Mitochondria in acute myocardial infarction and cardioprotection CJA Ramachandra, S Hernandez-Resendiz, GE Crespo-Avilan, YH Lin, ... EBioMedicine 57, 2020 | 199 | 2020 |
Re-trafficking of hERG reverses long QT syndrome 2 phenotype in human iPS-derived cardiomyocytes A Mehta, GL Sequiera, CJA Ramachandra, Y Sudibyo, Y Chung, J Sheng, ... Cardiovascular research 102 (3), 497-506, 2014 | 130 | 2014 |
Identification of a targeted and testable antiarrhythmic therapy for long-QT syndrome type 2 using a patient-specific cellular model A Mehta, CJA Ramachandra, P Singh, A Chitre, CH Lua, M Mura, L Crotti, ... European heart journal 39 (16), 1446-1455, 2018 | 117 | 2018 |
Manipulating energy migration within single lanthanide activator for switchable upconversion emissions towards bidirectional photoactivation Q Mei, A Bansal, MKG Jayakumar, Z Zhang, J Zhang, H Huang, D Yu, ... Nature Communications 10 (1), 4416, 2019 | 89 | 2019 |
Molecular pathogenesis of Marfan syndrome CJA Ramachandra, A Mehta, KWQ Guo, P Wong, J Le Tan, W Shim International journal of cardiology 187, 585-591, 2015 | 86 | 2015 |
Oxidative stress in cardiac hypertrophy: From molecular mechanisms to novel therapeutic targets CJA Ramachandra, S Cong, X Chan, EP Yap, F Yu, DJ Hausenloy Free Radical Biology and Medicine 166, 297-312, 2021 | 81 | 2021 |
Efficient recombinase-mediated cassette exchange at the AAVS1 locus in human embryonic stem cells using baculoviral vectors CJA Ramachandra, M Shahbazi, TWX Kwang, Y Choudhury, XY Bak, ... Nucleic acids research 39 (16), e107-e107, 2011 | 59 | 2011 |
Targeting mitochondrial fission using Mdivi-1 in a clinically relevant large animal model of acute myocardial infarction: a pilot study SB Ong, XY Kwek, K Katwadi, S Hernandez-Resendiz, GE Crespo-Avilan, ... International journal of molecular sciences 20 (16), 3972, 2019 | 57 | 2019 |
Myeloperoxidase as a multifaceted target for cardiovascular protection CJA Ramachandra, KPMM Ja, J Chua, S Cong, W Shim, DJ Hausenloy Antioxidants & redox signaling 32 (15), 1135-1149, 2020 | 56 | 2020 |
Fatty acid metabolism driven mitochondrial bioenergetics promotes advanced developmental phenotypes in human induced pluripotent stem cell derived cardiomyocytes CJA Ramachandra, A Mehta, P Wong, KPMM Ja, R Fritsche-Danielson, ... International journal of cardiology 272, 288-297, 2018 | 45 | 2018 |
iPSC‐derived human cardiac progenitor cells improve ventricular remodelling via angiogenesis and interstitial networking of infarcted myocardium KPMM Ja, Q Miao, NGZ Tee, SY Lim, M Nandihalli, CJA Ramachandra, ... Journal of cellular and molecular medicine 20 (2), 323-332, 2016 | 44 | 2016 |
Sheathless acoustic fluorescence activated cell sorting (aFACS) with high cell viability P Li, M Liang, X Lu, JJM Chow, CJA Ramachandra, Y Ai Analytical chemistry 91 (24), 15425-15435, 2019 | 41 | 2019 |
Association of cardiomyopathy with MYBPC3 D389V and MYBPC3Δ25bpIntronic deletion in South Asian descendants SK Viswanathan, MJ Puckelwartz, A Mehta, CJA Ramachandra, ... JAMA cardiology 3 (6), 481-488, 2018 | 40 | 2018 |
Functional odontoblastic-like cells derived from human iPSCs H Xie, N Dubey, W Shim, CJA Ramachandra, KS Min, T Cao, V Rosa Journal of Dental Research 97 (1), 77-83, 2018 | 40 | 2018 |
Phasic modulation of Wnt signaling enhances cardiac differentiation in human pluripotent stem cells by recapitulating developmental ontogeny A Mehta, CJA Ramachandra, GL Sequiera, Y Sudibyo, M Nandihalli, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1843 (11), 2394-2402, 2014 | 38 | 2014 |
Inhibiting cardiac myeloperoxidase alleviates the relaxation defect in hypertrophic cardiomyocytes CJA Ramachandra, MMJ Kp, J Chua, S Hernandez-Resendiz, EA Liehn, ... Cardiovascular research 118 (2), 517-530, 2022 | 36 | 2022 |
Amorphous SiO2 nanoparticles promote cardiac dysfunction via the opening of the mitochondrial permeability transition pore in rat heart and human cardiomyocytes O Lozano, C Silva-Platas, H Chapoy-Villanueva, BE Pérez, JG Lees, ... Particle and Fibre Toxicology 17, 1-16, 2020 | 36 | 2020 |
A systemic evaluation of cardiac differentiation from mRNA reprogrammed human induced pluripotent stem cells A Mehta, V Verma, M Nandihalli, CJA Ramachandra, GL Sequiera, ... PloS one 9 (7), e103485, 2014 | 36 | 2014 |
Targeted transgene insertion into the AAVS1 locus driven by baculoviral vector‐mediated zinc finger nuclease expression in human‐induced pluripotent stem cells FC Tay, WK Tan, SL Goh, CJA Ramachandra, CH Lau, H Zhu, C Chen, ... The journal of gene medicine 15 (10), 384-395, 2013 | 33 | 2013 |
The KCNH2-IVS9-28A/G mutation causes aberrant isoform expression and hERG trafficking defect in cardiomyocytes derived from patients affected by Long QT Syndrome type 2 M Mura, A Mehta, CJ Ramachandra, R Zappatore, F Pisano, MC Ciuffreda, ... International Journal of Cardiology 240, 367-371, 2017 | 29 | 2017 |