2017 | 2 | 2017 |
Advances towards potential cancer therapeutics targeting Hippo signaling R Zhu, Z Jiao, FX Yu Biochemical Society Transactions 52 (6), 2399-2413, 2024 | | 2024 |
Vascular Proteomics Reveals Critical Roles of ADAMTS18 in Stroke Associated with Imbalanced Level of Von Willebrand Factor Versus ADAMTS13 R Zhu, YH Pan, T Lu, S Dang, CC Liao, W Zhang Blood 132, 3731, 2018 | | 2018 |