Novel adenovirus-based vaccines induce broad and sustained T cell responses to HCV in man E Barnes, A Folgori, S Capone, L Swadling, S Aston, A Kurioka, J Meyer, ... Science translational medicine 4 (115), 115ra1-115ra1, 2012 | 501 | 2012 |
A human vaccine strategy based on chimpanzee adenoviral and MVA vectors that primes, boosts, and sustains functional HCV-specific T cell memory L Swadling, S Capone, RD Antrobus, A Brown, R Richardson, EW Newell, ... Science translational medicine 6 (261), 261ra153-261ra153, 2014 | 388 | 2014 |
Pre-existing polymerase-specific T cells expand in abortive seronegative SARS-CoV-2 L Swadling, MO Diniz, NM Schmidt, OE Amin, A Chandran, E Shaw, ... Nature 601 (7891), 110-117, 2022 | 338 | 2022 |
IL-2high tissue-resident T cells in the human liver: Sentinels for hepatotropic infection LJ Pallett, J Davies, EJ Colbeck, F Robertson, N Hansi, NJW Easom, ... Journal of Experimental Medicine 214 (6), 1567-1580, 2017 | 327 | 2017 |
CD161 defines a transcriptional and functional phenotype across distinct human T cell lineages JR Fergusson, KE Smith, VM Fleming, N Rajoriya, EW Newell, ... Cell reports 9 (3), 1075-1088, 2014 | 304 | 2014 |
Immune boosting by B.1.1.529 (Omicron) depends on previous SARS-CoV-2 exposure CJ Reynolds, C Pade, JM Gibbons, AD Otter, KM Lin, D Muñoz Sandoval, ... Science 377 (6603), eabq1841, 2022 | 297 | 2022 |
Circulating and intrahepatic antiviral B cells are defective in hepatitis B AR Burton, LJ Pallett, LE McCoy, K Suveizdyte, OE Amin, L Swadling, ... The Journal of clinical investigation 128 (10), 4588-4603, 2018 | 257 | 2018 |
Discordant neutralizing antibody and T cell responses in asymptomatic and mild SARS-CoV-2 infection CJ Reynolds, L Swadling, JM Gibbons, C Pade, MP Jensen, MO Diniz, ... Science immunology 5 (54), eabf3698, 2020 | 198 | 2020 |
CD161intCD8+ T cells: a novel population of highly functional, memory CD8+ T cells enriched within the gut JR Fergusson, MH Hühn, L Swadling, LJ Walker, A Kurioka, A Llibre, ... Mucosal immunology 9 (2), 401-413, 2016 | 131 | 2016 |
Longevity and replenishment of human liver-resident memory T cells and mononuclear phagocytes LJ Pallett, AR Burton, OE Amin, S Rodriguez-Tajes, AA Patel, N Zakeri, ... Journal of Experimental Medicine 217 (9), 2020 | 92 | 2020 |
IL-15 overcomes hepatocellular carcinoma-induced NK cell dysfunction NJW Easom, KA Stegmann, L Swadling, LJ Pallett, AR Burton, D Odera, ... Frontiers in immunology 9, 1009, 2018 | 89 | 2018 |
Ever closer to a prophylactic vaccine for HCV L Swadling, P Klenerman, E Barnes Expert opinion on biological therapy 13 (8), 1109-1124, 2013 | 87 | 2013 |
Targeted reconstruction of T cell receptor sequence from single cell RNA-seq links CDR3 length to T cell differentiation state S Afik, KB Yates, K Bi, S Darko, J Godec, U Gerdemann, L Swadling, ... Nucleic acids research 45 (16), e148-e148, 2017 | 79 | 2017 |
T cells in COVID-19—united in diversity L Swadling, MK Maini Nature immunology 21 (11), 1307-1308, 2020 | 78 | 2020 |
Autophagy in T cells from aged donors is maintained by spermidine and correlates with function and vaccine responses G Alsaleh, I Panse, L Swadling, H Zhang, FC Richter, A Meyer, J Lord, ... Elife 9, e57950, 2020 | 71 | 2020 |
Human liver memory CD8+ T cells use autophagy for tissue residence L Swadling, LJ Pallett, MO Diniz, JM Baker, OE Amin, KA Stegmann, ... Cell reports 30 (3), 687-698. e6, 2020 | 67 | 2020 |
Chronic hepatitis C viral infection subverts vaccine‐induced T‐cell immunity in humans C Kelly, L Swadling, S Capone, A Brown, R Richardson, J Halliday, ... Hepatology 63 (5), 1455-1470, 2016 | 63 | 2016 |
Targeting human Acyl-CoA: cholesterol acyltransferase as a dual viral and T cell metabolic checkpoint NM Schmidt, PAC Wing, MO Diniz, LJ Pallett, L Swadling, JM Harris, ... Nature Communications 12 (1), 2814, 2021 | 59 | 2021 |
Blood transcriptional biomarkers of acute viral infection for detection of pre-symptomatic SARS-CoV-2 infection: a nested, case-control diagnostic accuracy study RK Gupta, J Rosenheim, LC Bell, A Chandran, JA Guerra-Assuncao, ... The Lancet Microbe 2 (10), e508-e517, 2021 | 58 | 2021 |
Characterisation and induction of tissue-resident gamma delta T-cells to target hepatocellular carcinoma N Zakeri, A Hall, L Swadling, LJ Pallett, NM Schmidt, MO Diniz, ... Nature Communications 13 (1), 1372, 2022 | 57 | 2022 |